Are Your Symptoms Caused By Coronary Artery Disease?

2018-04-09T08:01:00

(BPT) – A Simple Blood Test Can Help Doctors Determine Your Current Likelihood of Having a Blockage in Your Heart Arteries

Obstructive coronary artery disease (CAD), also known as a blockage in the heart arteries, has many telltale signs. Chest discomfort. Heartburn. Tightness or pressure in the throat, jaw, shoulder, abdomen, back or arm. Yet all these signs can signal other issues going on inside the patient. Too much spicy food, stress, a pulled muscle. The list can grow rather long. Determining the cause of these symptoms can be tricky business. So how do you and your doctor correctly identify the cause of your specific symptoms? It can be as easy as a simple blood test.

Understanding the results of the blood test is just as easy as getting the blood test done. This simple blood test is scored on a scale of 1-40. Those with low scores, defined as ≤ 15, can be safely assessed as having symptoms unlikely to be caused by CAD, whereas patients with higher scores have a higher likelihood of CAD. Patients with low scores can be spared invasive and potentially risky cardiac tests and procedures, while those with higher scores can receive additional testing necessary to achieve their proper diagnosis and treatment.

Recently, the results of the registry study, called PRESET,1 looked at how effective the test does what it was designed to do. This simple blood test minimized unnecessary cardiology referrals and additional cardiac testing for low-risk patients. This means reducing patient exposure to radiation from a nuclear stress test or coronary CT scan, decreased likelihood of skin rashes where electrodes are placed for echocardiograms, electrocardiograms, exercise stress tests and more, reduced risk of dye reactions or risk associated with surgical heart procedures such as possible injury to the artery, kidney damage, bleeding complications, and more. These patients can get reliable information without the risks of the traditional tests.

The test (known as the Corus® CAD blood test) incorporates age, sex and gene expression measurements into a single score that indicates a person’s current likelihood of obstructive CAD. Unlike a genetic test, which provides information about a patient’s future risk of disease, this test provides the current likelihood of blockage in his or her heart artery. It’s much safer for the patient and has the benefit of saving the healthcare system money by reducing unnecessary tests and procedures.

Recently, the American Heart Association highlighted the Corus CAD test in a new 2017 Scientific Statement2 about how precision medicine can be used to diagnose and predict cardiovascular disorders. The AHA’s statement confirms that this simple blood test has been proven valid and useful in clinical studies. If you are concerned about the symptoms of obstructive CAD, talk with your doctor.

For more information about the Corus CAD blood test, visit www.corusCAD.com.

Fast Facts

  • One in seven deaths among Americans is caused by CAD3
  • Traditional tests carry various risks
  • A simple blood test called Corus CAD helps doctors identify patients who are at low risk so that unnecessary and potentially harmful cardiac tests can be avoided, as well as those at high risk so appropriate next steps can be taken

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1 Ladapo JA, Budoff M, Sharp D, et al. Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease. Am J Med. 2017;130(4):482.e11-482.e17.

2 Musunuru K, Ingelsson E, Fornage M, et al. The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association. Circ Cardiovasc Genet. 2017;10(4):e1-e25.

3 Benjamin EJ, Blaha MJ, Chiuve SE, et al. On Behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics – 2017 Update: A Report from the American Heart Association. Circulation. 2017;135(10):e146-e603.


Don’t suffer in silence if you have these symptoms

2018-04-09T12:01:00

(BPT) – “As a doctor, I want patients to have open conversations with me about any symptoms they may experience without feeling uncomfortable,” said Dr. Howard Franklin, MBA, vice president of medical affairs and strategy at Salix Pharmaceuticals. “But, I understand that patients may sometimes choose not to talk about symptoms they find embarrassing.”

Such is the case when it comes to discussing bowel movements. For people who experience abdominal pain and diarrhea, it is important to discuss these symptoms with your doctor as they may be signs of irritable bowel syndrome with diarrhea (IBS-D).

A report published by the American Journal of Gastroenterology found that up to 75 percent of individuals living with irritable bowel syndrome may be undiagnosed. You are not alone.

For the up to 16 million Americans living with IBS-D, it is often an uncomfortable disorder that can reduce a patient’s quality of life. IBS-D affects twice as many women as men and often occurs in people younger than 45. It can cause interference with daily activities and avoidance of certain foods.

If you’ve experienced these symptoms, Franklin offers two important steps you can take.

Understand the disorder

IBS-D is a disorder of the large intestine and though the precise cause is unknown, it is believed that there are various factors that can play a role in creating symptoms. Stronger, longer muscle contractions in the intestines and poorly coordinated signals between the brain and the intestines are all possible causes for IBS-D. Often, IBS-D is triggered by food, caffeine, stress, carbonated drinks, artificial sugars or infectious diarrhea.

Changes in bacteria in the gut have also been linked to symptoms of IBS-D. In a healthy state, the microbiome and the human host have a mutually beneficial relationship as the host intestine provides the bacteria with an environment to flourish and the bacteria provides physiological stability. A change in the number of bacteria and in their type can disrupt this relationship.

Talk to your doctor

Don’t hesitate to initiate the conversation with your doctor if you experience symptoms of IBS-D.

It’s time to talk to your doctor if:

* Your abdominal pain keeps coming back at least one day per week in the last three months

* The frequency of your bowel movements, and/or the way your stool looks has changed

Here are a few ways you can prepare for a conversation with your doctor:

1. Write down your symptoms and triggers.

2. Make a list of all your medications.

3. Plan questions in advance, such as: What are the likely causes of my symptoms? Should I make any changes to my diet or lifestyle? What treatment options do you recommend for me?

There is no need to suffer with IBS-D in silence. Speak up to your doctor and, together, find ways to manage the disorder. For more information about IBS-D, visit www.LetsTalk-2.com.


10 things you don’t know about meningitis

2018-04-10T07:01:00

(BPT) – By Jamie Schanbaum, GSK spokesperson, U.S. Para-athlete and meningitis survivor

Before I contracted bacterial meningitis in 2008, I had never heard of it. I didn’t know how it was transmitted, what the symptoms were or how to help prevent it. After spending seven months in the hospital and losing all my fingers and both legs below the knee, I learned as much as I could about meningococcal disease. Now I want others to know what I didn’t.

  1. Meningococcal meningitis, often referred to as meningitis, is an inflammation of the protective membranes, or meninges, covering the brain and spinal cord.[1]
  2. About one in 10 people carry the bacteria, Neisseria meningitidis, that can cause meningitis. These bacteria live in the back of the nose and throat. People who have the bacteria without any signs or symptoms of the disease are called “carriers.”[2]
  3. Meningitis is uncommon but can be fatal. About one in 10 people infected with meningococcal disease will die.[3]
  4. About one in five meningitis survivors will suffer long-term disability, such as loss of limbs (like me), brain damage, deafness and nervous system problems.[4]
  5. Young adults, including college students and those living in close quarters, are at increased risk for meningitis due to close contact with each other, sharing drinks or eating utensils, kissing or even just coughing.[5],[6] I was 20 years old and in my first semester at the University of Texas when I contracted meningitis. I didn’t know about this increased risk.
  6. Early symptoms may be similar to those of a cold or the flu, but can progress quickly and can be fatal, or cause disability within 24 hours.[7],[8] Symptoms can include fever, headache and stiff neck as well as nausea, vomiting, sensitivity to light and confusion.[9] Everyone’s symptoms can be slightly different, however. For example, I had nausea and vomiting, but also felt exhausted. My hands and feet were extremely sensitive to touching cold objects, like the sink faucet and tile floors. In just 14 hours, I went from thinking I had the flu to being admitted to the hospital. My experience may not be the same as others, so it’s important to know all the possible signs and symptoms and to seek medical help quickly.
  7. There are five different vaccine-preventable serogroups of meningitis – A, B, C, W and Y. Groups B, C and Y are the most common groups of meningitis in the U.S.[10]
  8. There are two different types of vaccines needed to help protect against the five vaccine-preventable serogroups of meningitis.[11] It’s important to know that even if you’ve had a vaccine for serogroups A, C, W and Y, you need a different vaccine to help protect against serogroup B.[12]
  9. Despite the availability of serogroup B meningococcal vaccination since 2014, less than 10 percent of teens and young adults have been vaccinated, even though serogroup B accounts for 30 percent of all meningitis cases in the U.S.[13],[14]
  10. The CDC says all 11- to 12-year-olds should be vaccinated against meningitis A, C, W and Y and recommends a booster at age 16. Additionally, the CDC says teens and young adults (ages 16 through 23) also may be vaccinated against meningitis B, preferably at 16 through 18 years of age. Though vaccination may not protect all recipients, it’s the best way to help prevent the disease.[15],[16]

I consider myself to be very fortunate not only because I survived, but also because now I have an opportunity to educate others. I encourage parents of teens and young adults to talk to their child’s healthcare provider about meningitis and the two different types of vaccines needed to help protect against the disease.


[1] Centers for Disease Control and Prevention. Meningitis. March 28, 2018. Available at: https://www.cdc.gov/meningitis/index.html. Page 1, Paragraph 1.

[2] Centers for Disease Control and Prevention. Meningococcal Disease. Causes and Spread to Others. March 28, 2018. Available at: https://www.cdc.gov/meningococcal/about/causes-transmission.html/, Page 1, Paragraph 1.

[3] Centers for Disease Control and Prevention. Meningococcal Disease: Technical and Clinical Information. June 2016. Available at: http://www.cdc.gov/meningococcal/clinical-info.html. Page 1, Paragraph 4, Lines 1-3.

[4] Centers for Disease Control and Prevention. Meningococcal Disease: Technical and Clinical Information. June 2016. Available at: http://www.cdc.gov/meningococcal/clinical-info.html. Page 1, Paragraph 4, Lines 1-3.

[5] Centers for Disease Control and Prevention. Meningococcal Disease. March 28, 2017. Available at: https://www.cdc.gov/meningococcal/about/causes-transmission.html. Page 1, Paragraph 3.

[6] Centers for Disease Control and Prevention. Manual for the Surveillance of Vaccine-Preventable Diseases: Chapter 8: Meningococcal Disease. April 2014. Available at: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt08-mening.html. Page 1, Paragraphs 10-12.

[7] Centers for Disease Control and Prevention. Manual for the Surveillance of Vaccine-Preventable Diseases: Chapter 8: Meningococcal Disease. April 2014. Available at: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt08-mening.html. Page 1, Paragraphs 10-12.

[8] Centers for Disease Control and Prevention. Meningococcal Disease: Signs & Symptoms. July 2016. Available at: https://www.cdc.gov/meningococcal/about/symptoms.html. Page 1, Paragraphs 1- 2.

[9] Centers for Disease Control and Prevention. Meningococcal Disease: Signs & Symptoms. July 2016. Available at: https://www.cdc.gov/meningococcal/about/symptoms.html. Page 1, Paragraphs 1- 2.

[10] Centers for Disease Control and Prevention. Meningococcal Disease. Causes and Spread to Others. March 28, 2018. Available at https://www.cdc.gov/meningococcal/about/causes-transmission.html/, Page 1, Paragraph 1

[11] Centers for Disease Control and Prevention. Vaccine Information Statements (VISs): Meningococcal ACWY Vaccines (MenACWY and MPSV4) VIS. March 2016. Available at: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/mening.html. Page 1, Paragraph 6.

[12] Centers for Disease Control and Prevention. Vaccine Information Statements (VISs): Meningococcal ACWY Vaccines (MenACWY and MPSV4) VIS. March 2016. Available at: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/mening.html. Page 1, Paragraph 6.

[13] GSK, data on file.

[14] Centers for Disease Control and Prevention. Manual for the Surveillance of Vaccine-Preventable Diseases: Chapter 8: Meningococcal Disease. April 2014. Available at: http://www.cdc.gov/vaccines/pubs/surv-manual/chpt08-mening.html. Page 1, Paragraph 3, Line 2.

[15] Centers for Disease Control and Prevention. Meningococcal Vaccination. March 2018. Available at: https://www.cdc.gov/vaccines/vpd/mening/index.html. Page 1, Paragraph 2.

[16] Centers for Disease Control and Prevention. Meningococcal Vaccination: What Everyone Should Know. March 2018. Available at: https://www.cdc.gov/vaccines/vpd/mening/public/index.html. Page 1, Paragraph 4.


Problem Gambling: Know When to Stop Before You Start

2018-04-10T15:09:00

(BPT) – The bright lights. The energy and laughter that fills the room. Casinos are fun and exciting to the vast majority of people but for some, they can be problematic.

Casinos are a form of entertainment, so how do you ensure what’s meant to be a fun and leisurely activity continues to be a positive experience? Time spent at a casino should be a planned and budgeted entertainment option — like you would approach an evening out for dinner or a sporting event. There are preventative measures that can be taken to help ensure that an experience at a casino remains a fun one.

Leading experts in the field of gambling research maintain that it starts with being an informed consumer who understands the realities of gaming. “Being informed means understanding your thoughts about the next big win, beating the odds, and finding the hot machine or deck of cards,” said Dr. James Whelan of the University of Memphis. “Misunderstanding these thoughts about chance can lead to harmful mistakes and excessive losses of money. Informed consumers know that setting limits on how much you spend and how long you play is the best way to not let these thoughts result in you losing more than you can afford.”

Here’s what everyone should keep in mind before their next casino visit.

Betting on a winning streak

It’s always exciting to hit a jackpot, but winning streaks are highly uncommon and beyond anyone’s control. Each spin of the wheel or roll of the dice is an independent event, which means that the chances of a specific outcome aren’t influenced by previous outcomes. So rolling snake eyes once makes you no more (or less) likely to roll snake eyes again.

The chances of beating the odds

Casino games are designed with a house advantage. Mathematically, the house advantage is a measure of how much the house expects to win, expressed as a percentage of the player’s wager. For example, in a wager with a house advantage of 5 percent, the player will lose, on average over time, $5 for every $100 wagered. Because the odds always favor the house, the longer or faster a person plays a casino game, the more the person should expect to lose even in skill­-based or hybrid games. In the same way, the more a person wagers, the more the person should expect to lose.

Believing in superstitions

It might be fun to imagine that rubbing a rabbit’s foot improves a player’s chances of hitting a jackpot, but the reality is that this “magical thinking” has no impact whatsoever. Cheating aside, there’s nothing a player can do — no ritual or lucky charm — to influence the outcome of any casino game. Superstitions can’t determine whether a player wins or loses because every casino game — whether it’s blackjack, craps or a slot machine — is based on randomness, or on chance.

Lisa Arroyo has worked at Harrah’s Joliet Casino in Illinois for the past 25 years. Like everyone who works at a Caesars Entertainment property, Arroyo thinks about gambling as a fun activity you pay for, like going to the movies or to a theater performance.

Arroyo has heard customers laughing and having fun playing blackjack — and she has also heard customers make troubling statements that have caused her concern. “We definitely don’t want people to come in and spend more than what they have budgeted. We want our guests to simply have fun and gamble responsibly. If someone makes a statement or series of statements that concern us, we will have a discussion with the patron and inform them of responsible gaming options and alternatives if needed.”

Gambling responsibly?

Is responsible gaming an oxymoron? Not at all. Arroyo wants gambling to be a choice made for the right reasons. She is one of the advocates of Caesars Entertainment’s Responsible Gaming program, the first hospitality gambling program of its kind to formally train employees on the importance of Responsible Gaming.

The premise of the program involves Arroyo and her colleagues across Caesars’ global network of properties, called Responsible Gaming (RG) Ambassadors, who are celebrating their 15th year of assisting casino guests who may not be gambling responsibly. If comments or statements are made that are concerning to any employee, that concern is brought to the attention of the RG Ambassador who will sit down with the guest to address the reported concern, offer problem gambling program assistance and help resources, and answer questions. “We just let them know that if they feel like they might have a problem, we’re here to answer questions and help,” said Arroyo.

She informs people who express they might have a gambling problem to ask themselves some of the following questions.

* Do I lose time from work due to gambling?

* Is gambling making my home life unhappy?

* Have I ever felt remorse after gambling?

* Do I ever gamble to get money to help pay debts or to otherwise solve financial difficulties?

* Does gambling cause a decrease in my ambition or efficiency?

* Do I ever gamble longer than I had planned?

Caesars Entertainment wants everyone who plays at its casinos to be there for the right reason — to simply have fun. For the past 25 years, Caesars has been committed to promoting responsible gaming and has provided assistance to guests who may not be gambling responsibly. This year, Caesars’ Responsible Gaming Ambassador Program is celebrating its 15th anniversary with 815 Responsible Gaming Ambassadors that may assist guests with problem gambling help resources.


Hard water proves hard on your wallet

2018-04-11T07:01:01

(BPT) – Hard water, which contains high levels of calcium and magnesium, can be found in nearly 90 percent of American homes. These minerals cause scaling, a buildup that clogs waterlines and plumbing forcing appliances to work harder and operate less efficiently. The scale may also harbor bacteria. The only way to truly remove the hard and soft scale from household water systems is with salt-based water softeners.

The environmental and cost benefits of salt-based water softening are significant. Hard water scaling can cause your showerhead to lose up to 75 percent of its flow rate in just 18 months. Hard water also interacts negatively with soap, reducing its cleaning power. Soft water is up to 12 times more effective at cleaning dishes than increasing the amount of detergent used.

According to the Water Quality Research Foundation for washing machines, the most important factor in removing stains from clothing was water softness. Reduction of water hardness was up to 100 times more effective at stain removal than increasing the detergent dose or washing with hotter water. In fact, soft water can reduce soap use by as much as half. Hard water can also reduce the efficiency of water heaters and increase electricity costs by as much as 48 percent, according to the Battelle Memorial Institute.

Hard water scaling doesn’t just harm your appliances and wallet, it can harm your health as well. The piping used in home plumbing, whether it is copper or PVC, has very smooth interior surfaces that don’t permit bacteria to settle and grow. However, hard water results in scale formation on the interior surfaces of those pipes and that provides a perfect home for bacteria.

Researchers at the School of Sustainable Engineering at Arizona State University found bacteria may grow in pipes filled with both hard scale and soft scale at the same rate. This is important new information because some forms of water conditioning produce this soft scale. The only solution is to remove both hard and soft scale in the pipes with a salt-based water softener.

Hard water you use to wash your fresh fruits and vegetables may actually contain more bacteria, and the problem isn’t only in the kitchen. When you take a hot shower the steam you are inhaling can also contain the same microbial contamination that is in the rest of your plumbing, exposing you to bacteria such as Legionella, which can cause Legionnaire’s disease.

A salt-based water softener is the most functional and cost-effective means of removing hardness minerals. It is a time-tested, highly reliable tool to improve health and to lower maintenance costs for home appliances like dishwashers and washing machine. It also reduces the need for detergents and high-water temperatures, leading to a smaller household carbon footprint.