Category: Brandpoint Health

2018-08-30T14:01:00

(BPT) – Jeanie Stich and her husband Elfie have constantly been on the move throughout their 32 years of marriage. In 1999, after 20 plus years of working together at a major aircraft company, the two retired, put their home in Washington state up for sale and set off to explore the country in their new RV. Thirteen adventure-filled years on the road later, the couple settled at a retirement resort in Arizona and filled their days socializing with friends and playing cards. Jeanie even picked up the sport of pickleball.

All was just as the couple had planned and imagined, until – toward the end of 2015 – Jeanie developed a dry cough that she couldn’t shake and began becoming noticeably more tired from typical activity than usual. Jeanie and Elfie feared something was very wrong and, unfortunately, their instincts were correct.

Jeanie’s symptoms persisted for about a month, at which point she went to see her doctor. She was diagnosed with bronchitis and prescribed antibiotics, but the medication didn’t help. By February, walking even small distances was too much, and Jeanie was spending her days in bed or a chair. She went back to the doctor and, this time, was diagnosed with pneumonia. Her doctor prescribed another course of antibiotics, and again the medication didn’t help.

Finally, Jeanie was referred to a lung specialist, or pulmonologist. After a handful of tests, Jeanie and Elfie finally learned what was really wrong – Jeanie had idiopathic pulmonary fibrosis, or IPF, a rare lung disease that causes permanent scarring of the lungs. As the pulmonologist explained, IPF affects up to 132,000 Americans and a proper diagnosis can take years, as the symptoms of IPF, including breathlessness and a dry persistent cough, are similar to other more common and recognizable lung diseases like COPD and asthma.

Jeanie was distraught – particularly since the doctor informed her that the disease had progressed too far for treatment and that she should get her affairs in order. “Elfie and I spent that weekend praying, crying and trying to figure out what had just happened to our perfect life,” remembers Jeanie. “I was devastated by the thought of no longer sharing a life with my husband, my kids, and my seven grandkids. But I looked at Elfie and said ‘these are the cards we’ve been dealt, we’re going to play ‘em. We’re going to get through this.’”

Elfie was also overwhelmed and, understandably, frightened that he might lose his best friend and love of his life. Still, he was determined to stay strong and help Jeanie battle this bleak prognosis. As a first step in their fight, he and Jeanie decided to seek a second opinion from a critical care pulmonary specialist. This new doctor confirmed Jeanie’s IPF diagnosis, but much to the couple’s delight he explained that there were treatment options available – and that she may even become strong enough for a lung transplant down the road. “We cried tears of joy,” said Elfie. “This doctor had given us hope that we could do something. We had options.”

In March of 2016, Jeanie began taking Ofev^® (nintedanib) capsules, a treatment that the critical care pulmonary specialist explained might help slow the progression of her disease by decreasing the decline in lung function.

Today, Jeanie continues to make strides and has learned to embrace a new way of living – less active than at the peak of her pickleball-playing days, but nonetheless she leads a full life. She has started to incorporate slow walks and time in the resort’s pool into her weekly fitness routine – and the couple is looking forward to getting back on the road with an upcoming trip to their beloved home state of Washington.

“Do I wish I could still play pickleball? You bet I do. Do I dwell on it? No. Life presents you with roadblocks; my husband and I call them ‘new chapters.’ In this new chapter, I’m thankful I can do the things that I can,” Jeanie shares. “I don’t know if it’s the love around me, my positive attitude, or my will to beat this disease, but I hold onto hope. No matter how bad it looks or how bleak the day is, I never give up hope.”

To learn more about Ofev^® visit www.Ofev.com.

What is Ofev?

Ofev is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF). It is not known if Ofev is safe and effective in children.

Important Safety Information

What is the most important information I should know about Ofev^® (nintedanib)?

Ofev can cause harm, birth defects or death to an unborn baby. Women should not become pregnant while taking Ofev. Women who are able to become pregnant should have a pregnancy test before starting treatment and should use birth control during and for at least 3 months after your last dose. If you become pregnant while taking Ofev, tell your doctor right away.

What should I tell my doctor before using Ofev?

Before you take Ofev, tell your doctor if you have:

• liver problems
• heart problems
• a history of blood clots
• a bleeding problem or a family history of a bleeding problem
• had recent surgery in your stomach (abdominal) area
• any other medical conditions.

Tell your doctor if you:

• are pregnant or plan to become pregnant.
• are breastfeeding or plan to breastfeed. It is not known if Ofev passes into your breast milk. You should not breastfeed while taking Ofev.
• are a smoker. You should stop smoking prior to taking Ofev and avoid smoking during treatment.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements such as St. John’s wort.

What are the possible side effects of Ofev?

Ofev may cause serious side effects.

TELL YOUR DOCTOR RIGHT AWAY if you are experiencing any side effects, including:

• Liver problems. Unexplained symptoms may include yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests regularly to check how well your liver is working during your treatment with Ofev.
• Diarrhea, nausea, and vomiting. Your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have these symptoms, if they do not go away, or get worse and if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements.
• Heart attack. Symptoms of a heart problem may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.
• Stroke. Symptoms of a stroke may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.
• Bleeding problems. Ofev may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal and/or if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.
• Tear in your stomach or intestinal wall (perforation). Ofev may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.

The most common side effects of Ofev are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

These are not all the possible side effects of Ofev. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/Safety/MedWatch/default.htm or call 1-800-FDA-1088.

For full prescribing Information, including Patient Information, visit Ofev.com or contact Boehringer Ingelheim Pharmaceuticals at 1-800-542-6257.

2018-08-28T11:01:00

(BPT) – Every month, nearly 19 million Americans take an “omega-3,” or “fish oil” dietary supplement¹ that may include a mixture of DHA, EPA, saturated fats and other ingredients.^2-7 In fact, omega-3s are the most-used dietary supplement in the U.S.¹ Since many users are looking for heart health and other unproven benefits that go beyond simply supplementing their diets, it’s important to understand some myths and facts about these popular products.

Myth: All omega-3 products are created equal.

Fact: The process by which omega-3s are properly produced is extensive and complex. This leads to great variation from product to product. The content of most common fish oil products includes only 30 percent omega-3 and may include other unwanted ingredients including saturated fats and toxins. Also, if they aren’t handled properly, they may become spoiled. These unwanted and spoiled ingredients may lead to potential health risk.^5-7 Fish oil dietary supplements are not interchangeable with a prescription medication and are not intended or approved by the FDA to treat any medical condition.⁸

Myth: Omega-3 dietary supplements improve cardiovascular health.

Fact: There has been no conclusive proof, to date, that getting omega-3s from common fish oil dietary supplements has a positive effect on cardiovascular health in patients at risk.^9-10 Dietary supplements, unlike prescription drugs, are not intended to treat any medical condition.

Myth: Fish oil dietary supplements that are available without a prescription at pharmacies and grocery stores are reviewed by the FDA for safety and efficacy.

Fact: Fish oil dietary supplements are regulated as food, not drugs. They are not approved by the FDA to treat patients with medical conditions. Dietary supplements are not required to provide the same stringent clinical proof as drugs, including over-the-counter prescription drugs (dietary supplements are not over-the-counter drugs).¹¹

Myth: Omega-3 products aid in lowering LDL-cholesterol (aka bad cholesterol).

Fact: Most omega-3 dietary supplements contain DHA, which may increase bad cholesterol in some people.³ The effect of this increase on cardiovascular health and safety has not been extensively studied.

Myth: Omega-3 dose levels are not important.

Fact: The content of most common fish oil dietary supplements is only 30 percent omega-3. Taking a few of these capsules provides a very low daily dose of omega-3. Taking this amount has not been conclusively proven to provide any cardiovascular benefit.¹²

Myth: You can get the same amount of omega-3 in a prescription by taking more fish oil capsules.

Fact: Increasing the number of capsules you take has not been shown to provide the same amount of omega-3 as taking a prescription. Prescription omega-3 products are different from dietary supplements in many ways, including purity, stability, clinical effect, safety and FDA review and oversight. The content of supplement products varies, particularly with respect to EPA (the active ingredient in one patented prescription drug is pure EPA) the molecular structure and clinical effect of which has been shown to be unique from other forms of omega-3. Labeling of drugs is FDA approved. Labeling of dietary supplements, however, is created by the manufacturers of the supplement. Calling them “prescription grade” or “clinical grade” on their labels is not an FDA recognized standard and does not make them the same as a drug. Dietary supplements are not intended to treat serious medical conditions. The effect and safety of taking dietary supplements at high dose levels is unknown.

“I often get questions from my patients about the best ways to improve their heart health, and if a supplement is right for them,” said Dr. Ann Marie Navar, Assistant Professor of Medicine at the Duke Clinical Research Institute. “For people at an increased risk of cardiovascular disease – such as those who are overweight, have diabetes or smoke — it’s important to speak with your doctor about the right course of treatment.”

References

1. National Institutes of Health. National Center for Complementary and Integrative Health. Most Used Natural Products. Available at: https://nccih.nih.gov/research/statistics/NHIS/2012/natural-products/omega3. Accessed August 8, 2018.
2. Bradberry JC, Hilleman DE. Overview of omega-3 fatty acid therapies. P&T. 2013;38(11):681-691.
3. Kleiner AC, Cladis DP, Santerre CR. A comparison of actual versus stated label amounts of EPA and DHA in commercial omega-3 dietary supplements in the United States. J Sci Food Agric. 2015;95(6):1260-1267.
4. Ritter JC, Budge SM, Jovica F. Quality analysis of commercial fish oil preparations. J Sci Food Agric. 2013;93(8):1935-1939.
5. Mason RP, Sherratt SC. Omega-3 fatty acid fish oil dietary supplements contain saturated fats and oxidized lipids that may interfere with their intended biological benefits. Biochem Biophys Res Commun.2017;483(1):425-429.
6. US Food and Drug Administration. Letter responding to health claim petition dated June 23, 2003 (wellness petition): omega-3 fatty acids and reduced risk of coronary heart disease (docket no. 2003Q-0401). http://?wayback.archive-it.org?/7993?/20171114183726/?https://?www.fda.gov/?Food/?Ingredients?Packaging?Labeling?/LabelingNutrition?/ucm072936.htm. Published September 8, 2004. Accessed August 8, 2018.
7. Department of Health and Human Services. 21 CFR Part 184 [docket no. 86G-0289]: substances affirmed as generally recognized as safe: menhaden oil. Federal Register. June 5, 1997;62(108):30751-30757.
8. Hilleman D, Smer A. Prescription omega-3 fatty acid products and dietary supplements are not interchangeable. Manag Care. 2016;25(1):46-52.
9. Aung T, Halsey J, Kromhout D, et al. Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease RisksMeta-analysis of 10 Trials Involving 77?917 Individuals. JAMA Cardiol.2018;3(3):225–234. doi:10.1001/jamacardio.2017.5205
10. Abdelhamid AS, Brown TJ, Brainard JS, Biswas P, Thorpe GC, Moore HJ, Deane KHO, AlAbdulghafoor FK, Summerbell CD, Worthington HV, Song F, Hooper L. Omega 3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews 2018, Issue 7. Art. No.: CD003177. DOI: 10.1002/14651858.CD003177.pub3.
11. FDA 101: Dietary Supplements. Available at: https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm050803.htm/ Accessed August 8, 2018.
12. Selecting an omega-3 product for therapeutic use: an opportunity to educate patients. Pharmacy Times website. http://www.pharmacytimes.com/publications/ issue/2016/december2016/r817_december2016. Accessed August 8, 2018.

AMRN-00274 08/2018

2018-08-28T15:25:00

(BPT) – There it is again. That pain in your side that comes and goes. Not sure what to do about it? How about talking about your symptoms with a health care professional from the comfort of your own couch?

Today, the doctor’s office isn’t the only place to go to get your medical questions answered. In fact, you may not need to go anywhere. Since convenience and options are important to many of us, most health plans offer choices on how and where to access medical information and care.

Phone lines staffed by nurses. Many health plans offer access to a telephone-based support line staffed 24/7 by registered nurses — often referred to as “24/7 nurse lines” or “nursing hotlines.” The nurses take note of your symptoms. Together, you can discuss next steps and there is typically no additional charge to use this service.

Online or “virtual” office visits. Some Medicare plans allow you to visit with your doctor without leaving your living room. The clinician uses a computer or mobile device with a camera to see and talk with you. These visits sometimes even allow physicians to bring in specialists, also by computer, if needed. While in-office visits may still be the best options when it comes to serious illnesses, virtual visits work well for follow-ups and for more common illnesses and injuries like colds, flu, rashes, etc. In some states, online doctors can write and submit prescriptions after a virtual consultation. If covered, these visits may be subject to a copay or coinsurance.

In-home visits by a health practitioner. You may remember the days when doctors made home visits. Today’s in-home clinicians are often nurse practitioners (NPs) or physician assistants (PAs) who spend 45 to 60 minutes with each patient. They review your health history and current medications, perform a physical exam, offer health education and coordinate care with your primary care provider. The visit allows the health practitioner to spend a great deal of time with you in an environment where you are comfortable. They are so popular that UnitedHealthcare’s HouseCalls program recently completed its 5 millionth home visit.

These care options are not just convenient, they can also save lives. A simple urine test that Paul Engwall completed during his first HouseCalls visit led to the discovery of an abdominal aortic aneurysm that was nearing rupture. “There is no doubt in my mind that Paul’s HouseCalls visit very likely saved his life,” said his wife, Lorna. “Now we tell everyone we know about this program; we are so grateful.”

So the next time you want to speak with someone about a medical issue, pick up your phone or tablet, get comfortable and dial up the personalized support you want.

To find a UnitedHealthcare plan that offers these services, visit UHCMedicareSolutions.com.

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Plans are insured through UnitedHealthcare Insurance Company or one of its affiliated companies. For Medicare Advantage and Prescription Drug Plans: A Medicare Advantage organization with a Medicare contract and a Medicare-approved Part D sponsor. Enrollment in these plans depends on the plan’s contract renewal with Medicare.

This information is not a complete description of benefits. Contact the plan for more information. Limitations, copayments, and restrictions may apply. Benefits may change on January 1 of each year.

2018-08-28T07:03:00

(BPT) – Life can get hectic. While it is easy to become overwhelmed with busy schedules and everyday challenges, it is important to carve out personal time for relaxation and renewal. The practice of self-care and personal wellness is becoming a trend on the rise.

To incorporate this trend into your daily routine, take a page from the luxury hotel playbook. Imagine what you would see, feel, smell and experience if you stepped into the bathroom of a five-star suite. Luxury bathrooms are designed to invite you to slow down, relax and spoil yourself.

Instead of thinking of your bathroom as your “hurry-up-and-get-ready space,” transform it into a “shut-out-the-world-and-recharge-your-batteries-space.” These are some luxury hotel concepts you can implement in your own home.

Draft your color theory

Soft and subtle or deep and bold? It depends on how you want to set the mood. Soothing colors that call back to natural scenery, like seafoam greens, pale blues and soft sandstones, are relaxing. Yet rich, supersaturated colors are on-trend and can create the perfect backdrop to make chrome fixtures, sculptural appliances and other statement pieces stand out.

Indulge in upgraded essentials

Nothing speaks to luxury like thoughtfully designed bathroom products that are beautiful to look at and deliver an incomparable user experience. For example, TOTO’s elegant line of NEOREST NX Intelligent Toilets take pampering to the next level. These smart toilets feature high-tech innovations like an auto-open/close seat and lid, and a unique, integrated personal cleaning system that leaves you feeling clean and refreshed. The high-luxe NEOREST NX line is also environmentally sustainable, reducing the need for toilet paper and automatically keeping the bowl pristine without harsh chemicals thanks to their ACTILIGHT, EWATER+, and CEFIONTECT cleansing technologies. To learn more about these beautiful intelligent toilets, visit totousa.com.

Provide an extra blast of warmth

Heated flooring makes the transition from tub to toweling off pleasant, leading to a relaxing bathroom experience. For an extra touch of luxury, install a bathroom fireplace and take additional time to let your troubles melt away in the warmth and flickering light.

Don’t shy away from glamorous lighting

When adding finishing touches, try installing a great chandelier to create a focal point for the bathroom. A sparkly overhead chandelier throws light-scattering dazzle around the room, while a bold pendant light fixture adds color and clean lines. Dimming switches will give you the option to create your desired mood lighting.

Dress it up with blooms and greenery

A beautiful plant or a vase of fresh flowers will dress up any room. Research shows that the simple act of incorporating nature into your everyday life elevates the mood, making “me time” in the bathroom much more enjoyable. Opt for plants that thrive on humidity and natural light, such as orchids, ferns, bamboo and aloe vera.

Make it multisensory

When creating the ultimate luxury bathroom space, consider all five senses. Create a visually stunning scenery. Splurge on plush towels that caress your skin. Install overhead speakers to fill your ears with natural sounds or soothing music. Incorporate scents that make you feel happy and relaxed. Set up a reed diffuser or arrange scented bath bombs on a beautiful platter. And to end your day peacefully, treat yourself to a nice cup of herbal tea.

Now that you know what’s essential in a luxury-grade bathroom, take the first step in bettering your self-care routine by making transformations to your bath space.

2018-08-24T15:03:00

(BPT) – Did you know that approximately 6.4 million children in the U.S. have been diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) in their lifetime?^1* With ADHD Awareness Month coming up in October, what better time to learn more about this chronic mental disorder and debunk some myths about ADHD? Below are some common misperceptions about ADHD and five fast facts that may surprise you.

Myth: ADHD isn’t a serious or real disorder.

ADHD can be a chronic mental disorder characterized by the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5^®) and includes the core symptoms of inattention, hyperactivity and impulsivity.² ADHD is commonly referred to as AD/HD and ADD, although the correct term is ADHD.

Myth: ADHD is an “excuse.”

This is not the case. In fact, ADHD is a real disorder that can cause challenges at home, school/work or in social situations.²

Myth: ADHD only affects men, not women.

While ADHD is more frequent in men than women within the general population, women are more likely to primarily have symptoms of inattention than men.²

Myth: ADHD is a “kid’s disorder.”

While an estimated 11 percent (6.4 million) of U.S. school-aged children have been diagnosed with ADHD in their lifetime,^1* 4.4 percent of adults are estimated to have ADHD as well. When this number is applied to the full U.S. adult population (aged 18 and over), approximately 10.5 million adults are estimated to have ADHD in the U.S.^3,4,† Furthermore, in approximately 50 to 66 percent of children with ADHD, the symptoms may continue from childhood into adulthood.^5,6,7

Myth: ADHD is curable.

While there is currently no cure for ADHD, there are a variety of treatment options, both medication and non-medication alternatives, available that may help to manage the symptoms. If you think you or someone you know may have ADHD, speak to your healthcare professional about what treatment options may be right for you.

One treatment option is VYVANSE^® (lisdexamfetamine dimesylate), the #1 prescribed branded ADHD medication approved for ADHD patients 6 and older. Medication may not be appropriate for all patients. Individual results may vary so to learn more about Vyvanse and whether it could be right for you, talk to your doctor and visit www.vyvanse.com.

VYVANSE^® (lisdexamfetamine dimesylate) is a prescription medicine used for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in patients 6 years and above. It is not for weight loss. It is not known if Vyvanse is safe and effective for the treatment of obesity.

Vyvanse is a federally controlled substance (CII) because it can be abused or lead to dependence. Keep Vyvanse in a safe place to prevent misuse and abuse. Selling or giving away Vyvanse may harm others and is against the law. See below for continued safety information.

Vyvanse Capsules are currently available in seven once-daily strengths (10mg, 20mg, 30mg, 40mg, 50mg, 60mg, and 70mg). Vyvanse Chewable Tablets are currently available in six once-daily dosage strengths (10mg, 20mg, 30mg, 40mg, 50mg, and 60mg). To learn more about Vyvanse and for the Medication Guide and Full Prescribing Information, talk to your doctor and visit www.vyvanse.com, or call toll-free at 1-800-828-2088.

IMPORTANT SAFETY INFORMATION

Vyvanse is a stimulant medicine. Tell the doctor if you or your child have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

Who should not take Vyvanse?
Do not take Vyvanse if you or your child are:

• taking or have taken an anti-depression medicine called a monoamine oxidase inhibitor (MAOI) within the past 14 days.

• sensitive or allergic to, or had a reaction to other stimulant medicines.

Serious problems can occur while taking Vyvanse. Tell the doctor:

• if you or your child have heart problems, heart defects, high blood pressure, or a family history of these problems. Sudden death has occurred in people with heart problems or defects taking stimulant medicines. Sudden death, stroke and heart attack have happened in adults taking stimulant medicines. Your doctor should check you or your child carefully for heart problems before starting Vyvanse. Since increases in blood pressure and heart rate may occur, the doctor should regularly check these during treatment. Call the doctor right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Vyvanse.

• if you or your child have mental (psychiatric) problems, or a family history of suicide, bipolar illness, or depression. New or worse behavior and thought problems or new or worse bipolar illness may occur. New psychotic symptoms (such as seeing or hearing things that are not real, believing things that are not true, being suspicious) or new manic symptoms may occur. Call the doctor right away if there are any new or worsening mental symptoms or problems during treatment.

• if you or your child have circulation problems in fingers and toes (peripheral vasculopathy, including Raynaud’s phenomenon). Fingers or toes may feel numb, cool, painful, sensitive to temperature and/or change color from pale, to blue, to red. Call the doctor right away if any signs of unexplained wounds appear on fingers or toes while taking Vyvanse.

• if your child is having slowing of growth (height or weight). The doctor should check your child’s height and weight often while on Vyvanse, and may stop treatment if a problem is found.

• if you or your child have symptoms of serotonin syndrome: agitation, hallucinations, coma, or changes in mental status; problems controlling movements or muscle twitching, stiffness, or tightness; fast heartbeat; sweating or fever; nausea, vomiting or diarrhea. Call your doctor or go to the emergency room if symptoms occur. Serotonin syndrome may occur if Vyvanse is taken with certain medicines and may be life-threatening.

• if you or your child are pregnant or plan to become pregnant. It is not known if Vyvanse may harm your unborn baby.

• if you or your child are breastfeeding or plan to breastfeed. Do not breastfeed while taking Vyvanse. Talk to your doctor about the best way to feed your baby if you take Vyvanse.

What are possible side effects of Vyvanse?
The most common side effects of Vyvanse in ADHD include:

anxiety	dry mouth	trouble sleeping
decreased appetite	irritability	upper stomach pain
diarrhea	loss of appetite	vomiting
dizziness	nausea	weight loss

For additional safety information, click here for the Medication Guide, including Boxed WARNING regarding Potential for Abuse and Dependence, and discuss with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

2018-08-22T12:01:00

(BPT) – Anyone who has been affected by cancer knows that facing the disease takes enormous personal strength. Each day can present new challenges and obstacles, and it’s easy to start to feel powerless.

Dak Prescott, quarterback of the Dallas Cowboys, had to find an inner power when he lost his mother to cancer. Inspired by his family’s experiences, he teamed up with Bristol-Myers Squibb to educate people about advances in cancer research, including Immuno-Oncology (I-O).

I-O research seeks to harness the power of the body’s own immune system to help fight cancer. An important new area of I-O research is exploring biomarkers – individual characteristics of each person’s cancer. By understanding immune biomarkers, researchers may be able to help personalize care for those living with the disease.

That’s just one thing Dak Prescott wants you to know about I-O research. Here are five more facts to empower people to better understand both cancer and I-O research.

1. Cancer cells can sneak past natural defenses

Cancer cells can trick the immune system by escaping and deactivating immune cells. If the immune system doesn’t recognize cancer cells as a threat, they can survive and grow into a tumor.

2. Each person’s body is unique – and so is their cancer

Most people already know that their body is different from everyone else’s. What they might not realize is that their cancer is, too. The differences between each person’s cancer, deep down at cellular and molecular levels, give scientists and doctors important information.

3. Researchers can learn more about an individual’s cancer through biomarkers

Biomarkers are biological molecules found in blood, other bodily fluids or tissues that are signs of a normal or abnormal process or of a condition or disease. Understanding a tumor’s unique makeup through biomarkers may help researchers predict how well someone may respond to certain treatments.

4. The power of your immune system can also be harnessed to help fight cancer

The immune system constantly works to find and destroy abnormal cells, but sometimes “sneaky” cancer cells can get away. I-O research looks at how to help the immune response do what it is supposed to do – fight disease. The ultimate goal of I-O research is to improve survival and the quality of life for people living with cancer.

5. You can join the fight against cancer by participating in Ready. Raise. Rise.

To raise awareness about I-O research, Bristol-Myers Squibb is encouraging individuals to participate in the Ready. Raise. Rise. movement, alongside Dak Prescott and many others who have been impacted by cancer. Join the photo-sharing challenge and learn more about I-O research by visiting ReadyRaiseRise.com, where you can find all applicable rules and guidelines.

Content is brought to you by Bristol-Myers Squibb

2018-08-21T07:01:00

(BPT) – –

2018-08-17T13:30:00

(BPT) – Haiti has among the highest rates of elephantiasis (lymphatic filariasis), which attacks the lymphatic system, leading to abnormal enlargement of body parts, disfigurement, pain, disability and social ostracism. The World Health Organization estimates that 856.4 million people in 53 countries remain threatened by the condition.

The Haitian population also suffers from widespread iodine deficiency. The Haitian Ministry of Health has established a goal to completely eradicate elephantiasis and iodine deficiency disorders in Haiti by 2020. Fortunately, there is a simple cure for these conditions: salt fortified with iodine and diethylcarbamazine citrate (DEC).

Iodine is an essential element for healthy human life, enabling the function of thyroid glands to produce needed hormones for proper metabolism. When children in the womb don’t get enough iodine from their mother, fetal brain development is impaired. During pregnancy, iodine deficiency can cause a child to develop learning and intellectual disabilities as well as developmental problems affecting speech, hearing and growth.

“Iodine deficiency disorder (IDD) is the single greatest cause of preventable mental retardation,” says Kul Gautam, the former deputy executive director of UNICEF. “Severe deficiencies cause cretinism, stillbirth and miscarriage. But even mild deficiency can significantly affect the learning ability of populations. Scientific evidence shows alarming effects of IDD. Even a moderate deficiency, especially in pregnant women and infants, lowers their intelligence by 10-15 IQ points.”

Kiwanis International, a worldwide service organization in more than 82 nations and geographic areas, partnered with UNICEF in a global effort to eliminate iodine deficiency disorders (IDD). In just 10 years, starting in 1990, the percentage of the world population consuming iodized salt went from 20 percent to 70 percent. Kiwanis ultimately provided nearly $105 million to protect children from preventable mental and physical disabilities.

“There is no reward greater in life than helping children, and seeing them live healthy, vibrant lives. Our clubs and members understand the importance of helping children in their communities, and in communities around the world, and have proudly contributed to protecting more than 80 million children from the devastating effects of iodine deficiency,” said Stan D. Soderstrom, executive director of Kiwanis International, during a Kiwanis sponsored presentation at the 2018 World Salt Symposium in Park City, Utah.

Iodine deficiency was a problem in the U.S. as well, until American salt producers started adding iodine to table salt more than a century ago. Today, about 70 percent of the table salt sold in the U.S. is iodized. In fact, salt has been and remains the primary source for iodine in the American diet. The effect of this public health initiative has been to virtually eliminate the incidence of thyroid related illness, including goiters. “Iodized salt has been one of the greatest and most economical public health successes and it continues to help raise healthy, smart children,” said Lori Roman, President of the Salt Institute, which hosted the 2018 World Salt Symposium.

2018-08-16T09:31:00

(BPT) – Gone are the days of plumped-up puckers, ski-sloped noses, overfilled cheeks and wind-tunnel faces that were obviously “done.” Today, facial plastic surgery is about looking like the best version of yourself — refreshed, relaxed and natural.

Celebrities are driving this trend. Reality-star-turned-make-up-mogul Kylie Jenner recently announced that she had fillers dissolved from her signature pout, according to Allure, revealing natural, shapely lips. But this new trend is not just about reversing overly done procedures. It’s also about avoiding the over-done look in the first place.

As many as one-third of facial plastic surgeons report that the “fear of looking unnatural” is a top concern among cosmetic surgery patients today, according to the latest annual survey by the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS). The good news is that subtle improvements are increasingly possible, due to advances in techniques and technologies perfected by specially trained facial plastic surgeons.

“The priority to look natural continues to gain popularity, especially as more treatment options, both surgical and non-surgical, are available to patients,” says facial plastic surgeon and AAFPRS Board Member Dr. Patrick Byrne, director of the Division of Facial Plastic and Reconstructive Surgery at Johns Hopkins University.

Topping the list of facial plastic surgery procedures that restore natural beauty are eyelid lifts that rejuvenate tired-looking eyes. Facelifts have also come a long way. It’s no longer about pulling back tissue — instead, facial plastic surgeons lift and reposition underlying facial muscles to avoid a tight, pulled, wind tunnel look, and are able to minimize scarring and downtime in the process.

Even minimally invasive facial procedures such as neuromodulators and fillers are now injected in ways and amounts that create natural youthful-looking results and contours, avoiding a frozen or puffy look.

“When used correctly, injectables, such a BOTOX^® Cosmetic and hyaluronic acid fillers, can deliver a very natural result. Patients should be careful to choose an experienced injector and a board-certified facial plastic surgeon who specializes in the face, head and neck to ensure the most successful, natural-looking outcomes,” shares AAFPRS president and facial plastic surgeon Dr. William H. Truswell. “The result is not permanent and aging continues over time, as it does with any rejuvenation procedure.”

Pre-juvenation, or getting a head start on the aging process by stopping wrinkles and other signs of facial aging in their tracks, can forestall the need for more invasive facial plastic surgeries. In fact, more than half of AAFPRS members saw an increase in cosmetic procedures in those under age 30 last year.

Choosing a board-certified facial plastic surgeon is the best way to assure natural-looking results and avoid an overly done look or the need for reversal procedures. The AAFPRS is the world’s largest specialty association for facial plastic surgery, and all 2,500 members are board certified by a specialty board recognized by the American Board of Medical Specialties.

Start your search for a facial plastic surgeon at https://www.aafprs.org/patient/finder/finder.cfm.

2018-08-14T10:19:00

(BPT) – AUVI-Q^® (epinephrine injection, USP) is still available by prescription for children with life-threatening allergies.

Most kids spend the final weeks of summer amassing school supplies and cramming through summer reading lists. For children with life-threatening allergies and their parents, this time is also spent preparing for the challenge of navigating school cafeterias, packed classrooms and after-school programs.

An important part of that preparation often involves securing a prescription for an epinephrine auto-injector (EAI) before the first day of school. EAIs are used to treat life-threatening allergic reactions, including anaphylaxis. They do not take the place of emergency medical care, but are critical and potentially life-saving in an allergic emergency, so many parents and children prefer to keep a set at school.

However, some families are having trouble filling their EAI prescriptions this back-to-school season. In May, the U.S. Food and Drug Administration (FDA) reported that manufacturing delays caused an ongoing supply constraint for several EAI manufacturers, including authorized generic versions of the medication.

One EAI not experiencing any supply issues is AUVI-Q^® (epinephrine injection, USP). It is developed by kaléo using a high-tech, 100% automated robotic production line and is FDA-approved in three doses: AUVI-q 0.1 mg for infants and toddlers weighing 16.5 lbs to 33 lbs, AUVI-Q 0.15 mg for children weighing 33 lbs to 66 lbs, and AUVI-Q 0.3 mg for anyone weighing 66 lbs or more.

AUVI-Q is the only EAI with an innovative electronic voice instruction system and visual cues that guide users step-by-step through the administration process. It’s been voted the number one prescribed branded EAI by allergists.¹

AUVI-Q is not always available at local pharmacies, but kaléo is able to fill, and is filling, all order requests through their Direct Delivery service at www.auvi-q.com. So if a doctor prescribes you AUVI-Q, it can be shipped directly to your doorstep quickly. If you have commercial insurance and use the Direct Delivery service, you can get AUVI-Q for $0 out-of-pocket. Please see full terms and conditions: https://www.auvi-q.com/getting-auvi-q/. It’s important to note that patients must obtain AUVI-Q through the Direct Delivery service to ensure delivery to their home or healthcare provider’s office and the best expiration dating for AUVI-Q.

Not all pharmacies are experiencing a shortage of the more common EAIs, but knowing the alternatives before the school year begins is more important now than ever. A study published in 2017 determined that children are increasingly being treated for anaphylaxis, with an estimated 130 percent increase in emergency room visits for anaphylaxis among children four years old and younger between 2005 and 2014.²

A recent survey of 289 parents with children who have food allergies found that >87% of parents find policies about epinephrine in the schools to be helpful. Similarly, in this same study, a majority of parents who reported that epinephrine policies were not in place felt that such policies were needed.³ Food allergies (the most common cause of anaphylaxis) affect 1 in every 13 children in the U.S.,⁴ or roughly two in every classroom.⁵

As parents and children with life-threatening allergies gear up for the challenges of another school year, finding an epinephrine auto-injector should not be one of them.

Indication

AUVI-Q^® (epinephrine injection, USP) is a prescription medicine used to treat life-threatening allergic reactions, including anaphylaxis, in people who are at risk for or have a history of serious allergic reactions.

Important Safety Information

AUVI-Q is for immediate self (or caregiver) administration and does not take the place of emergency medical care. Seek immediate medical treatment after using AUVI-Q. Each AUVI-Q contains a single dose of epinephrine. AUVI-Q should only be injected into your outer thigh, through clothing if necessary. If you inject a young child or infant with AUVI-Q, hold their leg firmly in place before and during the injection to prevent injuries. Do not inject AUVI-Q into any other part of your body, such as into veins, buttocks, fingers, toes, hands, or feet. If this occurs, seek immediate medical treatment and make sure to inform the healthcare provider of the location of the accidental injection. Only a healthcare provider should give additional doses of epinephrine if more than two doses are necessary for a single allergic emergency.

Rarely, patients who use AUVI-Q may develop infections at the injection site within a few days of an injection. Some of these infections can be serious. Call your healthcare provider right away if you have any of the following symptoms at an injection site: redness that does not go away, swelling, tenderness, or the area feels warm to the touch.

If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have more or longer lasting side effects when you use AUVI-Q. Be sure to tell your healthcare provider about all the medicines you take, especially medicines for asthma. Also tell your healthcare provider about all of your medical conditions, especially if you have asthma, a history of depression, thyroid problems, Parkinson’s disease, diabetes, heart problems or high blood pressure, have any other medical conditions, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Epinephrine should be used with caution if you have heart disease or are taking certain medicines that can cause heart-related (cardiac) symptoms.

Common side effects include fast, irregular or ‘pounding’ heartbeat, sweating, shakiness, headache, paleness, feelings of over excitement, nervousness, or anxiety, weakness, dizziness, nausea and vomiting, or breathing problems. These side effects usually go away quickly, especially if you rest. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Please see the full Prescribing Information and the Patient Information at www.auvi-q.com.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

¹ Based on IMS prescription data September 2017 – May 2018 (AUVI-Q 0.15 mg and 0.3 mg).

² Motosue, M. et al. Increasing ED visits for anaphylaxis 2005-2014 The Journal of Allergy and Clinical Immunology: In Practice (2017) 5:1, 171-175.

³ Mustafa SS, Russell AF, Kagan O, et al. Parent perspectives on school food allergy policy. BMC Pediatrics. 2018. 18:164.

⁴ United States Census Bureau Quick Facts (2016 estimates).

⁵ FARE. Food Allergy Facts and Statistics for the U.S. https://www.foodallergy.org/life-with-food-allergies/food-allergy-101/facts-and-statistics [Accessed July 2018].