Category: Brandpoint Health

2018-04-09T08:01:00

(BPT) – A Simple Blood Test Can Help Doctors Determine Your Current Likelihood of Having a Blockage in Your Heart Arteries

Obstructive coronary artery disease (CAD), also known as a blockage in the heart arteries, has many telltale signs. Chest discomfort. Heartburn. Tightness or pressure in the throat, jaw, shoulder, abdomen, back or arm. Yet all these signs can signal other issues going on inside the patient. Too much spicy food, stress, a pulled muscle. The list can grow rather long. Determining the cause of these symptoms can be tricky business. So how do you and your doctor correctly identify the cause of your specific symptoms? It can be as easy as a simple blood test.

Understanding the results of the blood test is just as easy as getting the blood test done. This simple blood test is scored on a scale of 1-40. Those with low scores, defined as ≤ 15, can be safely assessed as having symptoms unlikely to be caused by CAD, whereas patients with higher scores have a higher likelihood of CAD. Patients with low scores can be spared invasive and potentially risky cardiac tests and procedures, while those with higher scores can receive additional testing necessary to achieve their proper diagnosis and treatment.

Recently, the results of the registry study, called PRESET,¹ looked at how effective the test does what it was designed to do. This simple blood test minimized unnecessary cardiology referrals and additional cardiac testing for low-risk patients. This means reducing patient exposure to radiation from a nuclear stress test or coronary CT scan, decreased likelihood of skin rashes where electrodes are placed for echocardiograms, electrocardiograms, exercise stress tests and more, reduced risk of dye reactions or risk associated with surgical heart procedures such as possible injury to the artery, kidney damage, bleeding complications, and more. These patients can get reliable information without the risks of the traditional tests.

The test (known as the Corus^® CAD blood test) incorporates age, sex and gene expression measurements into a single score that indicates a person’s current likelihood of obstructive CAD. Unlike a genetic test, which provides information about a patient’s future risk of disease, this test provides the current likelihood of blockage in his or her heart artery. It’s much safer for the patient and has the benefit of saving the healthcare system money by reducing unnecessary tests and procedures.

Recently, the American Heart Association highlighted the Corus CAD test in a new 2017 Scientific Statement² about how precision medicine can be used to diagnose and predict cardiovascular disorders. The AHA’s statement confirms that this simple blood test has been proven valid and useful in clinical studies. If you are concerned about the symptoms of obstructive CAD, talk with your doctor.

For more information about the Corus CAD blood test, visit www.corusCAD.com.

Fast Facts

• One in seven deaths among Americans is caused by CAD³
• Traditional tests carry various risks
• A simple blood test called Corus CAD helps doctors identify patients who are at low risk so that unnecessary and potentially harmful cardiac tests can be avoided, as well as those at high risk so appropriate next steps can be taken

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¹ Ladapo JA, Budoff M, Sharp D, et al. Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease. Am J Med. 2017;130(4):482.e11-482.e17.

² Musunuru K, Ingelsson E, Fornage M, et al. The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association. Circ Cardiovasc Genet. 2017;10(4):e1-e25.

³ Benjamin EJ, Blaha MJ, Chiuve SE, et al. On Behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics – 2017 Update: A Report from the American Heart Association. Circulation. 2017;135(10):e146-e603.

2018-04-03T10:01:00

(BPT) – Can cutting back on whole grains be bad for your gut and deadly to your health? Though some popular diets promote the elimination of grains, a recent report from the American Institute for Cancer Research suggests this may be ill-advised.

Researchers say 47 percent of colorectal cancers can be prevented with lifestyle changes, such as adding whole grains to your diet and exercising more. Eating three daily servings of whole grains reduces the risk of colorectal cancer by 17 percent, the report says.

But the link between whole grains and cancer may be confusing. After all, the major benefit of whole grains is fiber, and fiber is fiber, right?

Here’s the paradox about fiber: Americans have increased their consumption of fiber, including whole grains. In spite of that, bowel cancer is still one the most common types of cancer. Not all fiber is alike. Understanding how whole grains and their fiber types go to work in the gut may hold the key to reducing the risk of colorectal cancer.

A new kind of super-grain

First, we turn to the humble barley grain. It may be on the verge of a big moment. Australian researchers spent 30 years breeding a variety of barley that contains more of the properties believed to reduce colon cancer. The result is a so-called super-grain called BARLEYmax.

What’s special about BARLEYmax? This non-GMO grain has twice the fiber as most other whole grains, including wheat. It’s also chock-full of a unique type of fiber called resistant starch. Scientists believe resistant starch plays an important role in keeping the gut environment healthy. BARLEYmax has four times as much resistant starch as wheat and oats, and scientists believe it’s this resistant starch that may be the key link to fighting colorectal cancer.

What do resistant starches do?

Why did the Australian researchers want to develop a grain that was high in resistant starches? Dr. David Topping, who headed the research team, points to previous research showing the link between diet and colorectal cancer.

Africans have a lower fiber intake compared to Americans and Australians, yet their bowel cancer rates are much lower, he reports. On the surface, this appears to diminish the role of fiber. Here’s the kicker: The African diet is much higher in resistant starches and fermentable fibers than American and Australian diets.

According to Topping, that highlights the key determinant of better bowel health and fighting cancer is that we eat enough of the right fiber types, from whole grain sources, rather than to focus only on the amount of fiber we eat.

How do resistant starches work?

We’ve all heard about how important it is to make sure the gut is inhabited by the right kinds of bacteria. But it’s not as simple as taking a probiotic supplement or eating yogurt for breakfast. Gut bacteria need food to thrive, and that’s where resistant starches come in.

In the gut, resistant starches are a food source for healthy gut bacteria, and these bacteria keep the gut environment healthy. When diets are low in resistant starches, it creates a “hungry gut bacteria population.” But increasing the availability of fermentable fiber-rich whole grains that feed the gut microbiota can potentially make us healthier.

Good sources of good fiber

It’s exciting to hear that boosting your intake of resistant starches can have such a profound effect on your well-being and health. Getting the right foods that “feed” your gut has been tricky because, frankly, many are not appealing to American tastes.

Green bananas are a prime example. Although resistant starches are abundant in foods like cooked and cooled potatoes, barley and oats, these have to be eaten cold to get the full benefits, because these starches break down when heated.

Australian natural foods company Freedom Foods is the first breakfast manufacturer to bring the unique BARLEYmax grain to the U.S. under their Barley+ line of Toasted Mueslis and nutritional bars. The format, which is much closer to American-style granola but without all the sugar, will provide Americans with a much more accessible way to access resistant starch than some of the more obscure sources currently available.

Barley+ Toasted Muesli and Barley+ Snack Bars are now available at grocers and other retailers. To learn more about the mueslis and snacks, visit freedomfoodsus.com.

2018-03-29T15:01:00

(BPT) – Do you love dairy, but usually regret eating it shortly after it’s gone? That sour stomach after drinking milk, munching on cheese or eating ice cream is sometimes called a dairy hangover. The culprit: lactose.

Lactose is a milk sugar. Infants have special enzymes that break down lactose. As people grow, the ability to digest milk typically decreases because they lose these enzymes. In fact, approximately 65 percent of the human population has a reduced ability to digest milk and foods made with milk after infancy, according to the National Institutes of Health.

Symptoms of lactose intolerance

If you’ve had the following symptoms after eating dairy products, you may be lactose intolerant:

* Gas

* Bloating

* Abdominal cramping

* Diarrhea

* Nausea

If you or your children have these symptoms, there are many things you can do. First, talk with your doctor or nutritionist about your health concerns. Second, consider keeping a food journal of what you eat and how it makes you feel. This can help uncover trends and important connections. Finally, research high-quality dairy-free alternatives for you and your family’s diet.

Tips for going dairy-free

Adjusting to a low-dairy or dairy-free diet might seem overwhelming. There are many dairy-free milk options on the market, but it’s important to be a conscientious shopper. Whereas most dairy-free beverages use non-food flavorings and additives like carrageenan, all plant-based Mooala products are made with real ingredients, and are USDA-certified organic, Kosher and GMO-free.

Every Mooala product has 10 or fewer grams of sugar per serving and it can be found in approximately 1,500 retailers throughout the U.S. Try Original Almondmilk and Vanilla Bean Almondmilk for a creamy treat that tastes surprisingly similar to milk. Nut-free and soy-free Original Bananamilk is also available to the estimated 5 million Americans who are allergic to tree nuts.

Another concern for people cutting dairy is vitamin D and calcium deficiencies. Fortunately, there are foods you can add to your diet so you get these important nutrients. Egg yolks, canned tuna and almonds are good sources of vitamin D. Spinach, kale, collards and white beans are good sources of calcium. What’s more, many common grocery store items are fortified with calcium and vitamin D as well, such as breakfast cereals and orange juice. Just look at the label for more information.

There are plentiful options to eat well and go dairy-free if you have lactose sensitivities. Have fun exploring new recipes that support your nutritional needs. One that features many of these powerful dairy-free foods is a tasty smoothie you can whip up in just minutes:

Grapefruit Bananamilk Smoothie

Ingredients:
1 deseeded grapefruit
1 sweet apple
2 handfuls of spinach
1 frozen banana
1 handful of ice
1/2 cup Mooala’s Original Bananamilk
Dash of fresh ginger

Directions:
Place ingredients in blender, then puree until you’ve reached your desired consistency.

2018-04-03T14:01:00

(BPT) – If you’ve ever tried to lose weight, you probably know it can seem like an overwhelming task. In fact, a recent survey conducted by The Harris Poll indicates losing weight is harder than ever before, and that today’s busy modern lifestyle is a key reason why.

But, don’t lose hope. Results also suggest that taking a new approach to weight loss can help, and that you can increase your chances for reaching and maintaining your weight-loss goals by getting a clear picture of the factors holding you back, and establishing a plan compatible with your lifestyle.

“The Truth About Weight Loss” survey was conducted online by The Harris Poll in October/November 2017 on behalf of Zaluvida, the makers of I-REMOVE (R), and included nearly 1,000 health care professionals [458 primary care physicians (PCPs) and 503 pharmacists], and more than 1,000 U.S. adults ages 18 and over.

So, what are our roadblocks?

The survey paints a picture of U.S. adults who are discouraged when it comes to weight loss, and some of the key reasons why.

Among its findings:

* 77 percent of PCPs and 81 percent of pharmacists say losing weight is harder today than it was for previous generations because of the busy, modern lifestyle of Americans.

* Too much screen time (i.e., time spent on computers, tablets and mobile phones) has resulted in Americans leading less-active lifestyles, according to 95 percent of PCPs and 97 percent of pharmacists.

* Lack of time is taking a toll as well. 97 percent to 98 percent of PCPs and pharmacists are concerned that Americans not taking time to plan healthy meals will negatively impact their weight and their family’s weight.

The result of all this? Widespread frustration. While 41 percent of Americans are now attempting to lose weight, only 29 percent of them are confident they’ll achieve their current weight-loss goals. Fifty-nine percent of them say they’re frustrated by previous attempts to lose weight — typically, they’ve tried to slim down a substantial five times in the past five years.

What’s needed? A sustainable plan, and more weight-loss options.

At least 89 percent of health care professionals surveyed say Americans need to take a new approach to weight loss that fits with today’s modern lifestyle.

Instead of embarking blindly on a goal to lose weight, they say people should develop a plan that accounts for their potential stumbling blocks — most advise that your plan should be sustainable (79 percent of PCPs and 69 percent of pharmacists), not be time-consuming (56 percent of PCPs and 55 percent of pharmacists), and not require sudden or major shifts to your daily routine (54 percent of PCPs and 53 percent of pharmacists).

You may also want to consider new options; at least 84 percent of PCPs and pharmacists say they wish they had more weight-loss options for people who are overweight but not yet obese, and 63 percent of PCPs and 60 percent of pharmacists agree that a weight-loss product/aid that fits into one’s lifestyle without unpleasant side effects would make it easier for their patients to lose weight.

One such product that’s now available in the U.S. is I-REMOVE, a weight-loss aid aimed at helping people lose weight and achieve healthier lifestyles they can sustain long-term. As the No. 1 best-selling weight-loss formula in Europe, I-REMOVE is clinically tested and shown to help with weight loss and maintenance, and can deliver up to three times the weight loss of dieting alone. Sold in the U.S. it is available nationwide at Walgreens and other retailers.

Consult with your health care professional before embarking on any weight-loss plan.

For more survey results, visit www.weightlossfindings.com.

For more information about I-REMOVE, visit https://www.i-remove.com.

About the National Survey “The Truth about Weight Loss”

The survey was conducted online within the United States by The Harris Poll on behalf of Zaluvida between October 13 and November 6, 2017. The consumer arm of the survey included a total of 1,005 U.S. adults ages 18+, of whom, 713 are currently trying (n=429) or have ever tried (n=284) to lose weight. The professional arm of the survey included 961 U.S. adults ages 18+ who are primary care physicians (n=458) or pharmacists (n=503). For complete research method, including weighting variables and subgroup sample sizes, please contact press@i-remove.com.

2018-04-02T10:01:01

(BPT) – Approximately 2 million Americans are battling a disease that many people may not understand or feel ashamed to admit being impacted by: opioid addiction.[1] Like many other diseases, opioid addiction can be a continued struggle for afflicted individuals and for their families and caregivers.[2] People living with opioid addiction — and their loved ones — may face judgment from others who see it as a failure of will or a “choice,” and do not understand that it is a disease.[3] Because of this stigma, people battling opioid addiction may be afraid to ask for help or feel uncertain about where to find information and how treatment options along with counseling may help.

Education that opioid addiction is a disease must continue to ensure that stigma does not impede people with opioid addiction from getting the help they need. Studies have shown that the use of medication-assisted treatment (MAT) may help patients on their road to recovery because it is a combination of medication, which helps to treat the physical effects of addiction, and counseling, which helps teach people effective recovery skills.[3]

While MAT has been proven to effectively help in the treatment of opioid addiction, research has suggested it is often underutilized among healthcare professionals. In fact, fewer than 20 percent of adults with substance use disorders in the U.S., including those with opioid use disorder, receive any kind of treatment.[1]

Dr. Stephen Stahl, Adjunct Professor of Psychiatry at University of California San Diego and a contracted spokesperson for Alkermes, has pioneered the successful use of MAT and believes there are many people battling opioid addiction that may benefit from finding a treatment approach that is right for them.

“Counseling and medication each have an important role in recovery from opioid addiction. Counseling helps people understand underlying issues and effective recovery skills, while medication can help treat the physical effects of addiction. When used together, these options can be effective,” said Dr. Stahl. “Being an advocate for someone struggling with opioid addiction starts with knowing all you can about the different treatment options that may help pave the road on the recovery journey.”

Dr. Stahl recommends the following important steps for families looking for information on MAT programs:

• Understand how MAT works
  Research suggests: Counseling targets the cortex to help treat the psychological aspects of dependence. Medication targets the limbic region to help treat the physical effects of dependence.

• Explore different treatment options that may be available
  There are different types of medication used with counseling to treat opioid dependence: antagonists, agonists and partial agonists. Consult a healthcare provider for more information on selecting a treatment approach that best suits the individual’s needs.

• Learn more through the stories & experiences of others
  A new initiative called Let’s Change the Conversation provides guidance about how to start a conversation with a loved one or healthcare provider about MAT, inspirational stories from other families touched by opioid addiction as well as information about an available treatment option.

ALKERMES is a registered trademark of Alkermes, Inc. ©2018. All rights reserved. OT-001562.

2018-04-04T07:01:00

(BPT) – As a former professional football player and national sports talk show host, Mike Golic is constantly on the go. Living with type 2 diabetes means that Mike needs to take a few extra steps to manage his diabetes throughout the day. Here are a few tips that Mike uses to stay on track and find fun ways to help ensure a balanced diet and moderate exercise are part of his busy lifestyle.

Learn more about Mike’s story by visiting ICanImagine.com.

• Make healthy eating a priority. Mike knows he needs to fuel his body for the day ahead, so he always plans a healthy breakfast to help sustain his energy on and off the air. Having nutritious breakfast recipes on hand can help start the day off right. While Mike allows for the occasional indulgence, he focuses on healthy options throughout the day, stressing that moderation is key.
• Work in your workouts. After Mike gets home from co-hosting a great show, it’s time to work out. The American Diabetes Association recommends 30 minutes of moderate-to-vigorous intensity aerobic exercise at least 5 days a week, and varying the types of exercise can help. Mike’s workout plan often includes walking his dogs and going to a fitness class with running, rowing, and strength exercises.
• Lean on your support team to stay motivated. As the sun begins to set on the day, Mike enjoys relaxing with his family. Part of his diabetes management plan includes recruiting people like his family members to be his teammates, and talking with his doctor like he’s his head coach. After a busy day, Mike and his wife, Chris, team up to cook a healthy dinner together. Chris helps Mike plan ahead and stay motivated to stick to the game plan that Mike and his doctor set.
• Feel confident in your numbers. To help Mike manage his type 2 diabetes, Mike’s doctor prescribes INVOKANA^® (canagliflozin). INVOKANA^® is taken by over 1.5 million people since launch and counting to help lower their A1C numbers. Mike sees lowering his A1C numbers as a goal and a challenge, and says when he wants to improve, “I physically put my numbers somewhere, look at them, and say ‘Next time, this is going to be better!’” INVOKANA^® helps Mike feel confident about his numbers and taking it as prescribed is an important part of the game plan he created with his doctor.

INVOKANA^® is a once-daily pill used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. In most clinical trials, the majority of people taking INVOKANA^® reached an A1C goal of less than 7.0 percent, which is recommended by the American Diabetes Association. INVOKANA^® is not for weight loss, but may help people lose weight — on average 2-3 percent. INVOKANA^® was also shown in clinical trials to reduce systolic blood pressure (on average 3-5 mmHg), though it is not indicated as a blood pressure medication. Results may vary by dose and when used alone or with certain other diabetes medications. INVOKANA^® may increase a person’s risk of lower-limb amputations. The most common side effects of INVOKANA^® include genital yeast infections, urinary tract infection, and changes in urination. These specific adverse events were generally mild to moderate in intensity in clinical studies.

If you’re looking for ways to manage your own type 2 diabetes and feel confident in your numbers, visit INVOKANA.com for planning and motivation tips. Find “secrets to staying active” and browse diabetes-friendly recipes with detailed preparation directions, ingredient tips, and nutrition facts to help ensure you’re eating well. Be sure to talk to your doctor about managing your diabetes and before starting a diet or exercise program.

WHAT IS INVOKANA^®?

INVOKANA^® is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. INVOKANA^® is not for people with type 1 diabetes or with diabetic ketoacidosis (increased ketones in blood or urine). It is not known if INVOKANA^® is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

INVOKANA^® can cause important side effects, including:

• Amputations. INVOKANA^® may increase your risk of lower-limb amputations. Amputations mainly involve removal of the toe or part of the foot; however, amputations involving the leg, below and above the knee, have also occurred. Some people had more than one amputation, some on both sides of the body. You may be at a higher risk of lower-limb amputation if you: have a history of amputation, have heart disease or are at risk for heart disease, have had blocked or narrowed blood vessels (usually in leg), have damage to the nerves (neuropathy) in the leg, or have had diabetic foot ulcers or sores. Call your doctor right away if you have new pain or tenderness, any sores, ulcers, or infections in your leg or foot. Your doctor may decide to stop your INVOKANA^® for a while if you have any of these signs or symptoms. Talk to your doctor about proper foot care
• Dehydration. INVOKANA^® can cause some people to become dehydrated (the loss of too much body water), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at higher risk of dehydration if you have low blood pressure, take medicines to lower your blood pressure (including diuretics [water pills]), are on a low sodium (salt) diet, have kidney problems, or are 65 years of age or older
• Vaginal yeast infection. Women who take INVOKANA^® may get vaginal yeast infections. Symptoms include: vaginal odor, white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese), or vaginal itching
• Yeast infection of the penis (balanitis or balanoposthitis). Men who take INVOKANA^® may get a yeast infection of the skin around the penis. Symptoms include: redness, itching, or swelling of the penis; rash of the penis; foul-smelling discharge from the penis; or pain in the skin around penis

Talk to your doctor about what to do if you get symptoms of a yeast infection of the vagina or penis.

Do not take INVOKANA^® if you:

• are allergic to canagliflozin or any of the ingredients in INVOKANA^®. Symptoms of allergic reaction may include: rash; raised red patches on your skin (hives); or swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing
• have severe kidney problems or are on dialysis

Before you take INVOKANA^®, tell your doctor if you have a history of amputation; heart disease or are at risk for heart disease; blocked or narrowed blood vessels (usually in leg); damage to the nerves (neuropathy) of your leg; diabetic foot ulcers or sores; kidney problems; liver problems; history of urinary tract infections or problems with urination; are on a low sodium (salt) diet; are going to have surgery; are eating less due to illness, surgery, or change in diet; pancreas problems; drink alcohol very often (or drink a lot of alcohol in short-term); ever had an allergic reaction to INVOKANA^®; or have other medical conditions.

Tell your doctor if you are or plan to become pregnant, are breastfeeding, or plan to breastfeed. INVOKANA^® may harm your unborn baby. If you become pregnant while taking INVOKANA®, tell your doctor right away. INVOKANA^® may pass into your breast milk and may harm your baby. Do not breastfeed while taking INVOKANA^®.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take diuretics (water pills), rifampin (used to treat or prevent tuberculosis), phenytoin or phenobarbital (used to control seizures), ritonavir (Norvir^®, Kaletra^® – used to treat HIV infection), or digoxin (Lanoxin^® – used to treat heart problems).

Possible Side Effects of INVOKANA^®

INVOKANA^® may cause serious side effects, including:

• Ketoacidosis (increased ketones in your blood or urine). Ketoacidosis has happened in people who have type 1 or type 2 diabetes, during treatment with INVOKANA^®. Ketoacidosis is a serious condition, which may need to be treated in a hospital. Ketoacidosis may lead to death. Ketoacidosis can happen with INVOKANA^® even if your blood sugar is less than 250 mg/dL. Stop taking INVOKANA^® and call your doctor right away if you get any of the following symptoms: nausea, vomiting, stomach-area pain, tiredness, or trouble breathing
• Kidney problems. Sudden kidney injury has happened to people taking INVOKANA^®. Talk to your doctor right away if you: 1) reduce the amount of food or liquid you drink, if you are sick, or cannot eat or 2) you start to lose liquids from your body from vomiting, diarrhea, or being in the sun too long
• A high amount of potassium in your blood (hyperkalemia)
• Serious Urinary Tract Infections: may lead to hospitalization and have happened in people taking INVOKANA^®. Tell your doctor if you have signs or symptoms of a urinary tract infection such as: burning feeling while urinating, need to urinate often or right away, pain in the lower part of your stomach (pelvis), or blood in the urine. Some people may also have high fever, back pain, nausea, or vomiting
• Low blood sugar (hypoglycemia). If you take INVOKANA^® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take INVOKANA^®

Signs and symptoms of low blood sugar may include: headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking, or feeling jittery.

Serious allergic reaction. If you have any symptoms of a serious allergic reaction, stop taking INVOKANA^® and call your doctor right away or go to the nearest hospital emergency room.

Broken Bones (fractures): Bone fractures have been seen in patients taking INVOKANA^®. Talk to your doctor about factors that may increase your risk of bone fracture.

The most common side effects of INVOKANA^® include: vaginal yeast infections and yeast infections of the penis; changes in urination, including urgent need to urinate more often, in larger amounts, or at night.

Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Janssen Scientific Affairs, LLC at 1-800-526-7736.

Please see full Product Information, including Boxed Warning, and Medication Guide for INVOKANA^®.

Canagliflozin is licensed from Mitsubishi Tanabe Pharma Corporation. Trademarks are those of their respective owners.

076190-171006

2018-03-28T13:00:00

(BPT) – Carolyn Rios and her husband Rick have adventured far and wide together. From their post-college move to the Alaskan wilderness to 20 years of humanitarian work in Russia, this couple of more than 50 years has shared experiences that have far exceeded their imaginations.

Decades of adventure together — including a forced landing in their bush plane when its engine failed over a mountain range — have helped Carolyn and Rick learn to face and effectively manage unexpected challenges. But even as the two have come to expect the unexpected, nothing could have prepared the couple for Carolyn’s diagnosis at age 69 with the rare lung disease idiopathic pulmonary fibrosis, or IPF, in 2015.

“All of my emergency training could not equip me for the day Carolyn was diagnosed,” said Rick. “My initial thought was, ‘What do I do now? Where’s the emergency plan? How do we land this plane?’”

IPF causes permanent scarring of the lungs. It affects up to 132,000 Americans and yields about 50,000 new cases every year. A proper diagnosis for IPF patients often takes years because its symptoms, including breathlessness and a dry persistent cough, are similar to — and easily confused with — other more common and recognizable lung diseases, such as chronic obstructive pulmonary disorder (COPD) or asthma.

After Carolyn’s diagnosis, she experienced a period of deep concern for taking the next best steps — spiritually, emotionally and medically. Praying brought her comfort and clarity. Sharing the news with their two sons, family members and close friends brought support and companionship. The medical information seemed so bleak, yet her energy to pursue the next best steps remained. Thankfully, she and Rick were able to identify a pulmonologist who educated the two on Ofev^® (nintedanib), a treatment option that could help slow the progression of the disease.

Armed with information about IPF and potential treatment options, Carolyn and Rick started thinking about IPF as their next adventure and charted their course. Carolyn began taking Ofev^®, and Rick became her helper, assisting her to map out her daily regimen, track her medications and doctor appointments and follow a precise exercise and nutrition plan.

Today, Carolyn’s regular checkups have indicated only a slight drop in lung function. She experiences queasiness due to the medication but works with her doctors — her “adventure guides” — to manage this by eating certain foods prior to taking the medication.

“Life leads us on many adventures. Some adventures we plan, others are unexpected, and others challenge us more than we expect! But regardless, every adventure teaches us something if we’re willing to learn,” said Carolyn. “Experiencing IPF is another one of life’s adventures for me and accepting the challenges that come with it brings me to a deeper understanding of the true essence of my life. Each day still has opportunities to love well — with or without IPF.”

Carolyn and Rick are still able to travel together and most recently planned five trips for their 50th wedding anniversary — one trip to celebrate each decade of their adventure-packed marriage. And while their new “adventure” with IPF is ongoing, they are determined to focus instead on their time together and with their sons and grandchildren.

To learn more about Ofev^® visit www.Ofev.com.

What is OFEV?

OFEV is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF). It is not known if OFEV is safe and effective in children.

Important Safety Information

What is the most important information I should know about OFEV (nintedanib)?

OFEV can cause harm, birth defects or death to an unborn baby. Women should not become pregnant while taking OFEV. Women who are able to become pregnant should have a pregnancy test before starting treatment and should use birth control during and for at least 3 months after your last dose. If you become pregnant while taking OFEV, tell your doctor right away.

What should I tell my doctor before using OFEV?

Before you take OFEV, tell your doctor if you have:

• liver problems
• heart problems
• a history of blood clots
• a bleeding problem or a family history of a bleeding problem
• had recent surgery in your stomach (abdominal) area
• any other medical conditions.

Tell your doctor if you:

• are pregnant or plan to become pregnant.
• are breastfeeding or plan to breastfeed. It is not known if OFEV passes into your breast milk. You should not breastfeed while taking OFEV.
• are a smoker. You should stop smoking prior to taking OFEV and avoid smoking during treatment.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements such as St. John’s wort.

What are the possible side effects of OFEV?

OFEV may cause serious side effects.

TELL YOUR DOCTOR RIGHT AWAY if you are experiencing any side effects, including:

• Liver problems. Unexplained symptoms may include yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests regularly to check how well your liver is working during your treatment with OFEV.
• Diarrhea, nausea, and vomiting. Your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have these symptoms, if they do not go away, or get worse and if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements.
• Heart attack. Symptoms of a heart problem may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.
• Stroke. Symptoms of a stroke may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.
• Bleeding problems. OFEV may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal and/or if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.
• Tear in your stomach or intestinal wall (perforation). OFEV may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.

The most common side effects of OFEV are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

These are not all the possible side effects of OFEV. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/Safety/MedWatch/default.htm or call 1-800-FDA-1088.

For full Prescribing Information, including Patient Information, visit OFEV.com or contact Boehringer Ingelheim Pharmaceuticals at 1-800-542-6257

2018-04-11T07:01:01

(BPT) – Hard water, which contains high levels of calcium and magnesium, can be found in nearly 90 percent of American homes. These minerals cause scaling, a buildup that clogs waterlines and plumbing forcing appliances to work harder and operate less efficiently. The scale may also harbor bacteria. The only way to truly remove the hard and soft scale from household water systems is with salt-based water softeners.

The environmental and cost benefits of salt-based water softening are significant. Hard water scaling can cause your showerhead to lose up to 75 percent of its flow rate in just 18 months. Hard water also interacts negatively with soap, reducing its cleaning power. Soft water is up to 12 times more effective at cleaning dishes than increasing the amount of detergent used.

According to the Water Quality Research Foundation for washing machines, the most important factor in removing stains from clothing was water softness. Reduction of water hardness was up to 100 times more effective at stain removal than increasing the detergent dose or washing with hotter water. In fact, soft water can reduce soap use by as much as half. Hard water can also reduce the efficiency of water heaters and increase electricity costs by as much as 48 percent, according to the Battelle Memorial Institute.

Hard water scaling doesn’t just harm your appliances and wallet, it can harm your health as well. The piping used in home plumbing, whether it is copper or PVC, has very smooth interior surfaces that don’t permit bacteria to settle and grow. However, hard water results in scale formation on the interior surfaces of those pipes and that provides a perfect home for bacteria.

Researchers at the School of Sustainable Engineering at Arizona State University found bacteria may grow in pipes filled with both hard scale and soft scale at the same rate. This is important new information because some forms of water conditioning produce this soft scale. The only solution is to remove both hard and soft scale in the pipes with a salt-based water softener.

Hard water you use to wash your fresh fruits and vegetables may actually contain more bacteria, and the problem isn’t only in the kitchen. When you take a hot shower the steam you are inhaling can also contain the same microbial contamination that is in the rest of your plumbing, exposing you to bacteria such as Legionella, which can cause Legionnaire’s disease.

A salt-based water softener is the most functional and cost-effective means of removing hardness minerals. It is a time-tested, highly reliable tool to improve health and to lower maintenance costs for home appliances like dishwashers and washing machine. It also reduces the need for detergents and high-water temperatures, leading to a smaller household carbon footprint.

2018-04-03T09:01:00

(BPT) – Many women and their doctors are still confused about the safety of estrogen. When introduced, estrogen was believed to be good for you. But, following the Women’s Health Initiative study 15 years ago, women were told that hormone therapy could, in fact, lead to an increased risk of cancer, blood clots and heart disease. Nothing could be further from the truth, according to Dr. Mache Seibel, author of The Estrogen Fix.

Today, women are learning that use of hormone therapy (HT) can minimize risks and maximize menopausal relief for common symptoms like hot flashes, dryness, mood swings, fractured sleep, brain fog, irritability and weight gain. When taken at the right time, estrogen therapy can lead to substantial improvements in health and quality of life and lower the risk of breast cancer, heart disease, and dementia. Women should be aware of one caveat: beginning estrogen after a woman’s estrogen window closes at age 65 may increase their risk for breast cancer, heart disease, Alzheimer’s and osteoporosis.

Heeding advice about how and when to stop taking HT is important and revealed in new studies featured in Dr. Seibel’s The Estrogen Fix. The book reaffirms the safety of vaginal estrogen for the heart and brain, as well as its effectiveness in controlling weight; additionally, the book outlines newly available estrogens and progesterones, discusses misconceptions about compounded hormones and estrogen pellets and offers the latest hormone-free FDA solutions for women with vaginal dryness.

The following are 5 creative approaches to combat menopausal symptoms:

1. Hot flashes: Women experiencing hot flashes and night sweats can find relief using an FDA-approved estrogen hormone therapy called Divigel, a cool, clear gel that is applied to the upper thigh daily. It contains the plant-based estrogen hormone estradiol, the same hormone made naturally by a woman’s ovaries before menopause and delivers estrogen identical to that naturally produced in the body.

2. Irritability/sleeplessness: Quality sleep is often a challenge during menopause and can contribute to high blood pressure, diabetes, heart disease and obesity. A natural supplement with melatonin like Vitafusion Beauty Sleep promotes a good night’s sleep without prescription medication. Sex and/or self-pleasure are natural ways to decrease stress and can help with the onset and quality of sleep. The oxytocin released with hugging, stimulation and orgasm can increase feelings of calm and safety, causing cortisol levels to drop, thus optimizing sleep. Orgasm releases prolactin, helping you fall asleep faster and more efficiently.

3. Painful sex: Internal vaginal dryness can be relieved for three days with hormone-free Replens Vaginal Moisturizer. Alternatively, prescription remedies like vaginal estrogen or DHEA can be used. Don’t forget to incorporate a personal silicone lubricant like Replens Silky Smooth just before sex to ease penetration, increase comfort and reduce abrasion.

4. Weight gain? Eat to defeat menopause: Food is the fuel for every cell in your body, so avoid packaged and processed foods and limit sugary drinks and desserts to ensure you’re optimizing energy. Stick to unprocessed whole foods as there are no hidden ingredients or calories. Your body will also appreciate fresh and/or organic produce and hormone-free meat or grass-fed beef as often as possible. Eat to Defeat Menopause: The Essential Nutrition Guide for a Healthy Midlife offers practical advice and information on how to choose and prepare meals to optimize health during menopause.

5. Hair lacking luster, less-than-glowing skin and brittle nails: Loss of estrogen leaves many women dealing with thinning hair, increased dry skin and brittle or breaking nails. Introducing biotin into your diet with a raspberry-flavored gummy like Vitafusion Gorgeous Hair, Skin & Nails can ensure you’re consuming sufficient biotin and other helpful nutrients including vitamins C and E.

Every woman has safe, new options, from prescription HT to those available over-the-counter, to suit her unique needs. Schedule a chat with your health provider to discuss the right hormone therapy or alternative option for your personal menopausal challenge.