Category: Brandpoint Health

2023-06-15T08:01:00

(BPT) – New parents who either currently use or are looking to start using formula are faced with a multitude of options these days, making it hard to feel confident in choosing the right one for their baby. The research feels endless and so many formulas provide the same, if not similar, ingredients and benefits, making it difficult to land on your choice. Look for formulas that go beyond the basics to provide your child with important nutrients during a critical growth period in their lives.

Infant formulas have vitamins and minerals to support baby’s wellness — like calcium, iron and vitamin A. DHA and probiotics are also important for supporting brain development and immune health. But only one leading formula brand has lactoferrin (added as an ingredient), a key ingredient in Enspire Optimum™, making it Enfamil’s closest formula to breast milk.

What is lactoferrin?

Lactoferrin is an important protein found in breast milk and colostrum, the very early breast milk that is dense in nutrients. Lactoferrin helps support digestive and immune health for newborns during the first year of life.

What does lactoferrin do?

Clinical studies have shown lactoferrin’s ability to support immune and respiratory health for infants and toddlers, which gives parents peace of mind. It also supports gut health.

What makes Enspire Optimum special?

Through the maker of Enfamil^® formulas’ extensive research of human milk, they are able to better understand not only the nutrients in breast milk, but also the benefits of these nutrients for infants. Enfamil was able to identify a key component in breast milk that was largely absent from other formulas. Because Enfamil believes this component will help support an infant’s start in life, they created Enspire Optimum, the only leading formula with lactoferrin added as an ingredient.

This attention to detail means parents who choose to feed their child Enspire Optimum can feel confident they’re supporting their baby’s best start in life from a brand they can trust.

In addition to lactoferrin, Enspire Optimum also has a global expert-recommended amount of brain-building omega-3 DHA to support brain development and HMOs to support immune health. If you are interested in learning more about Enspire Optimum, by Enfamil, the No. 1 trusted infant formula brand by pediatricians and parents, visit Enfamil.com/enfamil-enspire/.

2023-06-15T10:29:00

(BPT) – Article is sponsored and developed by Sanofi. Nancy and Dr. Bai were compensated by Sanofi. This is not medical advice.

At 84 years old, Nancy has always been described as an active, high-energy person. With her husband, two sons, and two grandsons, her family often spends quality time hiking, fishing, and cheering on their favorite baseball team. But a few years ago, Nancy was diagnosed with a rare blood disorder that threatened the active lifestyle she cherished.

Living with Cold Agglutinin Disease (CAD)

After knee replacement surgery in 2016, Nancy’s bloodwork showed she lost an abnormally large volume of her body’s hemoglobin, a protein found in red blood cells.¹ She was referred to a hematologist who diagnosed her with cold agglutinin disease (CAD), a rare autoimmune hemolytic anemia in which the body mistakenly attacks and destroys red blood cells, also known as hemolysis.²

According to her test results, Nancy’s body was destroying red blood cells faster than replacing them. Since red blood cells are vital for carrying oxygen to organs and tissues, she quickly developed symptoms.¹

Nancy experienced sudden, overwhelming fatigue during simple daily activities like cooking, cleaning, and grocery shopping. “I found that I couldn’t even climb stairs anymore,” she said, and she no longer had the energy to help care for her friends and family.

According to Dr. Wei Bai, board certified oncologist and hematologist, fatigue is one of the most common symptoms for patients with CAD, which can significantly impact their quality of life. Other symptoms may include weakness, shortness of breath, light-headedness, chest pain, and bluish color or discomfort in the hands and feet.³

A Treatment to Take Back Control

Nancy began working with Dr. Bai in 2021, before an approved treatment for CAD was available.⁴ They tried a variety of tactics like cold avoidance and related medications, but nothing successfully maintained her hemoglobin levels. Despite growing frustrated with fatigue that continued to interfere with her daily life, she never stopped fighting. “My life wasn’t fun anymore. I wanted to get it back,” she said.

New hope for Nancy came in 2022 with the U.S. Food and Drug Administration (FDA) approval of Enjaymo^® (sutimlimab-jome), the first and only medication for adults with CAD.^4,5

Understanding the Research Behind Enjaymo

Enjaymo is a prescription medicine used to treat hemolysis in adults living with CAD. Its FDA approval is supported by findings from two Phase 3 studies: a single-arm, open-label study in patients with CAD with a recent history of blood transfusion (within the past 6 months), and a double-blind, placebo-controlled clinical trial of adults with CAD without a recent history of blood transfusion (within the past 6 months).^4,5 It is recommended that Enjaymo should not be taken by patients with known hypersensitivity to sutimlimab-jome or any of the inactive ingredients.

In one Phase 3 study, Enjaymo demonstrated fast and lasting improvement in hemoglobin levels. The trial met its composite primary endpoint – 73% of patients (16/22) showed an increase in hemoglobin of at least 1.5g/dL from baseline to Week 26 compared to 15% (3/20) on placebo, as well as remained transfusion-free from Week 5 through 26, and required no additional CAD treatment during the same time period. Additional data showed a mean increase from baseline hemoglobin levels. Further, average bilirubin levels from baseline to Week 26 returned to normal among 17 patients taking Enjaymo.^4,5

Patients taking Enjaymo also reported a significant improvement in the symptoms and impact of fatigue as measured by The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) at 6 months. In the clinical trial, patients on Enjaymo had an average 11-point improvement from baseline (improving from an average baseline score of 31.67 points to an average score at treatment assessment of 42.5 points) vs a 2-point improvement in patients on placebo. Higher scores on the survey meant a person felt less fatigue. The overall safety results were consistent with the safety profile of Enjaymo from the pivotal study.^4,5

Nancy’s Comeback from CAD with Enjaymo

Dr. Bai reviewed Nancy’s history to ensure she had or received the right vaccinations before starting Enjaymo. Together, they discussed the potential side effects of Enjaymo, including increase in blood pressure, urinary tract infection, respiratory tract infection, bacterial infection, swelling in lower legs or hands, joint pain, headache, nausea, runny nose, bluish color to the lips and skin, dizziness, feeling tired or weak, cough, changes in color or sensation in the fingers and toes (Raynaud’s phenomenon).⁵

Dr. Bai also advised Nancy on the infusions for Enjaymo, which are weekly for the first two weeks, then biweekly thereafter.⁵ She looks forward to her infusions as a time to relax, read a book, and take a few moments for herself away from daily responsibilities.

Since starting Enjaymo, Nancy’s hemoglobin has risen significantly (almost 4 g/dL) to normal levels (11.5 to 16 g/dL for women¹) and she hasn’t needed other treatments to manage her CAD. Today, Nancy reports significantly less fatigue than prior to starting Enjaymo. Once again, she has enough energy for grocery shopping, cooking, and caring for her loved ones. “I’m living the life I want with my husband, kids, grandkids, and friends,” she said, “I look forward to going to Alaska next year to fish for salmon and halibut with my family.”

Patient experiences on Enjaymo may vary so please talk to your doctor when making treatment decisions. To learn more, visit Enjaymo.com.

Important Safety Information and Indication

IMPORTANT SAFETY INFORMATION

Do not receive ENJAYMO if you are allergic to sutimlimab-jome or any of the ingredients in ENJAYMO.

ENJAYMO can cause serious side effects, including:

• Serious Infections: ENJAYMO is a prescription medicine that affects your immune system. ENJAYMO can lower the ability of your immune system to fight infections. People who take ENJAYMO may have an increased risk of getting infections caused by certain kinds of bacteria such as Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. These infections may be serious or life-threatening. Some infections may quickly become life-threatening or cause death if not recognized and treated early.
  • You need to receive vaccinations against infections caused by certain kinds of bacteria at least 2 weeks before your first dose of ENJAYMO. You may need to have additional vaccinations during treatment.
  • If your healthcare provider decides that urgent treatment with ENJAYMO is needed, you should receive vaccinations as soon as possible.
  • Vaccinations may reduce the risk of these infections, but do not prevent all infections. Call your healthcare provider or get medical help right away if you get any new signs and symptoms of an infection, including:
    • fever
    • severe headache with stiff neck or back
    • pain during urination or urinating more often than usual
    • cough or difficulty breathing
    • flu-like symptoms
    • pain, redness, or swelling of the skin
• Infusion-related reactions: Treatment with ENJAYMO may cause infusion-related reactions, including allergic reactions that may be serious or life-threatening. Your healthcare provider may slow down or stop your ENJAYMO infusion if you have an infusion-related reaction and will treat your symptoms if needed. Tell your healthcare provider right away if you develop symptoms during your ENJAYMO infusion that may mean you are having an infusion-related reaction, including:
  • shortness of breath
  • decrease in blood pressure
  • chest discomfort
  • rapid heartbeat
  • nausea
  • injection site reaction
  • flushing
  • headache
  • dizziness
  • rash
  • itchy skin
• Risk of autoimmune disease: ENJAYMO may increase your risk for developing an autoimmune disease such as systemic lupus erythematosus (SLE). Tell your healthcare provider and get medical help if you develop any symptoms of SLE, including:
  • joint pain or swelling
  • rash on the cheeks and nose
  • unexplained fever
• If you have CAD and you stop receiving ENJAYMO, your healthcare provider should monitor you closely for the return of your symptoms after you stop ENJAYMO. Stopping ENJAYMO may cause the breakdown of your red blood cells due to CAD return. Symptoms or problems that can happen due to red blood cell breakdown include:
  • tiredness
  • shortness of breath
  • rapid heart rate
  • blood in your urine or dark urine

The most common side effects of ENJAYMO include:

• increase in blood pressure
• urinary tract infection
• respiratory tract infection
• bacterial infection
• swelling in lower legs or hands
• joint pain
• headache
• nausea
• runny nose
• bluish color to the lips and skin
• dizziness
• feeling tired or weak
• cough
• changes in color or sensation in the fingers and toes (Raynaud’s phenomenon)

These are not all the possible side effects of ENJAYMO. Call your doctor for medical advice about side effects.

Before receiving ENJAYMO, tell your healthcare provider about all of your medical conditions, including if you:

• have a fever or infection, including a history of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C.
• have an autoimmune disease such as systemic lupus erythematosus (SLE), also known as lupus.
• are pregnant or plan to become pregnant. It is not known if ENJAYMO will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if ENJAYMO passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

INDICATION

ENJAYMO® is a prescription medicine used to treat the breakdown of red blood cells (hemolysis) in adults with cold agglutinin disease (CAD).

It is not known if ENJAYMO is safe and effective in children.

Please see Full Prescribing Information, including Medication Guide.

References

1. Farid Y, Bowman NS, Lecat P. Biochemistry, Hemoglobin Synthesis. StatPearls. 2022.
2. Collie JC. Cold agglutinin disease. Practice Essentials, Pathophysiology, Etiology. Medscape. Updated February 7, 2022. https://emedicine.medscape.com/article/135327-overview.
3. Joly F, Schmitt LA, Watson PAM, et al. JMIR Form Res. 2022;6(7):e34248.
4. Röth A, Berentsen S, Barcellini W, et al. Blood. 2022;140(9):980-991.
5. Enjamyo (sutimlimab-jome) [package insert]. Sanofi; 2023.

MAT-US-2303524-v1.0-05/2023

© 2023 Genzyme Corporation. All rights reserved.

ENJAYMO and Sanofi are registered trademarks of Sanofi or an affiliate.

2023-06-13T07:01:00

(BPT) – Sponsored by Lilly USA, LLC

Having a support system of family and friends is an important part of anyone’s life, but especially for someone living with psoriasis. Many turn to their partners as someone to lean on throughout their diagnosis and treatment journey.

Psoriasis, a common chronic autoimmune disease that affects the skin, impacts more than 125 million people globally. The most common form of psoriasis, plaque psoriasis, presents as red and inflamed patches covered by white scales.

Eddie, a born-and-raised New Yorker, is one of many people impacted by moderate to severe plaque psoriasis, and he understands the impact his disease has on his partner, Nick. For someone who doesn’t have this condition, it can be difficult to understand. “Nick heard me talk about how the plaques looked and felt, but he could never really know what it was like to go through what I was going through.”

According to the National Psoriasis Foundation, having a chronic disease such as psoriasis can make it challenging for both care partners and the person who has the disease. It may be difficult to talk to your partner, friends and family about your psoriasis and how it affects your life, but the organization recommends not avoiding these conversations.

Much like others with moderate to severe plaque psoriasis, Eddie has a long history of physical symptoms. His partner, Nick, recounts days when Eddie’s plaques were flaky, which made Eddie feel embarrassed enough to want to cover his skin.

After trying many over the counter creams and steroids, Eddie found a dermatologist who recommended Taltz^® (ixekizumab) injection 80 mg/mL, which resulted in rapid relief from his bothersome symptoms and total clearance of the plaques on his skin.* Thanks to Taltz, Eddie’s skin is clearer and he’s focusing on what matters most to him: friends, family and Nick.

Taltz is a prescription medicine approved for adults and children six years and older with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light). Taltz affects the immune system. It may increase your risk of infections, which can be serious. Do not use Taltz if you have any symptoms of infection, unless your doctor tells you to. If you have a symptom after starting Taltz, call your doctor right away. Learn more about patients like Eddie and their experiences with Taltz.

*This article represents Eddie’s personal experiences. While Eddie saw complete clearance with Taltz, individual results may vary. In clinical trials, at 12 weeks, up to 90 percent of people saw a significant improvement of their psoriasis plaques, and four out of ten people achieved completely clear skin.

Helpful Tips for Caretakers from Eddie and Nick’s Perspective

From the perspective of a partner and caretaker, here are some helpful tips to consider when caring for someone with moderate to severe plaque psoriasis:

• DO have an understanding of the disease

Having a strong understanding of your partner’s condition is invaluable to support your loved one. For helpful resources and to learn more about psoriasis, visit The National Psoriasis Foundation and Taltz.com.

• DON’T push too hard for information or give unwanted advice

It’s important to respect your partner’s feelings and decisions regarding their disease journey. Eddie shares, “Until you deal with it, you don’t know what it’s like.” Be sure to honor boundaries and keep your distance when asked.

• DO listen to what they are telling you

As a caretaker, Nick notes, “It’s important to understand why your loved one is feeling the way they are and to comfort them as much as you can, even knowing that there’s nothing you can do physically to remedy the disease.” However, listening entails more than hearing their words. It also involves picking up on their behavioral changes and paying attention to their actions so you can best support them.

• DO check in to see if you are giving the support they need

Being a caretaker doesn’t come with a roadmap. Communicate with your partner to ensure you are providing the type of support they want and need.

• DON’T forget to take care of yourself

Taking care of your own mental and physical wellbeing is just as important as caring for your partner. Prioritizing your own needs allows you to be in the best position to support your partner through the experience of living with plaque psoriasis.

Ask your doctor about treatment options, like Taltz, if you are living with moderate to severe plaque psoriasis

Eddie recommends talking to your doctor about available treatment options, including Taltz, if you are living with this condition and hoping for complete skin clearance.

If you have moderate to severe plaque psoriasis, talk to your doctor about Taltz to see if it could be the right treatment for you.

Eddie and Nick were compensated for their time to provide insights on this topic.

INDICATIONS AND SAFETY SUMMARY

Taltz^® (tol-ts) is an injectable medicine used to treat:

• People 6 years of age and older with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
• Adults with active psoriatic arthritis.
• Adults with active ankylosing spondylitis.
• Adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation.

It is not known if Taltz is safe and effective in children for conditions other than plaque psoriasis or in children under 6 years of age.

Warnings – Taltz affects the immune system. It may increase your risk of infections, which can be serious. Do not use Taltz if you have any symptoms of infection, unless your doctor tells you to. If you have a symptom after starting Taltz, call your doctor right away.

Your doctor should check you for tuberculosis (TB) before you start Taltz, and watch you closely for signs of TB during and after treatment with Taltz. If you have TB, or had it in the past, your doctor may treat you for it before you start Taltz.

Do not use Taltz if you have had a serious allergic reaction to ixekizumab or any other ingredient in Taltz, such as: swelling of your eyelids, lips, mouth, tongue or throat, trouble breathing, feeling faint, throat or chest tightness, or skin rash. Get emergency help right away if you have any of these reactions. See the Medication Guide that comes with Taltz for a list of ingredients.

Crohn’s disease or ulcerative colitis (inflammatory bowel disease) can start or get worse with Taltz use. Tell your doctor if you have any of these symptoms or if they get worse: stomach pain, diarrhea, and weight loss.

You should not get live vaccines while taking Taltz. You should get the vaccines you need before you start Taltz.

Common side effects

The most common side effects of Taltz include:

Injection site reactions	Upper respiratory infections
Nausea	Fungal skin infections

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Taltz, review these questions with your doctor:

• Are you being treated for an infection?
• Do you have an infection that does not go away or keeps coming back?
• Do you have TB or have you been in close contact with someone with TB?
• Do you have possible symptoms of an infection such as fever, cough, sores, diarrhea, or
  other symptoms? Ask your doctor about other possible symptoms.
• Do you have Crohn’s disease or ulcerative colitis?

Tell your doctor if:

• You need any vaccines or have had one recently.
• You take prescription or over-the-counter medicines, vitamins, or herbal supplements.
• You are pregnant or planning to become pregnant. It is not known if Taltz can harm an unborn baby. Pregnancy Exposure Registry: There is a pregnancy registry to collect information about women who are exposed to Taltz during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. If you become pregnant while taking Taltz, you are encouraged to enroll in the pregnancy registry by calling 1-800-284-1695 or by visiting online at https://www.taltz.com.
• You are breastfeeding or planning to breastfeed. It is not known if Taltz passes into breastmilk.

How to take

See the instructions for use that come with Taltz. There you will find information about how to store, prepare, and inject Taltz. Adults may self-inject after receiving training from a healthcare provider.

For people under 18 years of age:

• Weighing less than 50 kg (i.e., 110 lb): Taltz must be given by a healthcare provider.
• Weighing more than 50 kg (i.e., 110 lb): If your healthcare provider decides that your caregiver may give your injections of Taltz at home, your caregiver should ask and receive training from a healthcare provider on the right way to prepare and inject Taltz.

Learn more

Taltz is a prescription medicine. For more information, call 1-800-545-5979 or go to taltz.com.

This summary provides basic information about Taltz but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Taltz and how to take it. Your doctor is the best person to help you decide if Taltz is right for you.

IX CON BS 05OCT2022

Taltz^® and its delivery device base are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

PP-IX-US-6265 05/2023 ©Lilly USA, LLC 2023. All rights reserved.

2023-06-09T17:39:00

(BPT) – July 1 is Flush Smart Day, a nationwide initiative to educate and encourage everyone to practice smart flushing habits all year long. All too often, products that weren’t designed to be flushed down the toilet end up in pipes and sewer systems, causing damage to a home’s sewer system and beyond.

According to the Association of Nonwoven Fabrics Industry (INDA), more than 90% of wipes sold are not designed to be flushed. That’s because non-flushable wipes are made from long synthetic fibers, making them durable for their intended purpose. However, these durable fibers also make these items a danger to your plumbing.

This Flush Smart Day, the Responsible Flushing Alliance wants to help you learn how to flush smart today and beyond. Here are some simple tips to help avoid costly plumbing issues at home and protect the environment by reducing sewer blockages.

1. Know what you can’t flush

Your toilet is not a trashcan. Just because something is small enough to pass through the toilet pipe doesn’t mean it should be flushed. Non-flushable items can cause a lot of damage to homes, schools, businesses, sewers, wastewater treatment facilities, and the environment when flushed. Here’s a list of some commonly flushed items that should never be flushed:

• Baby wipes
• Period products
• Hard surface or cleaning wipes
• Makeup removing wipes
• Cotton balls, pads or swabs
• Sheet masks
• Dental floss, teeth whitening strips, contact lenses
• Hair or hair weaves
• Paper towels or rags
• Trash, cat litter
• Medicine, syringes

2. Educate family and houseguests

If you don’t know what you can’t flush, chances are your household and guests won’t either. Help them (and yourself) out by posting a sign on or near the toilet with a list of non-flushable items as a reminder.

Make sure there’s a small trash can next to the toilet to make it easy to dispose of non-flushable items. You can also keep disposable bags near the trashcan to wrap up diapers, baby wipes, and period products.

3. Properly dispose of FOGs

Fats, oils and greases (FOGs) can cause just as much damage as solid non-flushable items. Don’t flush FOGs down the toilet or pour them down the sink. Otherwise, you may be helping create a fatberg. When FOGs and non-flushable items collect in pipes, they can create a large, rock-like mass of waste matter in the sewer system. These fatbergs can grow and eventually destroy pipes and homes if left unchecked. You can find instructions on how to make your own FOG can at FlushSmart.org.

4. Look for the “Do Not Flush” symbol

Sometimes, it can be difficult to determine if an item, like wipes, can be flushed. You can double-check if an item is not flushable by looking for the “Do Not Flush” symbol on the packaging. If you see the symbol on the wipes packaging, do not flush the wipes down the toilet!

5. When in doubt, throw it out!

If you’re not 100% sure an item can be flushed, err on the side of caution. Throw it out and don’t risk your plumbing, home, and the environment by flushing something that isn’t meant to be flushed.

This July and beyond, flush smart and avoid costly clogs and other consequences. By doing your part and flushing responsibly, you can help protect your home plumbing, local sewers, water treatment plants, and environment. For more tips, information, and resources, visit FlushSmart.org and follow @FlushSmart on Twitter and Facebook.

2023-06-07T05:01:01

(BPT) – In honor of World Caring Day, a global celebration of compassion and support, we delve into the vital role of caregivers and the significance of self-care in their lives.

Whether you’re a parent, spouse, sibling, grandparent or other relative or friend caring for a loved one, you play a vital role in their well-being. Caring Bridge — a nonprofit that provides no-cost dedicated, private, ad-free space for communication, support and connection for a loved one’s health journey — is bringing awareness to the role of family caregivers and how they can care for themselves. Read on to learn about the three signs that you may be in a caring role and tips on nurturing yourself today and beyond.

Do you care for a loved one?

Often, family carers don’t realize they’re in a caregiving situation. For example, a husband may temporarily take care of his wife, who’s broken her leg and help with activities and tasks she can’t do independently because of her injury. Or perhaps an adult child finds that their mother increasingly relies on them for care after a dementia diagnosis.

Whether a medical condition is temporary or permanent, many family members become care participants in their loved ones’ lives without knowing it or meaning to. Here are three signs that you may have transitioned into a care role.

• You have increased responsibilities for the well-being and care of a loved one. This may include providing emotional support, managing medical appointments, assisting with daily activities or coordinating care services.
• You’ve had lifestyle adjustments, such as changes in routines, living arrangements or career choices, to care for your loved one.
• Your relationship with the person who receives your care and others in your life has changed. You may feel stronger bonds with the person you care about and experience strain or tension in your relationships because of your responsibilities.

Not all of these signs may apply to everyone. Family care participants have a variety of experiences. Whether they identify as a caregiver, carer, care participant, care partner or avoid labels altogether, they provide invaluable support to their loved ones.

However, to care for others, it’s critical that you also care for yourself. Your well-being should also be as much of a priority as that of your loved one. Here are five ways you can care for yourself while participating in care for others.

1. Practice stress management

The extra responsibilities of being a care partner can be stressful, especially if you have no or minimal help and support. It’s important to take breaks from caring and focus on your needs.

Consider engaging in activities that can help reduce stress to maintain your well-being. Some healthy ways to manage stress include deep breathing exercises, meditation, yoga, walking, running, spending time with friends or any activity you enjoy.

2. Care for yourself

You work hard, and it’s important to remember that you deserve care too. Set time aside every day to take care of you! Take a walk, read a book, watch a movie, paint or write. Anything that makes you feel happy and relaxed is worth doing so you can prioritize yourself while still helping others.

If your financial situation allows, enjoy a spa day, get a manicure and pedicure or book a massage. These forms of self-care can get you out of the house and allow you space and time to focus on nourishing yourself.

Don’t wait until you feel burnt out to enjoy some self-care. If your schedule and budget allow, set regular weekly or monthly appointments that you can look forward to and know that you can also receive care.

3. Prioritize your health

It’s easy for carers to ignore their health when they’re busy helping others with daily tasks. However, you can’t neglect your health. Just like airplane safety videos remind you, it’s important to put on your own oxygen mask before assisting others.

Take stock of your health. If it’s been a while since you’ve had a preventative care visit or need another medical appointment, it’s a good idea to book now so you can work it into your schedule. You can also care for your physical and mental health by eating a balanced diet, exercising, journaling and sleeping well.

4. Maintain relationships

Many people who care for their loved ones say they feel overwhelmed, isolated and lonely as they support their family member’s health journey. These feelings aren’t just emotional burdens.

According to findings by the U.S. Surgeon General, prolonged loneliness is akin to smoking up to 15 cigarettes a day. Also, poor social relationships, social isolation and loneliness can increase your risk of heart disease by 29% and stroke by 32%.

To improve your stress response and minimize the negative health effects of stress, it’s important that you stay socially connected. Schedule regular get-togethers with friends, pursue hobbies or interests with others and reach out for help when needed.

5. Find community

Not everyone understands what you’re going through in your specific caring situations. Still, many people provide care to family members just like you. You can feel less alone, ask for advice and find community with other family caregivers through support groups.

One way you can share your experiences, build connections, find comfort and receive valuable insight from others who understand is by visiting CaringBridge.com. Here, you’ll find resources and a community that can help you feel less alone and overwhelmed in your role as a carer.

You can also create a CaringBridge site to easily communicate health updates to a group of loved ones. The nonprofit solution is no cost, easy to use and designed to share your family member’s health journeys all on a private communication platform with no ads. To learn more or make a donation, visit CaringBridge.org.

2023-06-07T05:01:01

(BPT) – Stretch marks — you know them as those annoying long, narrow streaks, stripes or lines that can develop on your skin. They tend to pop up when your skin becomes stretched out or starts to sag, especially during periods of rapid growth, weight gain or loss, or pregnancy.

Anyone can develop stretch marks, but they are most common in women. They can show up on your stomach, thighs, hips, breasts, upper arms and lower back. Additionally, genetics play a role in determining who is more prone to developing stretch marks, meaning you might have your parents to thank for this unique feature.

Unfortunately, until now the most common ways to improve stretch marks have been to apply Vitamin E, cocoa butter and skincare products with glycolic acid, but it can take a long time to see any significant improvement with these topical products. Recent advancements in technology have brought about a new solution for reducing the appearance of stretch marks, especially the hottest trend right now, microneedling. But how can you boost an already great treatment? Enter Secret^® PRO from Cutera^®, the secret weapon for reducing the appearance of stretch marks and signs of aging.*

Secret PRO takes a unique approach to skin revitalization by combining two powerful technologies — fractional CO₂ laser and radiofrequency microneedling. These two modalities work safely and effectively to treat the deepest layers of your skin where stretch marks turn up. While the CO₂ laser targets the outermost layers of the skin, Secret PRO’s effective RF energy can reach down to the deeper layers of your skin to stimulate collagen remodeling and brighten and smooth the skin for a revitalized appearance overall.*

According to Facial Plastic Surgeon Prem Tripathi, MD, MPH of Silhouette Aesthetics in Livermore, CA, “The Secret PRO delivers amazing results. We can customize a treatment program for each individual patient to achieve the best possible results for a wide range of skin concerns. One of the areas where this innovative dual technology is very effective is for patients who are concerned about stretch marks.”

“This treatment utilizes microneedles to deliver RF energy into varying skin levels, allowing us to tailor treatments to each patient’s concerns. For example, radiofrequency with the Secret PRO is an ideal treatment for any area you are bothered by from aging, weight gain and loss, as well as childbirth. We can reduce the effects of sun damage, improve skin texture and tone, and promote collagen production to reduce the appearance of stretch marks, scars, and fine lines and wrinkles with fractional skin resurfacing,” says Dr. Tripathi.*

Dr. Tammy Chen of Central Park Laser Aesthetics in New York City uses the Secret PRO to address her patients’ face, neck, chest, as well as surgical scars and stretch marks for men and women.* “The results we can achieve are incredible. I call it a non-surgical lift without the downtime associated with more invasive options. There is minimal swelling and downtime for most of our patients so they can get back to their busy lives very quickly.”

“Since Secret PRO treatments are non-invasive, there is no need to undergo anesthesia. We use a topical anesthetic to keep patients comfortable and the treatment typically takes about 30-40 minutes. They just lay back, relax and watch TV or chat with me while I do the treatment. The procedure is well tolerated, and patients are excited to come back for more treatments.”^†

“It is very safe and the results we can achieve are more natural looking than many other invasive treatments. Patients can achieve the visible results they are looking for with little to no downtime. We can use the Secret PRO safely for all skin types, from very fair to light brown skin that tans easily,” says Dr. Chen.‡

Want to find out if you are a candidate for Secret PRO? Find a Secret PRO practice near you.

*By way of resurfacing and hemostasis and coagulation.

†Patient results may vary.

‡CO₂ can only be used for Fitzpatrick Skin Types 1-4.

2023-06-02T07:01:00

(BPT) – Are you or a loved one a post-9/11 combat veteran? Were you exposed to burn pits or other toxins while in service? If so, there’s important information you should know regarding your veterans’ health care and disability benefits, including two fast-approaching deadlines.

Veterans who were exposed to burn pits or other toxic substances may experience various health issues. Veterans who think their diagnosed medical conditions are connected to toxic exposure during service should file a claim with the Department of Veterans Affairs (VA).

Veterans not currently experiencing any health problems may have some in the future. Even if they feel fine, eligible veterans should get a toxic exposure screening. Toxic exposure screenings are available at VA health facilities across the country.

Thankfully, new legislation called the PACT Act will help veterans get the treatment and benefits they deserve.

Army veteran Andrew Myatt, who deployed to Iraq in 2004-05, said, “On paper, I did everything I was supposed to. I don’t drink soda or eat fast food. I have a very healthy lifestyle and diet. And yet, I’ve come down with two cancers in the last three years.”

What is the PACT Act?

The Sergeant First Class Heath Robinson Honoring Our PACT Act became law on Aug. 10, 2022. This bill addresses one of the most urgent issues for post-9/11 veterans — health problems related to exposure to burn pits and other toxic substances.

The PACT Act grants permanent VA health care eligibility to 3.5 million post-9/11 veterans who may have been exposed to toxic substances during service. The Act adds more than 20 new presumptive service-connected illnesses related to exposure to burn pits and other toxic substances for veterans who served in Iraq, Afghanistan, and surrounding areas.

Veterans nonprofit Wounded Warrior Project strongly advocated for this bill and is working hard to spread the word about expanded access to health care and disability benefits for impacted veterans.

Act now to maximize benefits

Time is running out for exposed veterans to maximize these benefits. Veterans must file a claim with the VA by Aug. 9, 2023, to be eligible for retroactive disability compensation dated back to Aug. 10, 2022 (when the bill was signed into law), if they were diagnosed with a qualifying condition at that time.

Post-9/11 combat veterans discharged over 10 years ago and not enrolled in VA health care have a deadline of Oct. 1, 2023, to take advantage of the open enrollment period. If they miss it, they could be subject to a phased-in enrollment period, based on their discharge from service.

Get started today at VA.gov/PACT.

“Even if they aren’t sick now, I would urge all post-9/11 veterans to register for VA health care,” said WWP CEO Lt. Gen. (Ret.) Mike Linnington. “For combat veterans exposed to burn pits and other toxic substances while serving our nation, the PACT Act helps alleviate the burden of proof needed to make a service connection for VA benefits. Veterans who qualify under the PACT Act and are diagnosed with cancer have priority when it comes to VA health care and other benefits.”

Veterans are strongly advised to work with an accredited VA representative to advocate for their needs. One option is Wounded Warrior Project, which has accredited representatives that work with the VA to advocate for veterans.

2023-06-01T09:41:00

(BPT) – If one of your goals is to take better care of your health, you likely take vitamins every day — or at least a multivitamin pill — to ensure that your body is getting the nutrients it needs. Ideally, people should get enough of their essential nutrition from food, but when you’re busy, it’s all too easy to skip meals or grab convenience food, so you don’t get a balanced diet throughout the day.

Whether you’re taking capsules, pills or soft gels to help supplement the vital nutrients you take in each day, chances are some may be large or tough to swallow — or all too easy to forget about taking each day. But did you know that beyond being easier to swallow, multivitamin powders can also provide other health benefits?

What is a multivitamin powder?

As the name suggests, a multivitamin powder is essentially a multivitamin in powder form. Multivitamin powders offer the perfect solution for anyone who finds pills difficult to take, or for those who are tired of taking multiple supplements to try to provide their body the nutrients it needs.

If you’re looking for a well-rounded multivitamin powder, CardioFitMD^® Cardiovascular and Whole Body Health delivers 29% of the recommended daily serving of fiber — which about 95% of Americans don’t get enough of — plus powerful probiotics, prebiotics and a potent dose of beetroot powder to support your healthy digestive and heart function. It also contains 20 essential vitamins and minerals to promote whole-body health and proper energy for an active lifestyle, including 100% (or more) of the Recommended Dietary Intake of the most prevalent vitamin and mineral deficiencies facing Americans today: vitamin A, vitamin C, vitamin D3, vitamin E, vitamin K, thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, selenium and manganese.

Here’s the scoop on why a multivitamin powder may be just what you need to enhance your well-being.

1. Better taste

Pills and capsules don’t usually have any taste, but most multivitamin powders come in a variety of flavors, so you can get your daily nutrients and give your water a flavorful boost at the same time. If it tastes good, you’re more likely to be consistent in taking it — so your multivitamins quickly become a tasty part of each day.

2. Encourages more hydration

Because you’ll be mixing your vitamin powder with water or another liquid, you will also be drinking more every day, which is important for optimal health.

3. Easier to take

Taking capsules or pills every day can be inconvenient or unpleasant for many who just don’t like taking pills. A powder-based multivitamin is a convenient way to ensure that you’re getting your vital nutrients each morning. A flavored powder can be mixed into your morning juice, smoothie or water. You can even take it along in your favorite water bottle on-the-go for busy mornings.

4. Powders are more potent

Pills and capsules need to be small for easy swallowing, but there’s only so much you can cram into a small pill. In addition, a number of fillers are required to form a pill, which makes it more difficult to provide a higher level of nutrients in this form. Depending on your individual needs, a vitamin powder mix may actually contain a greater amount of vitamins and minerals than the average pill.

5. Quicker absorption

Capsules and pills are not designed to achieve instant results — they need to work their way through your gut for absorption before the nutrients can get to work. On the other hand, drinking your nutrients allows them to absorb more quickly, so they get to work in your body sooner.

Comprehensive, convenient nutrition

With all of the essential daily nutrients of CardioFitMD^® in one scoop, taking control of your health has never been easier. It’s a great-tasting, nutrient-rich drink with a broad-spectrum insoluble and soluble fiber and prebiotic blend, Bacillus coagulans probiotic, beetroot powder and essential vitamins and minerals that promote circulatory, digestive, immune and heart health to help you maintain a healthy, active lifestyle as you age.

For more information about multivitamin powders, visit 1MD.org.

2023-06-01T04:01:00

(BPT) – Cancer is the second-leading cause of death for men in the United States. While the cause of most cancers is unknown, about one in 10 cancers are caused by changes in genes that can be passed down in families. In recognition of Men’s Health Month, here are seven things every man should know about hereditary cancer and genetic testing.

1. Mutations in dozens of different genes can increase your odds of getting cancer.

News stories about celebrities like Angelina Jolie have made people aware that mutations in the BRCA genes can cause breast and ovarian cancer, but that’s not the whole story. There are dozens of genes with mutations linked to a variety of cancers — including colorectal, pancreatic, prostate and skin cancer — that can affect people regardless of their gender. Genetic testing on blood or saliva can help people learn if they are at high risk for these cancers.

2. Up to 90% of people are unaware they have a genetic mutation that increases their cancer risk. Men are less likely than women to know about or undergo genetic testing.

Most people have no idea they are predisposed to cancer until they — or a close family member — receive a cancer diagnosis that leads to genetic testing. Men are less likely than women to be told about or offered cancer genetic testing.

3. Inherited BRCA mutations pose serious cancer risks to men.

Men who test positive for a BRCA1 or BRCA2 mutation have an increased risk for a variety of cancers. Men with mutations in their BRCA2 gene have a 20 to 60% lifetime risk for prostate cancer, compared to 13% for the general population. These men are also more likely to develop an aggressive form of prostate cancer at a younger age. BRCA2 mutations raise the lifetime risk of male breast cancer from 0.1% to as high as 5-10%. Regardless of gender, BRCA2 mutations increase the lifetime risk of getting pancreatic cancer from 1.5% to as much as 10%. BRCA1 mutations also increase the risk for male breast cancer, pancreatic and prostate cancer, although these risks are lower than in people with a BRCA2 mutation.

4. Other genetic mutations can put people at high risk for colorectal cancer.

The lifetime risk of developing colorectal cancer is up to 52% for people with a gene mutation associated with a lesser-known condition called Lynch syndrome, compared to about 4% for the general population. These people also tend to get cancer at an earlier-than-average age. It’s estimated that over 1 million people have Lynch syndrome in the United States, yet less than 10% are aware of their status.

5. Men and women can pass cancer-causing genetic mutations on to their children.

A man with an inherited mutation linked to cancer has a 50% chance of passing it on to each of his children. Children inherit their genes from both parents, and men are just as likely as women to inherit or pass on mutations linked to cancer.

6. Being aware of your cancer risk can save your life.

Some people shrug off the idea of genetic testing because they believe there’s nothing that they can do to prevent cancer — but that thinking is flawed. Men who know they’re at high risk can schedule more frequent cancer screenings, which increases the odds of catching cancer early, before it spreads. Fathers who know their genetic status can also protect the health of their children, who may have inherited the same mutation.

7. Support is out there.

FORCE (Facing Our Risk of Cancer Empowered) is dedicated to providing up-to-date, expert-reviewed information and resources that help people make informed medical decisions regarding hereditary cancer. The organization also offers a peer support network, up-to-date medical information and support groups specifically for men.

2023-05-31T13:01:00

(BPT) – The story you are about to read is that of Ben, a person living with bipolar 1. The experiences and opinions expressed here may not be representative of all people living with bipolar 1 and are not a substitute for medical advice or judgment. Always talk to your healthcare provider about available and appropriate treatment options. Individual results may vary.

Staying in all day and going out all night. Spending money and drinking to excess. Episodes of frustration and anger that didn’t make sense. I didn’t know it at the time, but my behaviors were associated with some of the changes in mood and energy that are symptoms of bipolar I disorder.¹ It took finding the right healthcare provider, who diagnosed me, to begin my journey towards finding a treatment option that works for me.

My mental health journey started in my late teen years when I would cycle through feelings of being “low,” also known as depressive symptoms, and then I would experience “highs,” or manic symptoms. My manic episodes could be really frightening — I’d become irrationally and extremely angry, sometimes falling into a blind rage and lashing out.

I knew that what I was experiencing and how I was feeling weren’t normal. I was hospitalized multiple times and I wanted answers and help.

When I was 19, I started seeing a new healthcare provider and I found in him someone I thought would be a good partner. He was young and approachable, and I knew he really wanted to help me reach my treatment goals. Ultimately, my healthcare provider diagnosed me with bipolar 1 and while it was difficult to hear, having the diagnosis was a big relief because then we could work together on a treatment plan.

From the outset, I trusted and felt supported by my healthcare provider. He always listened to my concerns, which were typical of anyone starting a treatment journey. We worked together to consider different medications and he took the time to explain how each one worked, as well as the potential benefits and side effects and how I might feel when taking the medication.

Following my diagnosis, I began treatment with medication, but it was hard to find one that worked for me. One medicine helped reduce my bipolar 1 symptoms; but, unfortunately, it came with side effects I couldn’t tolerate. I tried several other medications, but for me, they didn’t help to manage my condition and my symptoms as much as I wanted them to, so I stopped taking them and my symptoms returned. My wife, who has been by my side every step of the way before and after my diagnosis, could tell when I stopped taking medication. When my symptoms weren’t managed, I’d become more easily frustrated and agitated, which would make her worry.

Then my healthcare provider told me about LYBALVI^® (olanzapine and samidorphan) and together we decided I should try it. In 2021, LYBALVI was approved as an oral medication used in adults to treat manic or mixed episodes that happen with bipolar 1 disorder, either alone for short-term (acute) or maintenance treatment or in conjunction with valproate or lithium.²

My healthcare provider shared with me some important safety information about LYBALVI, including that LYBALVI has a boxed warning. More specifically, LYBALVI may cause serious side effects, including increased risk of death in elderly people with dementia-related psychosis. LYBALVI increases the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). LYBALVI is not approved for the treatment of people with dementia-related psychosis.²

Since starting LYBALVI, I have noticed improvement in my bipolar 1 symptoms, which my wife and family have also noticed. I take LYBALVI every day as prescribed because I see that it works for me and the side effects have been manageable. However, this is just my experience, so it is important to talk with your healthcare provider about what may work for you.

My bipolar 1 journey hasn’t been easy and I still have good and bad days, but I try to focus on the people who support me and things in my life that are fulfilling to me. I enjoy spending time with my family and helping them with their restaurant. I’m also focused on developing my skills in my career as a software engineer. When I’m not working, I like going to the gym for exercise and when I want to relax and unplug, I enjoy playing video games.

With the support of my loved ones and a strong relationship with my healthcare provider, I feel hopeful about my path forward.

I believe mental health is just as important as physical health and should be taken as seriously. Unfortunately, the stigma around mental illness persists and can prevent people from getting the help they need. By sharing my story, I hope to do my part to help raise awareness and encourage others to get the help they may need.

For anyone experiencing symptoms of mental illness, including bipolar 1, I encourage you to reach out for help. Be your own best advocate, or advocate for a loved one. Talk with a medical professional about concerns and symptoms, ask questions and be honest – so they can help determine the treatment option that may work for you.

To learn more about LYBALVI, visit www.LYBALVI.com and talk with your doctor.

INDICATIONS AND IMPORTANT SAFETY INFORMATION

Important Safety Information

LYBALVI may cause serious side effects, including increased risk of death in elderly people with dementia-related psychosis. LYBALVI increases the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). LYBALVI is not approved for the treatment of people with dementia-related psychosis.

Do not take LYBALVI if you are taking opioids or are experiencing acute opioid withdrawal.

LYBALVI may cause serious side effects, including:

• Stroke (cerebrovascular problems) in elderly people with dementia-related psychosis that can lead to death.
• Opioid withdrawal. Do not take LYBALVI for at least 7 days after you stopped taking short-acting opioids and for at least 14 days after you stopped taking long-acting opioids. One of the medicines in LYBALVI (samidorphan) can cause opioid withdrawal that may be severe and cause hospitalization in people who are physically dependent on opioids. Talk to your healthcare provider if you have questions about the type of opioid you take.
• Risk of life-threatening opioid overdose. You should not start taking opioids for at least 5 days after you stop treatment with LYBALVI. One of the medicines in LYBALVI (samidorphan) can increase your chance of having an opioid overdose that can cause death if you take opioids during treatment or within 5 days after stopping treatment with LYBALVI.

  You can accidentally overdose in 2 ways:

  • LYBALVI blocks the effects of opioids, such as heroin, methadone, or opioid pain medicines. Do not take large amounts of opioids to try to overcome the opioid-blocking effects of LYBALVI. This can lead to serious injury, coma, or death.
  • After you take LYBALVI, its blocking effect slowly decreases and completely goes away over time. You may be more sensitive to the effects of opioids. If you have used opioid street drugs or opioid-containing medicines in the past, using opioids in amounts that you used before treatment with LYBALVI can lead to overdose or death.

  It is important that you tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose.
  
  You or someone close to you should get emergency medical help right away if you:

  • have trouble breathing
  • become very drowsy with slowed breathing
  • have slow, shallow breathing (little chest movement with breathing)
  • feel faint, very dizzy, confused, or have unusual symptoms

  
  Tell your healthcare provider if you are taking LYBALVI before a medical procedure or surgery.

• Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death. Call your healthcare provider or go to the nearest hospital emergency room right away if you have some or all of the following signs and symptoms of NMS:
  • high fever
  • stiff muscles
  • confusion
  • sweating
  • changes in your breathing, pulse, heart rate, and blood pressure
• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): One of the medicines in LYBALVI (olanzapine) can cause DRESS which can cause death. Tell your healthcare provider right away if you develop any of the following symptoms of DRESS, including:
  • rash
  • swollen glands
  • liver problems
  • heart problems
  • fever
  • kidney problems
  • lung problems
• Problems with your metabolism such as:
  • high blood sugar (hyperglycemia) and diabetes. Increases in blood sugar can happen in some people who take LYBALVI. Extremely high blood sugar can lead to coma or death. Your healthcare provider should check your blood sugar before you start and regularly during treatment with LYBALVI.

    Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with LYBALVI:

    • feel very thirsty
    • feel very hungry
    • feel sick to your stomach
    • need to urinate more than usual
    • feel weak or tired
    • feel confused, or your breath smells fruity
  • increased fat levels (cholesterol and triglycerides) in your blood. Your healthcare provider should check the fat levels in your blood before you start and regularly during treatment with LYBALVI.
  • weight gain. You and your healthcare provider should check your weight before you start and often during treatment with LYBALVI.
• Uncontrolled body movements (tardive dyskinesia). LYBALVI may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop taking LYBALVI. Tardive dyskinesia may also start after you stop taking LYBALVI.
• Decreased blood pressure (orthostatic hypotension) and fainting. You may feel lightheaded or faint when you rise too quickly from a sitting or lying position.
• Falls. LYBALVI may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries.
• Low white blood cell count. Your healthcare provider may do blood tests during the first few months of treatment with LYBALVI.
• Difficulty swallowing that can cause food or liquid to get into your lungs.
• Seizures (convulsions).
• Problems controlling your body temperature so that you feel too warm.
• Increased prolactin levels in your blood. Your healthcare provider may do blood tests to check your prolactin levels during treatment with LYBALVI.

The most common side effects of LYBALVI when used to treat people with schizophrenia include:

• weight gain
• dry mouth
• sleepiness
• headache

The most common side effects of LYBALVI when used alone to treat people with mixed or manic episodes that happen with bipolar I disorder include:

• weakness
• constipation
• sleepiness
• shaking
• dry mouth
• increased appetite
• dizziness

The most common side effects of LYBALVI when used in combination with lithium or valproate to treat people with mixed or manic episodes that happen with bipolar I disorder include:

• dry mouth
• increased appetite
• back pain
• problems speaking
• memory problems
• weight gain
• dizziness
• constipation
• mouth watering
• numbness and tingling in your arm and legs

Do not drive a car, operate machinery, or do other dangerous activities until you know how LYBALVI affects you. LYBALVI may make you feel drowsy.

Avoid drinking alcohol during treatment with LYBALVI.

Avoid getting over-heated or dehydrated.

• • Do not exercise too much.
  • In hot weather, stay inside in a cool place if possible.
  • Stay out of the sun. Do not wear too much clothing or heavy clothing.
  • Drink plenty of water.

Before taking LYBALVI, tell your healthcare provider about all of your medical conditions, including if you:

• have or had heart problems or a stroke
• use or abuse street (illegal) drugs
• have or had low or high blood pressure
• have kidney problems
• have diabetes or high blood sugar or a family history of diabetes or high blood sugar
• have or have had high levels of total cholesterol, LDL cholesterol, or triglycerides or low levels of HDL cholesterol
• have or had a low white blood cell count
• have problems swallowing
• have or had seizures (convulsions)
• have or had problems with urination or prostate problems
• have or had breast cancer
• have or had constipation or a bowel obstruction
• have or had high prolactin levels
• are pregnant or plan to become pregnant. Talk to your healthcare provider about the risks to you and your unborn or newborn baby if you take LYBALVI during pregnancy.
  • Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with LYBALVI.
  • If you become pregnant during treatment with LYBALVI, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling 1-866-961-2388 or visit
    https://womensmentalhealth.org/clinical-and-research-programs/pregancyregistry/
• are breastfeeding or plan to breastfeed. LYBALVI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with LYBALVI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

LYBALVI and other medicines may affect each other causing possible serious side effects.

LYBALVI may affect the way other medicines work, and other medicines may affect how LYBALVI works.

Especially tell your healthcare provider if you:

• take opioids or have stopped taking opioids in the past 14 days
• take or plan to take other olanzapine containing medicines

Your healthcare provider can tell you if it is safe to take LYBALVI with your other medicines. Do not start or stop any medicines while taking LYBALVI without first talking to your healthcare provider.

These are not all the possible side effects of LYBALVI.

Call your healthcare provider for medical advice about side effects. You may report side effects to
FDA at 1-800-FDA-1088.

Indications

LYBALVI is a prescription medicine which contains 2 medicines (olanzapine and samidorphan) used in adults:

• to treat schizophrenia
• alone for short­ term (acute) or maintenance treatment of manic or mixed episodes that happen with bipolar I disorder
• in combination with valproate or lithium to treat manic or mixed episodes that happen with bipolar I disorder

It is not known if LYBALVI is safe or effective in children.

Please see full Prescribing Information, including Boxed Warning, and Medication Guide.

References

¹ American Psychiatric Association. What is Bipolar disorder? Accessed March 29, 2023. https://www.psychiatry.org/patients-families/bipolar-disorders/what-are-bipolar-disorders

² LYBALVI^® [Prescribing Information]. Alkermes, Inc. Waltham, MA:2021

ALKERMES^® is a registered trademark of Alkermes, Inc. LYBALVI^® and logo are registered trademarks of Alkermes Pharma Ireland Limited, used by Alkermes, Inc., under license. ©2023 Alkermes, Inc. All rights reserved. LYB-002472