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Five Ways to Love Your Heart During American Heart Month

2025-02-01T07:01:00

(BPT) – February is all about matters of the heart. Of course, there’s Valentine’s Day, a time to express affection for those we love, but it’s also American Heart Month, a time to raise awareness about the leading cause of death in the U.S. — heart disease. Understanding the risks, as well as steps for prevention, is especially important for older adults, as the risk of heart disease increases after age 65. Lifestyle improvements like regular exercise, a balanced diet, reduced stress, and a greater focus on health can have a significant impact, not only on heart disease but on general well-being. AARP members have access to tools and benefits that make it easy to give your heart some love.

“When you take care of your heart, you take care of your whole self,” said Doug Armstrong, Vice President, Health Products at AARP Services Inc. “AARP members have access to benefits that make it easy to prioritize your own health and overall well-being, from simplifying the process of finding a physician to discovering new ways to manage and save on medications.”

1. Reduce Stress

There are many things in life that can cause us to feel stressed — finances, work, family, and even health concerns. While it may be difficult to remove stressors in your life, one thing you can easily do is adjust how you react to them. Doing so can greatly benefit your heart. Research has shown that ongoing stress increases your heart rate and can narrow blood vessels, increasing your risk of heart attack.

Finding ways to relax and calm your nerves can lower your blood pressure. For some, it may be as simple as taking a walk or trying some deep breathing techniques. For others, apps or professional help might be more effective in reducing stress.

2. Know Your Risk

Age and lifestyle are known risk factors for heart disease, but family history is as well. The best way to identify your risk and develop a plan is with a physician. Additionally, it’s a good idea to consult your physician before beginning any exercise or fitness regimen.

If you have not yet established care with a primary care physician or are searching for a new one, Oak Street Health, the only primary care provider to carry the AARP name, provides primary care for adults on Medicare and focuses on prevention with personalized care to help keep you healthy — physically, mentally, and socially. Benefits include same-day/next-day appointments where available, convenient locations, a dedicated care team, and a 24/7 patient support line. AARP membership is not required to visit an Oak Street Health location.

3. Stay Active

Physical activity has so many benefits, especially as you get older. It can help build stronger bones, muscles and joints, boost your mental health, help you maintain a healthy weight, and reduce your risk of chronic diseases like heart disease. If you’re not regularly active, why not try something new this February? Sign up for a fitness class you’ve been considering or give pickleball a try. Join a walking group or download a fitness app. It’s recommended to get 30 minutes of aerobic exercise at least five times a week, which is great motivation to find some activities you enjoy. Oak Street Health offers a variety of events to help patients stay active and connected, like Zumba classes, line dancing lessons and game nights.

4. Stay on Track

Some people take medication to treat heart disease by lowering cholesterol or reducing high blood pressure. If your physician prescribes a treatment plan, it’s important to stay on track to ensure effectiveness.

But sometimes, high prescription prices make it difficult to adhere to a regimen. Luckily, AARP members have access to tools to help with savings, such as AARP® Prescription Discounts Provided by Optum RX®. This program offers a free prescription discount card that can be used at over 66,000 pharmacies nationwide for savings on FDA-approved medications. Additional benefits for AARP members include home delivery, deeper discounts on medications, coverage for dependents and more.

If your regimen requires multiple medications taken at specific times, it’s a good idea to get assistance with tracking them. Hero Smart Pill Dispenser stores, sorts and dispenses up to a 90-day supply of 10 different medications. The connected medication management app helps you manage medication routines, track your supply and understand your adherence. AARP members get exclusive savings on a Hero subscription.

5. Eat Well

A healthy, well-balanced diet is key to preventing heart disease. According to the American Heart Association, a diet rich in fruits and vegetables, whole grains, lean proteins, and minimally processed foods can be beneficial to your overall heart health. A healthy diet also reduces your risk of developing type 2 diabetes, high blood pressure, kidney disease and certain kinds of cancer. Plus, you might find that you have even more energy as you go about your day.

Simply put, heart-healthy habits are good lifestyle habits. So, this February, give your heart some love and be well. To learn more about AARP benefits that can help you achieve your heart health goals, visit aarp.org/benefits.

AARP and its affiliates are not insurers, agents, brokers or producers. AARP member benefits are provided by third parties, not by AARP or its affiliates. Providers pay a royalty fee to AARP for the use of its intellectual property. These fees are used for the general purposes of AARP. Some provider offers are subject to change and may have restrictions. Please contact the provider directly for details.

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Addressing hypoparathyroidism: New treatment now available

2025-01-31T14:31:00

(BPT) – For patients like Michele Rayes, life with hypoparathyroidism (hypopara) had been a constant uphill battle. Reflecting on her initial diagnosis, Rayes described it as a profound turning point in her life: “Little did I know, this was just the beginning of a tumultuous journey that would ultimately change the course — and the purpose — of my life forever.”

For years, managing this rare disease meant navigating a maze of challenges with limited treatment options. Now, there’s an FDA-approved treatment option available to the estimated 77,000 to 115,000 people in the United States affected by this rare disease.

Understanding hypoparathyroidism

Hypoparathyroidism is a rare endocrine disease caused by insufficient levels of parathyroid hormone (PTH). This deficiency disrupts the body’s calcium balance, leading to a range of severe and potentially life-threatening symptoms and health complications.

Most cases — around 75% — occur due to accidental damage to or removal of the parathyroid glands during neck surgery, such as a total thyroidectomy, while other causes stem from genetic conditions or associated medical disorders.

Until recently, hypoparathyroidism was one of the last hormone deficiency diseases in the United States without a treatment that directly targeted its underlying cause, leaving patients with limited options for managing their disease effectively.

The daily impact on patients’ lives

Living with hypoparathyroidism can be a daily struggle, impacting multiple aspects of physical and emotional well-being. Common challenges include chronic fatigue, muscle cramps and cognitive impairment often described as “brain fog”.

“When I was first diagnosed with this rare disease, nobody within my care team could explain it to me or prepare me for the crippling symptoms I was about to experience or the number of terrifying hospitalizations I would require because of those symptoms,” Rayes shared.

Hypoparathyroidism is also associated with a range of serious multi-organ complications, including kidney disease, cardiovascular issues and cognitive impairment. Conventional therapy, which consists of active vitamin D and calcium, may result in a high pill burden and does not address insufficient PTH.

Treatment now available

YORVIPATH® is the first and only FDA-approved treatment for hypoparathyroidism in adults in the United States. YORVIPATH is a prescription medicine used to treat adults with low parathyroid hormone (PTH). This ready-to-use, once-daily injection provides continuous exposure to active PTH throughout the 24-hour dosing period.

The safety and effectiveness of YORVIPATH have not been established in individuals recently diagnosed with hypoparathyroidism following surgery or those with low calcium levels at the start of treatment. Additionally, its use is not recommended in children or young adults with developing bones. YORVIPATH may lead to high or low calcium levels in the blood or possible bone cancer. For more detailed safety information, please refer to the end of this article.

Unlike conventional therapy that relies on high doses of calcium and active vitamin D, YORVIPATH directly addresses the root cause of the disease. The goal of treatment with YORVIPATH is to maintain serum calcium levels in the normal range without the need for active vitamin D or therapeutic calcium doses. However, patients can continue taking calcium supplements as needed to meet their daily dietary requirements.

To assist patients in starting and continuing treatment, the Ascendis Signature Access Program® (A•S•A•P) offers patient support with treatment initiation, insurance issues, and ongoing adherence. This program provides services to eligible patients prescribed YORVIPATH for its approved indication.

IMPORTANT SAFETY INFORMATION AND USE

What is the most important information I should know about YORVIPATH®?

YORVIPATH may cause serious side effects, including:

  • High levels of calcium in the blood (hypercalcemia). YORVIPATH can cause some people to have higher blood calcium levels than normal. Your healthcare provider should check your blood calcium before you start and during your treatment with YORVIPATH. Tell your healthcare provider right away if you have nausea, vomiting, dizziness, feeling thirsty, confusion, muscle weakness, or irregular heartbeat. Hypercalcemia is more likely to occur within the first 3 months of starting YORVIPATH, but it may occur at any time.
  • Low levels of calcium in the blood (hypocalcemia). People who stop using, miss, or change a dose of YORVIPATH may have an increased risk of low blood calcium levels, but hypocalcemia may occur at any time. Tell your healthcare provider right away if you have tingling in your fingertips, toes, lips or tongue, muscle spasms or cramps, oral numbness, depression, have problems thinking or remembering, abnormal heart rhythms, or seizures.
  • Possible bone cancer (osteosarcoma). Tell your healthcare provider right away if you have pain in any areas of your body that does not go away or any new or unusual lumps or swelling under your skin that is tender to touch. These are some of the signs and symptoms of osteosarcoma and your healthcare provider may need to do further tests.

Who should not take YORVIPATH?

Do not use YORVIPATH if you are allergic to palopegteriparatide or any of the other ingredients in YORVIPATH.

What should I tell my healthcare provider before taking YORVIPATH?

Before using YORVIPATH, tell your healthcare provider about all of your medical conditions, including if you:

  • are at higher risk of a type of bone cancer called osteosarcoma. This is especially important:
    • if you have a bone disease that increases your risk of developing osteosarcoma (including if you have Paget’s disease).
    • if a blood test shows that you have unexplained increases in bone alkaline phosphatase.
    • if you have cancer of the bones or other cancer that has spread to your bones.
    • if you are having or have had radiation therapy to the skeleton.
    • if you are affected with a condition that runs in your family that can increase your chance of getting cancer in your bones.
  • take medicines that contain digoxin, are used to treat osteoporosis, or can affect calcium levels in your blood.
  • are pregnant or plan to become pregnant. It is not known if YORVIPATH will harm your unborn baby. Tell your healthcare provider if you become pregnant during treatment with YORVIPATH.
  • are breastfeeding or plan to breastfeed. It is not known if YORVIPATH passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with YORVIPATH.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. YORVIPATH and other medicines may affect each other causing side effects.

What are the possible side effects of YORVIPATH?

YORVIPATH may cause serious side effects:

  • Allergic (hypersensitivity) reaction, including anaphylaxis. Stop taking YORVIPATH and tell your healthcare provider or get emergency medical help right away if you have swelling of your face, lips, mouth, or tongue, breathing problems, fainting, dizziness, feeling lightheaded (low blood pressure), fast heartbeat, itching, rash, or hives.
  • Decrease in blood pressure when you change positions (orthostatic hypotension). Some people may feel dizzy, get a fast heartbeat, or feel light-headed right after injecting YORVIPATH. For the first few doses, give your injection of YORVIPATH in a place where you can sit or lie down right away if you get these symptoms. If your symptoms get worse or do not go away, contact your healthcare provider before you continue using YORVIPATH.
  • Digoxin toxicity if you are using digoxin and YORVIPATH at the same time. Tell your healthcare provider if you experience irregular heart rhythm, heart palpitations, confusion, loss of appetite, nausea, vomiting, diarrhea, or vision problems.

The most common side effects of YORVIPATH include injection site reactions, vasodilatory signs or symptoms such as a drop in blood pressure or lightheadedness when standing up, headache, diarrhea, back pain, high calcium levels, and sore throat.

These are not all of the possible side effects of YORVIPATH. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA www.fda.gov/medwatch. You may also report side effects to Ascendis Pharma at 1-844-442-7236.

What is YORVIPATH used for?

YORVIPATH is a prescription medicine used to treat adults with low parathyroid hormone (PTH) (hypoparathyroidism).

  • It is not known if YORVIPATH is safe and effective in people who have been recently diagnosed with hypoparathyroidism after surgery, or if it is started in people with low levels of calcium in the blood.
  • It is not known if YORVIPATH is safe and effective in children.
  • YORVIPATH should not be used in children and young adults whose bones are still growing.

Please click here for full Prescribing Information for YORVIPATH and Medication Guide.

For more information about YORVIPATH, please visit www.yorvipath.com or call +1 844-442-7236.

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4 realistic resolutions for working parents to consider in 2025

2025-01-30T10:33:00

(BPT) – The 2024 U.S. Surgeon General’s Advisory shed light on the immense amount of stress parents are under. Part of this is due to the pressure that comes with raising children, working and wanting to be a high performer in every aspect of life. With the new year in full swing, now is a great time to make small, attainable resolutions that have the power to lower stress levels, enhance well-being and improve family dynamics.

“Letting your child see you relax, play and take things a little less seriously is a great way to model behavior that they can emulate someday,” said Joy Turner, vice president of education at Kiddie Academy®.

Here are a few realistic resolutions to help you get started:

1. Find out what your child is learning in school and connect it to your life at home.

A conversation with your child care provider is an easy way to extend what your child is learning beyond the walls of the classroom. For example, if you know the curriculum is highlighting bears one week in school, you can base your home activities around that same learning. Make a “bear snack” of apples dipped in honey, build a “bear cave” out of blankets or simply crawl around on the floor growling like bears. Transferring learning greatly benefits your child and takes the guesswork out of at-home playtime while supporting continued development.

2. Spend more time playing.

According to research from Kiddie Academy, 56% of parents indicate that they feel guilty for not spending enough time with their children, while 26% struggle to teach things like critical thinking skills, helping their little ones create connections with others (25%) and building confidence (23%). All of these skills can be learned through child-led play where your child’s imagination is left to wander and create. Instead of feeling the need to schedule structured activities, take this as an opportunity to enjoy the learning-through-play process with your little one.

3. Read one book a day with your child at home.

One of the most beneficial things you can do at home for your child’s education is to read at least one book together every day. According to research from The Ohio State University, children whose parents read to them on a daily basis hear nearly 300,000 words by the time they turn five years old. By reading more with your child this year, you’ll not only contribute to their healthy development, but you’ll also get to spend extra quality time together.

Setting a quiet family reading time each day is another beneficial practice — for both children and parents. During this time, bring out developmentally appropriate books, like “I Spy” for children who can’t read independently yet and early reader books for older children, and grab a book for yourself as well.

4. Give yourself a break.

Including your child in more tasks around the house that you would typically complete alone can help teach responsibility and independence that can eventually alleviate some of the parental workload. While it might take a little time at the start, your little ones can help with small tasks like putting laundry in the hamper and cleaning up toys.

Don’t forget to take a break from parenting — both physically and mentally. Schedule time to step away — even if it’s just taking an hour to do something for yourself before you pick up your child for the day — and remind yourself that you’re doing a good job.

“Working parents face unique challenges in managing their time and resources to take care of their families,” said Turner. “Leaning on their village, whether that’s family, friends or a child care provider, can help them balance the emotional and physical demands of parenting while freeing up time for them to enjoy being with their children.”

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How Type 2 Inflammation Contributes to Asthma, COPD, and Allergic Conditions

2025-01-29T09:01:00

(BPT) – Do you live with persistent, moderate-to-severe asthma, COPD, allergies, eczema or hives? Inflammation is often a major factor in the severity of your symptoms. It could also be a factor if your condition is hard to treat. When inflammation is severe and causes difficult-to-control symptoms, it’s called Type 2 inflammation.

Type 2 inflammation could be the underlying cause of your condition. It could also be the reason you have more than one condition.

What is Type 2 inflammation?

Type 2 inflammation is an overactive immune response that causes excess inflammation in the body. It plays a key role in many allergic, respiratory and skin diseases.

Type 2 inflammation is believed to be caused by genetic and environmental factors. It can be triggered by allergens (pollen, mold, dust mites, or pet dander) and irritants (pollutants). It can also arise from viruses and bacteria, weather changes, stress or exercise. Sometimes inflammation may occur without an apparent trigger.

Health conditions that may be affected by Type 2 inflammation include:

Symptoms involving Type 2 inflammation vary depending on your condition. Chronic inflammation can lead to long-term symptoms and tissue damage if it is not well managed.

What is the science behind Type 2 inflammation?

Type 2 inflammation can be driven by high levels of antibodies called immunoglobulin E (IgE). It can also be driven by high levels of eosinophils, a type of white blood cell.

IgE is designed to help the body fight off allergens, certain irritants, and parasitic infections. It binds to immune cells such as mast cells and basophils that trigger the release of histamine and proteins called cytokines. This can cause Type 2 inflammation that is severe and chronic, especially in allergic conditions.

Other key cytokines (called IL-4, IL-5 and IL-13) recruit and activate the eosinophils. When there are too many eosinophils in the blood, they can contribute to severe or ongoing Type 2 inflammation.

How do you know if you have Type 2 inflammation?

If you think your condition is affected by Type 2 inflammation, talk with a doctor, preferably a specialist such as an allergist. Doctors can diagnose Type 2 inflammation through blood tests that measure IgE and eosinophil levels. High levels indicate that Type 2 inflammation is present.

If you have asthma or COPD, a breathing test for your lungs called fractional exhaled nitric oxide (FeNO) can also indicate Type 2 inflammation.

What treatments are recommended for Type 2 inflammation?

Medications are available for people with diseases caused or worsened by Type 2 inflammation. Biologics are increasingly prescribed to help treat these conditions. They are used when standard treatments like corticosteroids or antihistamines are not effective. Biologics work at the cellular level, with the goal of stopping symptoms before they can start. They aim to reduce the levels of IgE and/or eosinophils that cause inflammation in the body.

It’s important to work together with your doctor to decide what course of treatment is best for you. Consider the severity of your symptoms and discuss what previous medications or treatments you have tried. Your healthcare provider can help you find out if Type 2 inflammation is connected to your medical condition.

Learn more at Type2Inflammation.org.

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Want a luxury bathroom? Opt for modular designs

2025-01-29T06:01:02

(BPT) – Bathrooms are more than just a necessity of modern living. It’s true that they’re practical spaces, but practicality doesn’t mean you have to sacrifice luxury.

Creating a bathroom that combines functionality and luxury isn’t difficult if you use the right design principles. George Wahlgren, Director of Product Development of Robern — a manufacturer of bespoke bathroom furnishings and fixtures — has answered a few questions to shed some light on how incorporating modular designs and products into your bathroom can enhance the space.

What are the benefits of modular design for bathrooms?

Modular design can enhance the look and feel of any bathroom especially when creating personalized spaces. Robern was the first in developing and commercializing modular storage and styling systems. So, it will come as no surprise that our designers and engineers know a thing or two about the benefits of modular design for customers.

There are many advantages to using modular designs in building or renovating a bathroom. For example, modular bathroom features can help seamlessly integrate various design components — such as different textures, finishes, materials and colors — while maintaining a cohesive and polished look.

Modular designs also offer the flexibility to maximize space in a bathroom, creating a sense of openness and elegance, giving people a chance to enjoy the benefits of functionality and personal expression. That includes customizable lighting and integrated technology.

Robern is a leader in modular design and the luxury bathroom space. How would you describe the company’s modular design ethos?

Robern’s modular design ethos is rooted in a long history of delivering a sophisticated blend of luxury, functionality and personalization. We design, engineer and manufacture all modular products in-house, ensuring a meticulous level of quality and seamless integration across our lines.

It’s these elements of our design ethos that allow Robern to stand apart and deliver exceptional products and services for our customers. With a legacy of innovation and craftsmanship, every product we offer can help transform a bathroom into a refined sanctuary that inspires and elevates everyday life.

We’re also committed to a holistic approach by combining cohesive design elements with a suite of complementary products. Robern ensures that every bathroom feels thoughtfully unified, functional and luxurious.

What luxury bathroom trends or features do you expect to see in 2025?

This year, we’re going to see bathrooms go beyond the basics and become more dynamic, multifunctional retreats. Whether they incorporate saunas, dressing rooms, beauty stations or home fitness areas, these versatile spaces will focus on offering a holistic experience.

Along the same lines, wellness and relaxation will take center stage in bathroom design in 2025. The idea of the bathroom as a sanctuary is stronger than ever, with spa-like atmospheres creating an escape from the stresses of daily life.

A major part of the spa-ification of bathrooms relies on providing an immersive sensory experience. You’ll see more bathrooms with dimmable lighting systems, allowing users to adjust the color and intensity of light based on their mood or activity.

As part of the sensory experience, designers lean toward a mix of natural materials and finishes, offering clients textural variation. Whether that’s achieved through contrasting textures or carefully curated patterns, bathroom designs will trend toward richness and luxury.

In terms of colors, you’ll see more deep hues and gold accents. Statement hardware, like pieces from the Robern Islamorada collection, add a distinctive, artistic flair, giving the space a unique, customized identity.

What are some modular bathroom products you’re excited for customers to try?

There are plenty of products I could suggest, but I’ll stick to our bread and butter: cabinets. The Modular Cabinets M Series Reserve collection includes products that are sophisticated and versatile, raising the bar for bathroom storage and blending advanced technology with thoughtful design.

Customers should also take a look at our InLine 2.0 Lighting collection. Lighting can make a huge difference in the practicality and ambiance of a bathroom. Robern offers beautiful vertical and sconce lighting options to complement any design and flawlessly pair with our medicine cabinets and mirrors for exceptional design flexibility.

No bathroom would be complete without a vanity. Our Cartesian and Profiles modular vanities offer luxurious personalization that is specially made for your space.

The Cartesian line features wall-mounted, floating vanities with clean lines that are an ideal centerpiece for your bathroom. If you’re looking to add a little drama to your space, opt for statement pieces like the Profiles modular vanities.

I would encourage every customer looking at our products to use our 3D Visualizer tool. This intuitive design tool empowers users to envision and create their ideal bathroom sanctuary with precision and ease. The online tool can streamline your product selection, enhance your decision making and allow you to share your designs with contractors, designers or family members, ensuring everyone involved is aligned on the project vision for a truly luxurious bathroom.

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4 expert skincare tips to unlock and restore youthful skin with America’s #1 Most Awarded Retinol

2025-01-28T11:01:00

(BPT) – As you age, your needs change, and that includes your skincare. Gone are the oily, acne-prone skin issues of youth. Instead, you’re dealing with dry, dull skin and the onset of lines and wrinkles.

You can thank collagen for plump, youthful and firm skin. But as you become older, your collagen levels begin to break down, which can impact your skin’s elasticity and lead to visible creases and wrinkles. While you can’t stop the hands of time, you can restore your collagen levels with the right skincare regimen. Check out these four tips below to help you get started:

1. Cleanse in the morning and at night

When making changes to your skincare regimen, begin by choosing a daily cleanser. An oil-based cleanser is ideal for mature skin as it cleans and hydrates without stripping the skin of its natural oils, which is crucial for drier and wrinkle-prone skin.

Your evening cleansing is even more important, as it’s crucial to cleanse your skin of makeup and pollutants at the end of the day and prepare your skin for your nighttime regimen.

2. Don’t skip SPF

No matter what stage you’re at in life, incorporating SPF products into your morning routine is essential for skin protection year-round and strongly recommended by dermatologists. Even if you don’t stay out in the sun often, protecting your face from UV/UVB ray damage can help prevent premature aging, sunburn, skin cancer, and collagen loss.

Choose a product with SPF 30 or higher, like RoC Retinol Correxion® Deep Wrinkle Daily Moisturizer SPF 30. Not only does the product protect the skin against harmful UVA/UVB rays, but it immediately hydrates the skin, and visibly reduces wrinkles in just 4 weeks. The moisturizer is made with pure RoC® retinol, America’s #1 Most Awarded Retinol*, which is clinically proven to reduce wrinkles without skin irritation.

Need more convincing to grab this daily staple? With over 5,000 5-star reviews on Amazon, one user called this product the “best facial moisturizer on the market,” with another stating “I couldn’t live without it.”

3. Exfoliate

Skin cell turnover also gradually declines as you age, making it harder for your body to get rid of dead skin. This accumulation of dead skin can make your face look dry and dull. Adding an exfoliant to your nighttime skincare routine can get rid of those flaky skin cells, improving the texture and clarity of your skin.

While your skin may have previously tolerated physical exfoliants like scrubs, these products may be too rough on more mature skin. Instead, opt for a chemical exfoliant to dissolve the dead skin cells, clean clogged pores, even out discoloration and minimize wrinkles.

4. Harness the power of retinol to treat lines and wrinkles while you sleep

At night, finish off your day and your skincare regimen with a night cream that uses retinol, such as RoC® Retinol Correxion® Deep Wrinkle Night Cream that deeply penetrates your skin as you sleep to hydrate and fight the appearance of deep-set wrinkles. During the day, your skin is exposed to environmental stressors such as oxidation and UV damage. However, at night, your skin is most receptive to cell renewal as it focuses on repairing damage, re-energizing the skin, and increasing collagen production.

Designed with pure RoC®Retinol, along with an exclusive mineral complex for additional hydration, RoC’s night cream is clinically proven to visibly reduce wrinkles for truly age-defying results. In 8 weeks, 93% of users saw a visible improvement in the appearance of deep wrinkles, and in 12 weeks, their wrinkles were visibly reduced by up to 50%.

“RoC® Retinol is clinically proven to be both stable and highly effective in reducing the appearance of fine lines and wrinkles,” said Dr. Marisa Garshick, Board-Certified Dermatologist. “Its gentle yet powerful formula is ideal for even first-time retinol users, offering an affordable option that fits seamlessly into any nightly skincare routine.”

Consistently incorporating RoC® Retinol into your routine means the treatment will be able to work through the night to deliver smoother, firmer and more radiant-looking skin each morning.

For an exceptional deal, grab both the RoC® Retinol Correxion Deep Wrinkle Daily Moisturizer and Deep Wrinkle Night Cream plus a bonus Hydrate + Plump Eye Cream for just $26.99 at Costco. You can thank us later.

*Based on a 3rd party study using publicly available data sources from publications and media sources hosting beauty awards since 2010.

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Resilience and Hope: Gail’s Journey with Multiple Myeloma

2025-01-28T08:01:00

(BPT) – For years, 69-year-old Gail from Houston has started her mornings with devotion and exercise. Her love for family and community shines through in everything she does as she dedicates her time to volunteering, reading, mentoring members of her church group, and nurturing her garden.

In 2010, everything changed. While on a trip, Gail felt a tingling sensation in her wrist but didn’t think much of it. On the way home, the tingling spread to her right shoulder and eventually developed into a deeper pain that would not go away.

“That’s when things began to change,” Gail says.

Once home, she sought medical attention. Her doctor ordered X-rays that identified lesions on her shoulder. She was quickly referred to a hematologist, who ordered blood work and a bone marrow biopsy. Gail was in shock when the doctors diagnosed her with multiple myeloma, a type of blood cancer where patients typically experience multiple relapses, with fewer treatment options available after each one.

In the beginning, Gail didn’t know what multiple myeloma was and had to advocate for herself and ask lots of questions of her care team.

“In those early days, I just wanted to get treatment and then get on with my life. I was scared, but I said to myself, ‘I’m going to beat it, whatever it takes.’ And I still have that mentality,” Gail says. “My doctor told me I probably wouldn’t live another five years, and I told her that would not be the case with me.”

Since her diagnosis, Gail often struggles with activities she loves given fatigue and other symptoms from her disease but maintains a positive attitude and hope about her future.

“I can still do the things I want to — I can go in my yard, look at my flowers and just enjoy them. For anyone dealing with this — don’t give up,” she says.

Nearly 14 years later, though, Gail is still living with and fighting this incurable disease.

“I love living, I love living well and I have learned so much about life,” she says.

The treatment landscape for multiple myeloma has changed significantly in recent years, with newer treatments like bispecific antibody therapies that are making a difference for patients and changing how the disease is treated.

Throughout Gail’s journey with multiple myeloma, she has experienced several relapses and has gone through multiple lines of therapy. Her doctor recently introduced TALVEY® (talquetamab-tgvs) to her treatment plan.

TALVEY® is a prescription medicine to treat adults with multiple myeloma who have already received at least 4 treatment regimens, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody to treat their multiple myeloma, and their cancer has come back or did not respond to prior treatment. TALVEY® is approved based on patient response. Data are not yet available to show if TALVEY® improves survival or symptoms. It is not known if TALVEY® is safe and effective in children.

TALVEY® is a bispecific antibody therapy, a type of medicine that targets two different proteins in the body. TALVEY® is the only therapy available that attaches to a protein called GPRC5D, which is found on multiple myeloma cells as well as some healthy cells in the body. It also binds to proteins called CD3 found on T-cells, a type of immune cell. Binding to both proteins may activate the immune system to help destroy the multiple myeloma cells. TALVEY® is available as an every-two-week or once-weekly subcutaneous injection after an initial step-up dosing phase. Once the patient and their care team have chosen a treatment plan, they begin a step-up dosing schedule where the patient receives the first 2 or 3 doses of TALVEY® at a smaller dose and increases up to the full treatment dose. Patients should be hospitalized for at least 48 hours after administration of all doses within the step-up dosing schedule, which allows them to be monitored for any potential serious or life-threatening side effects, including cytokine release syndrome (CRS) and neurologic problems. If you are being treated with TALVEY®, talk to your healthcare provider if you think you may be experiencing any signs or symptoms of a side effect.

TALVEY® was studied in 219 people with relapsed or refractory multiple myeloma who had previously been on at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody. People in the clinical trial received TALVEY® either as a once-every-two-weeks dose or once-weekly dose. 73.6% of patients receiving TALVEY® every two weeks responded to treatment. For patients receiving a weekly dose, 73% responded to treatment.

During her hospital stay for the initial step-up dosing phase of treatment, Gail’s care team supported her and answered her questions to make her feel comfortable and help prepare her for continued treatment on TALVEY®, and to educate her on the signs and symptoms of potential side effects. Gail has been on TALVEY® since December 2023, and her myeloma continues to respond to treatment.

“My doctor is happy with my recent test results. I love my doctor and appreciate that she’s very honest. I have so much confidence in her,” Gail says. “My doctor keeps telling me to keep up what I’m doing, and keep up my positivity and spirit. It’s like my personality is back.”

As a patient on TALVEY®, Gail recognizes that there are some challenges with being treated for multiple myeloma.

In addition to CRS and neurotoxicity, side effects that may occur with TALVEY® include mouth problems, such as taste alterations, dry mouth, weight loss, or skin changes. Along with working with your treatment team, the Leukemia & Lymphoma Society (LLS) has a tip sheet with recommendations on how to cope with common side effects affecting the mouth and skin with cancer treatment. For more information about being treated with TALVEY® and to access support and resources, including coping tips for patients, visit www.talvey.com.

“Side effects can be difficult and may be different for everyone. It is important to work with your treatment team to help manage them. You can do it,” Gail says.

Gail continues to share her experience with her myeloma support group and mentors others who are living with this disease.

“Mentoring is important to me because there are so many people hurting when they are diagnosed, and they don’t always see the light at the end of the tunnel,” Gail says. “You have to hear it from someone who knows what it’s like to live with this disease. And since I do, I want to share my experience with others so that they know there is hope. I live hope.”

Please review the Important Safety Information and see the full Prescribing Information including the Boxed Warning below. You can talk to your doctor if you have any questions. For more information, visit www.Talvey.com.

If one of Johnson & Johnson’s treatments has made a difference in your life or the life of a loved one, consider joining the SHARE Network. Every story is unique. If you or a loved one are living with multiple myeloma, your story could have the ability to provide hope and inspiration to other patients. To learn more about the SHARE Network and how to share your story, visit www.sharemyjanssenstory.com.

What is TALVEY® (talquetamab-tgvs)?

TALVEY® is a prescription medicine to treat adults with multiple myeloma who:

  • have already received at least 4 treatment regimens, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody to treat their multiple myeloma, and
  • their cancer has come back or did not respond to prior treatment

TALVEY® is approved based on patient response. Data are not yet available to show if TALVEY® improves survival or symptoms.
It is not known if TALVEY® is safe and effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TALVEY®?

TALVEY® may cause side effects that are serious, life-threatening, or lead to death, including Cytokine Release Syndrome (CRS) and neurologic problems.

Call your healthcare provider or get medical help right away if you develop any of the signs or symptoms of CRS or neurologic problems listed below at any time during your treatment with TALVEY®:

Cytokine Release Syndrome (CRS). CRS is common during treatment with TALVEY® and can also be serious or life-threatening. Signs and symptoms of CRS may include:

  • fever (100.4°F or higher)
  • feeling anxious
  • dizziness or lightheadedness
  • headache
  • chills
  • fast heartbeat
  • difficulty breathing

Neurologic problems. Symptoms of neurologic problems with TALVEY® may include:

  • headache
  • feeling sleepy
  • feeling confused
  • feeling very sleepy with low energy
  • being less alert or aware
  • slow or difficulty thinking
  • feeling disoriented
  • seizures
  • trouble speaking or writing
  • muscle weakness
  • shaking (tremors)
  • memory loss
  • numbness and tingling (feeling like “pins and needles”)
  • burning, throbbing, or stabbing pain
  • Due to the risk of CRS and neurologic problems, you should be hospitalized for 48 hours after all doses of TALVEY® that are part of the “step-up dosing schedule.” The “step-up dosing schedule” is when you receive the first 2 or 3 doses of TALVEY®, which are smaller “step-up” doses, and also the first full “treatment dose” of TALVEY®.
  • TALVEY® is given weekly or every 2 weeks. Your healthcare provider will decide the number of days to wait between your doses of TALVEY® as well as how many treatments you will receive.
    • If you receive TALVEY® weekly, “Step-up dose 1” is given on day 1 of treatment. “Stepup dose 2” is usually given on day 4 of treatment. The first “treatment dose” is usually given on day 7 of treatment.
    • If you receive TALVEY® every 2 weeks, “Step-up dose 1” is given on day 1 of treatment. “Step-up dose 2” is usually given on day 4 of treatment. “Step-up dose 3” is usually given on day 7 of treatment. The first “treatment dose” is usually given on day 10 of treatment.
  • If your dose of TALVEY® is delayed for any reason, you may need to repeat the “step-up dosing schedule” to receive TALVEY®.
  • Before each “step up” dose of TALVEY®, you will receive medicines to help reduce your risk of CRS. Your healthcare provider will decide if you need to receive medicines to help reduce your risk of CRS with future doses.
  • Your healthcare provider will monitor you for signs and symptoms of CRS and neurologic problems as well as other side effects, and treat you as needed.

TALVEY® is available only through the TECVAYLI® and TALVEY® Risk Evaluation and Mitigation Strategy (REMS) due to the risk of CRS and neurologic problems.

You will receive a Patient Wallet Card from your healthcare provider. Carry the Patient Wallet Card with you at all times and show it to all of your healthcare providers. The Patient Wallet Card lists signs and symptoms of CRS and neurologic problems.

Get medical help right away if you develop any of the signs and symptoms listed on the Patient Wallet Card. You may need to be treated in a hospital.

  • If you have any questions about TALVEY®, ask your healthcare provider.
  • Your healthcare provider may temporarily stop or completely stop your treatment with TALVEY® if you develop CRS, neurologic problems, or any other side effects that are severe.

See “What are the possible side effects of TALVEY®?” for more information about side effects.

Before you receive TALVEY®, tell your healthcare provider about all of your medical conditions, including if you:

  • have an infection
  • are pregnant or plan to become pregnant. TALVEY® may harm your unborn baby. Tell your healthcare provider if you become pregnant or think that you may be pregnant during treatment with TALVEY®.

Females who are able to become pregnant:

    • Your healthcare provider should do a pregnancy test before you start treatment with TALVEY®.
    • You should use effective birth control (contraception) during treatment and for 3 months after your last dose of TALVEY®.
  • are breastfeeding or plan to breastfeed. It is not known if TALVEY® passes into your breast milk. Do not breastfeed during treatment and for 3 months after your last dose of TALVEY®.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How will I receive TALVEY®?

  • TALVEY® will be given to you by your healthcare provider as an injection under your skin (subcutaneous injection), usually in the stomach area (abdomen). TALVEY® may also be injected into your thigh or another area of your body.
  • See “What is the most important information I should know about TALVEY®?” at the beginning of the Medication Guide for information about how you will receive TALVEY®.
  • If you miss any appointments, call your healthcare provider as soon as possible to reschedule your appointment.

What should I avoid while receiving TALVEY®?

Do not drive, operate heavy machinery, or do other dangerous activities during and for 48 hours after your TALVEY® “step-up dose” is completed or at any time during treatment with TALVEY®, if you develop dizziness, confusion, tremors, sleepiness, or any other symptoms that impair consciousness, until your signs and symptoms go away. These may be signs and symptoms of CRS or neurologic problems.

See “What is the most important information I should know about TALVEY®?” for more information about signs and symptoms of CRS and neurologic problems.

What are the possible side effects of TALVEY®?

TALVEY® may cause serious side effects, including:

  • See “What is the most important information I should know about TALVEY®?”
  • Mouth problems and weight loss. Tell your healthcare provider or get medical help right away if you develop any of the following symptoms of mouth problems:
    • changes in sense of taste
    • dry mouth
    • trouble swallowing
    • mouth sores

Your healthcare provider will monitor you for these symptoms and will monitor your weight during treatment with TALVEY®. Tell your healthcare provider if you lose weight during treatment with TALVEY®.

  • Infections. TALVEY® can cause serious infections that can be life-threatening and may lead to death. Your healthcare provider will monitor you for signs and symptoms of infection before and during treatment with TALVEY®. Tell your healthcare provider right away if you get or develop any signs or symptoms of infection during treatment with TALVEY®, including:
    • fever of 100.4°F (38°C) or higher
    • chills
    • cough
    • chest pain
    • tiredness
    • shortness of breath
    • painful rash
    • sore throat
    • pain during urination
    • feeling weak or generally unwell
  • Decreased blood cell counts. Decreased blood cell counts are common during treatment with TALVEY® and can also be severe. Your healthcare provider will check your blood cell counts during treatment with TALVEY®.
  • Skin problems. Skin problems are common during treatment with TALVEY® and can also be serious. Tell your healthcare provider if you get skin problems such as skin rash, raised red bumps, or redness of the skin.
  • Liver problems. Abnormal liver tests can happen during treatment with TALVEY®. Your healthcare provider will do blood tests before and during treatment with TALVEY® to check your liver. Tell your healthcare provider if you develop any of the following symptoms of liver problems:
    • tiredness
    • loss of appetite
    • pain in your right upper stomach area (abdomen)
    • dark urine
    • yellowing of your skin or the white part of your eyes

The most common side effects of TALVEY® include:

  • changes in your sense of taste
  • nail problems
  • muscle and joint pain
  • feeling very tired
  • weight loss
  • dry mouth
  • fever
  • very dry skin that may affect the mucous membranes (such as the mouth and eyes)
  • difficulty swallowing
  • infected nose, sinuses or throat (cold)
  • diarrhea

The most common severe abnormal lab test results with TALVEY® include decreased white blood cells and red blood cells. These are not all the possible side effects of TALVEY®.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Digital assets:

Please read full Prescribing Information, including Boxed Warning, for TALVEY®.

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For seniors: One simple step to protect your health and wallet in 2025

2025-01-28T06:01:00

(BPT) – Navigating the rising cost of prescriptions can feel like a challenge, but savvy seniors know there’s a smarter way to manage healthcare expenses in 2025. The new Medicare Prescription Payment Plan (M3P) offers a simple, stress-free solution to help retirees protect both their wallets and their health.

This innovative program that just launched January 1 allows Medicare Part D beneficiaries to spread out-of-pocket prescription costs into manageable, interest-free monthly payments throughout the plan year. With the Medicare Prescription Payment Plan, enrollees can avoid large bills at the pharmacy counter and still get the medications they need to stay physically and financially healthy.

A smart financial strategy

Managing healthcare costs in retirement is all about thoughtful planning. The Medicare Prescription Payment Plan provides the financial flexibility seniors need by allowing them to pay $0 upfront at the pharmacy and settle prescription costs in monthly installments. This makes budgeting easier and eliminates the financial strain of large, often unexpected, payments for medications. It’s especially helpful for anyone who will hit their $2,000 out-of-pocket cap early in the plan year.

Better health through access

Skipping medications due to cost is a dangerous gamble, and yet one in five older adults faces this reality. Staying consistent with medications helps manage chronic conditions and reduces the risk of serious health complications. The Medicare Prescription Payment Plan makes that possible by removing financial barriers to prescriptions so seniors can stick to treatments without interruption.

Peace of mind for you and your loved ones

The stress of managing large prescription drug costs can take a toll on mental and physical health. M3P brings peace of mind by offering predictable, manageable payments that more easily fit into monthly budgets. This program makes the process straightforward and stress-free both for seniors and those helping with their finances.

It all boils down to this: More control over finances, health and independence at zero cost.

“The Medicare Prescription Payment Plan is a major step toward ensuring seniors can access the medications they need without the burden of financial uncertainty,” said Brian Whorley, CEO of Paytient, one of the companies administering the Medicare Prescription Payment Plan. “This program isn’t just about affordability — it’s about giving individuals the peace of mind to focus on their health and independence, knowing their prescription costs are manageable and predictable.”

Ready to take the first step?

To participate, you’ll need to opt in. Learn more and sign up at Rx.Paytient.com. Starting in 2025, you’ll have the peace of mind that comes from knowing your prescription costs are under control.

Seniors don’t have to sacrifice financial stability or their well-being in 2025. Now is the perfect time to join this program and have assurance that prescription costs are under control.

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5 Ways to Stick to Your 2025 Healthy Commitments

2025-01-24T05:01:00

(BPT) – Research shows that by the start of February, up to 94% of people abandon the New Year’s resolutions they made. In fact, two separate dates have been coined “Quitter’s Day” and “Ditch Your Resolution Day.” Research shows that resolutions don’t typically work, but commitments do.

Reframing your mindset and aspirations can be the key to finding success. According to a recent national wellness survey of more than 1,000 people by Life Time, a national health and wellness company with more than 175 athletic clubs and a complimentary digital app, 74.7% plan to prioritize their health in 2025, a nearly 20% increase from last year. With that in mind, Danny King, Director of Recovery and Performance at Life Time, offers five unique and creative tips to help you move through the year with success, whether you work out at a health club or utilize a fitness app.

  1. Fulfill your interests: Look for a place or an app that offers programming to match your interests or goals now but also has variety to fulfill new aspirations or challenges as your comfort level grows. You may not think you can do a dance-based workout now, but you might want to in the future. The fun and novelty of new experiences can keep you excited about your workouts and goals. And trying a complimentary workout app can reduce intimidation too.
  2. Buddy up: Find a buddy who shares similar goals or try a small group training experience — this could be a current friend or someone new you meet. Multiple studies prove you’re much more likely to stick with a goal if you have a friend or a group to help keep you accountable.
  3. One step at a time: Challenge yourself with mini goals, like trying a new machine each week or steadily increasing the amount of weight you’re lifting. Check if your club or app offers progressive challenges to sign up for. For a leg up, Life Time has Dynamic Personal Trainers to support quicker gains (or losses) and keep you motivated.
  4. Fuel up: Find a health club with a café or smoothie bar and commit to trying something new and healthy. Life Time clubs have full fast-casual LifeCafe restaurants and an entire collection of pure, potent and powerful nutritional products and supplements that can also support your goals. And don’t forget the protein.
  5. Reward yourself: Many health clubs offer amenities like saunas, pools, cold plunges and massage services. Life Time is the largest operator of salons and spas in the country and can be used for daily care and as a reward for sticking to your workout routine. Treating yourself to a relaxing session can be a great motivator.

Regardless of your health and wellness goals, a commitment mindset and the right health club or fitness app will help you. Life Time’s free app with workouts, meditation, strength programs and more is available to anyone. King notes, “Whether in real life or digital, you want to look for a wide range of programs and services that are available for a variety of ages and abilities. We love this time of year when we can really help people find success.”

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Finding Strength in Words: María’s Rare Kidney Disease Story

2025-01-23T06:01:00

(BPT) – As a professional communicator, words have always come easily to María. That is until the diagnoses of two different rare kidney diseases that left María speechless.

Many people know what chronic kidney disease (CKD) is, but few people have heard of rare kidney disease (RKD). María lives with two different forms of RKD: IgA nephropathy (IgAN) and focal segmental glomerulosclerosis (FSGS). IgAN, one of the most common forms of RKD, causes inflammation in the kidneys, damaging their function over time. FSGS is characterized by the development of scarring in the kidneys. Both can lead to kidney failure in the prime of life.

An estimated 60-80 per 100,000 people in the United States currently live with RKD. RKDs are often diagnosed when people are younger and can progress faster than other forms of kidney disease. In fact, while people with RKD represent less than 5-10% of people with kidney disease, those with RKD represent upwards of 30% of those with kidney failure. As a result, people living with RKD face unique challenges navigating life with a rare disease. Due to low public awareness, people living with RKD often struggle to explain their condition to others.

A Change to Daily Life

This was the case for María, whose RKD caused many changes to her life in Mayagüez, Puerto Rico. Prior to her diagnoses in her early 30s, María was quite active, balancing a stressful job while raising a family, jumping to social activities, and enjoying travel. But after her diagnoses, she didn’t feel well enough or have the energy to keep up. This took a mental and emotional toll.

She felt alone, misunderstood and worried. Would her RKD cause kidney failure? How could she be there for her children and family? Would she be a burden to others?

Because her physical appearance remained unchanged, many people around her did not understand the impact that RKD had on María’s everyday life. “Unfortunately, if people don’t see something physically different about you, they don’t understand that you have a chronic condition,” she said.

Today, María surrounds herself with people who are helping her enjoy the most out of life, finding that “it is important to surround yourself with positive people” to create the best environment for life with RKD.

Strong Support System

María’s family is an important source of strength. Her mother and partner are two of her biggest pillars of support, and she also has a network of friends who keep her marching toward her goals and hopes for the future. Her father, who passed away years ago, still gives her strength as she remembers how he chose to live life with intensity and joy.

María’s children also motivate her to stay active and prioritize her health. “I want to be an example of perseverance for them, that we can never give up. We have to draw strength and continue with life.”

She also finds camaraderie and community from others living with RKD. “Being able to connect with people who are going through the same thing as me is important,” María said. “Although there are few of us, knowing that I am not the only one gives me the confidence to vent and to ask questions.” And that’s how she grew more comfortable talking about her rare kidneys and felt inspired to share her experience of living with RKD.

Finding Her Voice Again

When María learned about a campaign that aims to increase awareness of RKD through the power of storytelling, she felt like she found the perfect opportunity to tell her story about living with both FSGS and IgAN. Through RKD & Me, a campaign co-created by the IgA Nephropathy Foundation, NephCure and Travere Therapeutics, María penned a powerful letter to her younger self that captured the struggles she faced living with RKD, as well as the strength she found through her journey.

María hopes that by sharing the profound impact RKD has had on her life, she can help someone else living with RKD. “Being able to tell my story may help someone in need or who needs words of encouragement.”

If you have rare kidney disease and want to share your story or want to learn more about the experiences of people living with RKD, including María, visit RKDandMe.com or follow #RKDandMe on social media.