Posted on

Creative gifting: Luxurious bathroom presents that promote self-care

2023-11-12T23:01:00

(BPT) – The holiday season is synonymous with warmth, comfort and indulgence. This year, why not extend those feelings into the bathroom with luxurious gifts that elevate the everyday routines of your loved ones?

Gifting spa-worthy bathroom treasures will not only add a touch of opulence to your loved ones’ daily lives, but also provide a much-needed escape from the hustle and bustle of the holiday season. These gifts show you care and encourage wellness and a focus on self-care into the new year.

Feeling inspired? Here are some top trending ideas for unique, upscale gifts for the bathroom that any recipient will appreciate.

Shower scent systems

The Sprig Infusion System lets anyone transform their daily shower routine into a well-being ritual with specialized aromatherapy. This advanced device installs to an existing showerhead in minutes and then the recipient can choose a scent pod based on their mood and preference, like bergamot and lemongrass to recharge or chamomile and green tea to relax. These pods are mindfully created with clean ingredients that hydrate the skin and won’t leave surface residue on bathroom fixtures. It’s a unique gift that’s easy to use — simply pop these pods in the device and step inside the shower for a transformational showering experience.

Bath bombs and candles

Taking a bath is a time to relax, rejuvenate and everything in between. Rejuvenate the senses and elevate the bath by gifting elegant bath essentials that will make this holiday season a truly pampering experience. Sprig bath bombs are a must-have with 100% natural aromatherapy and self-care superstars like coconut oil, shea butter and kaolin clay. Pair bath bombs with candles in matching scents for an immersive aromatherapy experience that takes bath time to a whole new level.

Sumptuous towels and linen mists

When you visit the spa, one of the things you’ll notice is ample plush linens available in virtually every space. Fluffy and indulgent, a set of new luxury bathroom towels and other complementary linens make the ideal gift that will be used again and again. Enhance this gift with Sprig Body and Linen Mists that provide clean, natural and hypoallergenic botanical blends. Not only do these scents smell incredible, they are loaded with vitamins, minerals and antioxidants. Spray onto skin, clothing, linens, towels and more to delight the senses.

Customizable bidet seats

Get a luxurious, intimate clean every time you go to the bathroom when you add the Kohler C3®-050 bidet toilet seat to your existing toilet. Whether a gift to yourself or a loved one, this helps you stay clean and comfortable, with customizable warm water temperature and water pressure. The slim, low-profile design fits most elongated toilets and the self-cleaning stainless steel wand uses UV light for automatic cleaning.

Heavenly robes and slippers

When thinking of presents that pamper for that special someone, a tried-and-true classic is a luxurious robe and comfortable slippers. Whether heading into the day with a shower or winding down with a sensual soak, a robe and slipper set is a lovely gift that helps create a spa-like experience at home. For a custom gift with an elevated feel, consider monograming the robe or getting items in the recipient’s favorite color.

From top-quality aromatherapy products to sumptuous bathroom accessories, these luxurious gifts are bound to make the recipients feel like they’re being treated to a five-star spa experience right in the comfort of their own home.

Posted on

4 tips for staying on track with your nutrition goals during the holiday season

2023-11-12T23:01:00

(BPT) – This time of year, temptations are everywhere. From carb-laden office potlucks to family get-togethers where relatives beg you to sample their sugary desserts, sticking to your nutrition goals can be a tall order — but it is doable.

Colette Heimowitz, vice president of Nutrition and Education at Simply Good Foods Company, advises a sensible and manageable approach to the holidays.

“Holiday parties are meant to be enjoyed and a time to celebrate with friends, family and delicious food,” said Heimowitz. “There are ways you can make good choices and be prepared so you can avoid getting completely derailed from your wellness goals.”

Try some of her practical tips to help you stay on track this season.

  1. Contribute low-carb options to the next potluck. Bring your own Atkins-friendly recipes to potlucks or family gatherings to keep your body fueled with foods aligned with your nutrition goals. For example, the Atkins Low Carb Pumpkin Mousse Trifle is sweet, festive, easy to prep ahead, and will soon be a family favorite!
  1. Snack smart. Keep better-for-you snacks and treats close by, like the Atkins Endulge Crunchalicous Bars, which are sweet, crispy and packed with chocolatey flavor. With 1 gram of net carbs and 1 gram of sugar per serving, these are a fantastic addition to your holiday sweets rotation.
  1. Eat ahead. Arriving at a holiday party feeling famished makes it easy to overindulge. Instead, eat a small meal in advance, such as a protein source and a salad with olive oil dressing. Or grab a filling snack like veggies and guacamole to stabilize your blood sugar level and appetite. When you get to the party, seek low-carb, balanced options combining protein, healthy fats and high-fiber, nutrient-rich veggies.
  1. Keep hydrated. Thirst is often mistaken for hunger, so staying hydrated can help you avoid overeating. Find water boring? Add flavor with sliced lemons, limes or cucumbers.

“Research shows as you decrease your carb intake, your cravings for them will begin decreasing, so sticking to your health goals ahead of the holidays will help,” noted Heimowitz. “But be realistic. Enjoying a few bites of your favorite food is not the end of the world! You can always get back on track with your next meal.”

Find products and recipes for every occasion at Atkins.com.

Posted on

Cultivating community bonds: How farmers markets benefit growers and consumers

2023-11-10T12:01:00

(BPT) – Farmers markets are strong contenders for the future of local food. Each season, more than 8,000 markets sell directly to consumers across the U.S. Direct-to-consumer food sales totaled $2.9 billion in 2020, and on-farm stores and farmers markets accounted for $1.7 billion, according to the United States Department of Agriculture.

Farmers markets are a boon to local communities because they provide fresh produce at affordable prices. More importantly, they empower community members to understand where their food comes from and who grows it, creating strong interpersonal connections between growers and consumers.

The idea of selling produce at a farmers market can seem daunting to many food producers. However, Chip Ross, well-being program manager at Syngenta, encourages growers to be open to selling at farmers markets. “It’s certainly something to put yourself out there and build a positive reputation about your produce,” said Ross.

Investing money and labor to reap rewards

On average, across the country, farmers market booth fees vary based on the market’s location, size and popularity. According to Medium, daily booth fees can range from $20 to $50, in addition to permit and insurance fees. While these costs may discourage growers from participating, the connections they make at farmers markets can turn strangers into lifelong customers.

For 30 years, Donna and Ed Welchert of Ed Welchert Produce in Ft. Calhoun, Nebraska, have attended the Omaha Farmers Market every Sunday from May to October to sell their fresh vegetables. Each Sunday, the Welcherts spend three hours removing their produce from the truck and setting up their booth.

While the weekly setup requires more labor and costs, joining has brought them more business. “We pay an annual fee for our booth, around $1,100, and we’re in the same exact spot every week, every year, so everybody knows how to find us,” said Donna. “We’ve gained tons of customers who have been with us for years.”

Interacting with customers in person at the farmers market and through social media has helped the Welcherts build community connections. These connections allow consumers to get to know their growers on a personal level and reach out directly with any questions or requests.

Weather the weather, whatever the weather

Weather has a major effect on crop yields and food traffic at the farmers market, impacting growers’ sales. One common disadvantage is a lack of overhead booth coverings, which means harsh weather may damage booths, displays and products.

Zoua Lo, owner of Lu’s Flowers and Vegetables, knows all too well that sales are largely dependent on the weather. “If it’s a rainy day, we don’t have any customers. If it’s a nice day, we have lots of customers,” Lo said.

Despite being at the mercy of the weather, Lo and other growers persist. While selling at a farmers market can be a gamble depending on the weather, maintaining a consistent presence at the market long-term can offset the poor sales days.

The human element

Donna Welchert says when attending a farmers market, bringing ample produce is always a good idea. “A long time ago, we were told to ‘stack it high and watch it fly,'” she says. “We live by this motto, and we found that people want to pick out their own stuff. They want to look through the peppers and say, ‘This is the one I want.'”

By shopping at a farmers market, consumers can find the perfect produce with the guiding hand of those who nurtured the vegetable or fruit from seed to stall. It’s this human element that makes the farmers market experience unique for sellers and buyers and leads to better profits for growers.

Lo agrees. She believes the key to success at a farmers market is simply talking to customers and fellow vendors. Being friendly and connecting with the community builds long-lasting relationships that can buoy growers through good and bad days.

These are just a few examples from growers of how farmers markets are more than just a platform for commerce. These spaces are hubs for connection, education and community building that ultimately contribute to the longevity of farming communities.

To learn more about farm production and the wider agricultural community, visit SyngentaThrive.com.

Posted on

5 rivers that are perfect for small ship travel

2023-11-10T12:01:00

Photo courtesy Viking

(BPT) – Are you looking to travel differently in 2024? If you want a unique vantage point for learning about different parts of the world, exploring the small towns, iconic cities and countries along a river is sure open your eyes, heart and mind.

Did you know you can make the river the foundation of your travel plans by exploring via small ship with other like-minded travelers? No one does river cruises better than Viking, the small ship experts. These adults-only ships provide all of what you want — comfortable accommodations and ample opportunity to experience some of the world’s most interesting and significant rivers. And there’s none of the unnecessary flair — like the flashy casinos and tired art auctions of traditional cruises.

If the idea of river exploration inspires your wanderlust, here are five of the best rivers around the world that are perfect for exploring by way of a river voyage.

1. Rhine River

Photo courtesy Viking

From the Swiss Alps to the North Sea, the Rhine River flows through several European countries including Switzerland, France, Germany and the Netherlands. Raise a glass on Viking’s award-winning Longship while sailing the Rhine River and see how the historic river system unfolds to create a spellbinding display of storybook villages, Dutch windmills, German vineyards and splendid UNESCO sites. Enjoy Amsterdam’s charming canals and gabled houses, windmills of Kinderdijk, Cologne’s Gothic Cathedral, breathtaking views of the legendary Black Forest and much more.

2. Danube River

Photo courtesy Viking

From awe-inspiring cliffside castles to charming river towns, you’ll enjoy a trip of a lifetime when you explore the Danube River via small ship. Coursing through Germany, Austria, Hungary and seven other countries all the way to the Black Sea, the Danube is a key part of Central Europe’s rich and dramatic history. Just a few highlights you can see during a river cruise while exploring the Danube include the lush vineyards of the Wachau Valley, the baroque splendor of Melk Abbey, Vienna’s elegant architecture, Budapest’s stunning Chain Bridge, the soaring cliffs of the scenic Iron Gate and Belgrade’s impressive Kalemegdan Fortress.

3. Douro River

Photo courtesy Viking

Wine enthusiasts of all kinds will delight in small ship travel through the Douro River in Portugal that explores some of Europe’s oldest and most renowned wine regions and estates. Sip and savor divine food and beverage while enjoying the rich culture of this vibrant country on a Viking Longship, designed for elegance and comfort with all outside staterooms. From Lisbon’s stunning Manueline architecture and Vila Real’s extraordinary Mateus Palace to the hilltop fortress town of Castelo Rodrigo and the tiny village of Favaios, nestled among picturesque hills — you will fall in love with this incredible country and the river that has always helped sustain it.

4. Seine River

Bypass the basic and instead explore France in a unique way — via a river cruise on the Seine. Meander the river through medieval ruins, charming farms, elegant cities and much more. You’ll experience France’s culture and history in a way that will leave a lasting impression while in the comfort and style of an elegant river voyage. A few of the sights you’ll enjoy include the Eiffel Tower and Notre Dame Cathedral, Claude Monet’s beautiful house and gardens at Giverny, Normandy’s historic beaches and Château de Malmaison, Napoleon’s final home.

5. Mississippi River

There’s a reason it’s known as the mighty Mississippi: Stretching for 2,350 miles north to south in the United States, this river has transformed a nation’s history and culture. A great option for those who want to travel closer to home, you can sail through America’s heartland on one of Viking’s newest river ships that features all outside staterooms, private verandas and spacious public areas. The French Quarter in New Orleans, Graceland in Tennessee, Civil War history in Vicksburg National Military Park, and The Gateway Arch in St. Louis are just a few of the places you’ll experience on a Mississippi River voyage.

When wanderlust strikes, are you ready to travel differently and explore the world’s most memorable waterways? To learn more about these legendary rivers and exploring them via small ship, visit Viking.com.

Posted on

3 ways to help combat seasonal allergies

2023-11-10T09:01:00

(BPT) – If you regularly experience the symptoms of seasonal allergies, you know how miserable they can make you. The congestion, sneezing, runny nose and itchy eyes can really disrupt your daily routine. During the months when pollen counts are high for common allergens you are sensitive to, it’s a good idea to take some proactive steps to help reduce the presence of those allergens in your home, as well as your exposure to them.

Here are simple steps you can take that can make a big difference for your symptoms.

Stay updated on current pollen counts

Checking on the daily pollen counts in your area can help you make smart decisions around exposure for you and anyone else in your household who has allergies. On days when the counts are high, you may want to limit the time you spend outdoors, or wear an N95 mask if you do need to be outside for a while. This can help reduce your direct exposure to the pollen that’s floating in the air.

You’ll also want to make sure to keep all your windows closed on high pollen count days, and let the filter in your HVAC system (and any free-standing air purifiers you may use at home) get to work on keeping your home’s air as clean as possible. Regularly replacing filters is also a good idea — and even more frequently than manufacturers’ recommendations, if your allergies are severe.

Keep clothes and other items free from allergens

Did you know that you can help remove allergens from clothes and fabrics in your own home? With LG Styler® Steam Closet with TrueSteam® Technology and Exclusive Moving Hangers, you can keep all your clothing and any other items clean, refreshed and deodorized while also helping remove airborne allergens like pollen, pet dander and dust — without using any harsh chemicals.

The LG Styler Steam Closet is easy to install — all you need is a standard outlet — and has a slim design, so it’s easy to find a place to use it in your laundry room, bedroom or elsewhere in your home. TrueSteam Technology is a chemical-free steam-generating powerhouse that uses hot vaporized water to penetrate all kinds of fabrics. As the hot steam circulates, the hangers included will vibrate side to side to help shake out dust, allergens and odors.

Because of its effectiveness in helping remove airborne allergens, the LG Styler Steam Closet is certified by the Asthma & Allergy Foundation of America (AAFA). You can even use it for cleaning and removing pollen from hard-to-wash items including backpacks, stuffed toys, gloves, jackets and towels.

Even better, you can pair the LG Styler Steam Closet with Alexa or Google Assistant, or use the ThinQ App to download specialty care options, remotely check on remaining cycle time and more. Visit LG.com to learn more.

Reduce pollen, dander and dust on floors

It’s all too easy for allergens to settle on the floors throughout your home, so it’s best to keep them as clean as possible. If you can replace carpets with flooring that’s easier to keep clean, that is one recommended tactic. If not, use a vacuum cleaner with a HEPA filter to keep carpets clean, at least once or twice a week. Consider shampooing your carpet every two to three months to keep it as clean as possible, or you could hire a professional carpet cleaning service.

For hard surfaces, regular vacuuming and mopping can help keep airborne allergens from accumulating. Make sure to wear an N95 mask while you’re vacuuming to help protect yourself from dust, dander or pollen that gets kicked up while you’re cleaning.

You don’t have to be at the mercy of allergens, even on days when the pollen count is high. Following these strategies should help you reduce your allergy symptoms this season — and throughout the year.

Posted on

7 can’t-miss steps for Medicare annual enrollment

2023-11-10T09:01:00

(BPT) – It’s here — your yearly opportunity to make changes to your Medicare coverage. Medicare Annual Enrollment happens every year Oct. 15 through Dec. 7, during which you can review your current plan, compare your coverage options, and make any necessary updates. Any changes you make then go into effect on Jan. 1, 2024.

Whether you’re enrolling for the first time or not, it can be a lot of information to sift through. To help you stay organized and make sure you check every box, ClearMatch Medicare created the following handy checklist. Follow these steps to find the coverage that works for you.

1. Create a provider list.

Make a list of all your current medical providers, including your primary doctor as well as any specialists or services you use regularly. This should also include the clinics or hospitals you visit most. Listing this information will help you decide which Medicare plan is right for you.

2. List your prescriptions.

Do you take any prescription drugs? If so, write them down. Medicare plans change each year, and it’s possible that your current plan may stop covering your prescriptions. Have your medications top of mind before comparing plans for the coming year.

3. Plan ahead.

If possible, have a conversation with your doctor about what screenings, tests or medications you might need in the coming year. While you can’t see into the future, try to note any healthcare changes you expect over the next 12 months.

4. Review your plan’s Annual Notice of Change and Evidence of Coverage

If you have any coverage outside of Original Medicare (Parts A and B), your plan sends an Annual Notice of Change (ANOC) and Evidence of Coverage (EOC), which you should receive in September. If you don’t receive one, contact your plan. These documents provide details about upcoming changes to your coverage. Compare them to your current and projected medical needs to determine if it’s time to change plans.

5. Review your current Medicare and other insurance coverage.

Think about your existing plan. Is it meeting your needs? Are you OK with the cost? Reflect on what’s working and what’s not — then plan for any changes you need to make for next year.

And if you have other health insurance benefits besides Medicare, talk to your benefits administrator to determine how your Medicare enrollment impacts your additional health coverage.

6. Review Medicare Advantage options.

Many Medicare Advantage plans offer benefits not covered by Original Medicare, such as prescription drug coverage and routine dental and vision care. You may find that a Medicare Advantage plan saves you money thanks to this increased coverage. These plans also have a yearly out-of-pocket maximum, unlike Original Medicare.

7. Confirm your total cost.

The total cost of your Medicare plan may include monthly premiums, deductibles, co-pays and co-insurance. When comparing plans, dig a little deeper for an accurate picture of total costs so you’re prepared for the year and know what you can afford. Keep in mind:

  • For Part D plans, you need to consider the monthly premium, co-pays and the drug formulary. Most insurers use tiered pricing for prescription drugs. If your prescriptions are on one of the upper tiers, your co-pay could be substantial.
  • Most Medicare Advantage and Part D plans with extremely low premiums have higher co-pays, deductibles and out-of-pocket maximums.

Overwhelmed by all these steps? Don’t worry, free help is just a phone call away. ClearMatch Medicare is dedicated to making Medicare easier to understand so you can choose the plan that’s right for you. Their highly trained and licensed insurance agents are patient and helpful, and if they find you’re already in the right plan, they’ll tell you so.

Call 1-888-441-7382 (TTY:711) for a free Medicare review, Monday-Friday, 9 a.m.-9 p.m., Saturday, 9 a.m.-3 p.m. (ET) or visit ClearMatchMedicare.com, open 24-7.

Posted on

A Father’s Journey to Remission After Three Lymphoma Relapses

2023-11-09T12:01:00

(BPT) – Roy Bragadeste, a husband and father, was living in Seattle and enjoying what many would describe as a relatively normal life, working, spending time with his wife, kids and dog, and enjoying the outdoors. The idea of a cancer diagnosis was far from his mind, but that is exactly what happened.

During an epic storm blanketing Seattle with more snow than the city had seen in decades, Roy slipped and fell on a patch of ice, cracking three ribs. After experiencing severe pain for months from the broken ribs, he was examined by a doctor who pushed on his abdomen, causing Roy to call out in pain. Concerned that Roy shouldn’t be experiencing discomfort there, the doctor recommended that Roy undergo a CT scan, which showed a mass in his pelvis. Roy also had swollen lymph nodes, a common symptom of what would turn out to be an aggressive type of blood cancer called diffuse large B-cell lymphoma (DLBCL).

After undergoing a lymph node biopsy, Roy was diagnosed with this cancer of the lymphatic system, which occurs when abnormal white blood cells grow out of control.1 DLBCL is the most common type of non-Hodgkin’s lymphoma, responsible for approximately 31,000 new cases in the United States this year.2

Long before Roy moved to Seattle, he came to the United States from Portugal as an eight-year-old. His father, who did not yet speak English, worked three jobs, struggling to make ends meet. To help out his family, Roy started working at age 11, watering his neighbors’ yards for 75 cents each.

Helping support his family at a young age taught Roy determination and resilience, traits that would be important years later – not only when he was diagnosed with DLBCL but again when his cancer relapsed, not once but three times.

Facing the Challenge of a Lymphoma Diagnosis

DLBCL is a fast-growing blood cancer and one of the most aggressive types of non-Hodgkin’s lymphoma.3 For many people diagnosed with DLBCL, their cancer typically goes into remission with standard initial therapy. However, for 40% of them, their cancer either relapses (returns at a later time) or is refractory (doesn’t respond to initial treatment).4

Although Roy had advanced-stage DLBCL, his oncologist told him it was treatable.

“It took a few weeks to accept my diagnosis and see myself as a cancer patient in the fight of my life,” Roy said.

He was initially treated with a combination of chemotherapy plus immunotherapy, persevering through six cycles of therapy.

Roy was then referred to a hematologist at the Swedish Cancer Institute in Seattle who is a lymphoma specialist and received radiation treatment.

Experiencing the Burden of Relapse

When a PET scan showed Roy’s cancer had returned, the next step in his treatment journey was a bone marrow transplant.

“It was as close as I’ve ever been to saying ‘this is it, I’m done,’” Roy said, referring to his experience undergoing the bone marrow transplant.

Six months after returning home from the hospital from the bone marrow transplant, Roy felt pain in his hip and couldn’t lift his leg. His hematologist gave him the unfortunate news that the cancer had returned a second time. Roy elected to be treated with a type of cancer therapy in which immune cells were removed from his blood, genetically modified in a lab, and reinfused – which involved a week-long hospital stay.

Three months later, a scan showed a spot in Roy’s lungs, and biopsy results revealed the cancer had returned a third time.

“Every time I heard I had cancer again, it was just as bad as the first time I heard it,” Roy said.

Roy was worried he was out of options, but he followed his hematologist’s suggestion to enroll in a clinical trial evaluating an investigational treatment – a bispecific antibody, designed to utilize the immune system to fight lymphoma – for adults with DLBCL that has come back or did not respond to at least two previous treatments. It may also affect healthy cells.

“After I experienced a third relapse, I wanted to participate in a clinical trial. Even if the study wasn’t successful, I wished to give back by using my condition to help hematologists and researchers advance investigational therapies that might help other people in a similar situation,” Roy said.

Based on the clinical trial results, the Food and Drug Administration (FDA) approved the treatment, Columvi® (glofitamab-gxbm), under accelerated approval in June 2023 for adults with certain types of relapsed or refractory DLBCL or large B-cell lymphoma (LBCL) after at least two previous rounds of cancer therapy. All medicines have side effects. In the clinical trial of Columvi, a serious side effect that was common was cytokine release syndrome, a type of inflammation throughout the body that can be severe and life-threatening.

For people like Roy with aggressive lymphoma who have relapsed several times and have limited treatment options, Columvi may provide hope.

Columvi is what’s known as a fixed-duration treatment, meaning it’s given for a finite number of treatment cycles, which may allow patients to have time off therapy after completing treatment, rather than continuous therapy, which is given until the cancer progresses. Columvi is ready for infusion, so treatment may be able to start soon after the medicine is prescribed.

After Roy’s long treatment journey, he is now in remission. Today, he enjoys participating in outdoor activities and coaching baseball, and is focused on spending time with his family.

“Having blood cancer has been devastating, but it’s also been a blessing,” he explained. “It’s given me the opportunity to live like I was dying. I got a kick in the butt that told me to wake up!”

If you or a loved one has DLBCL, talk to your doctor about treatment options. For more information about Columvi, visit https://www.columvi.com/.

This sponsored article is presented by Genentech.

# # #

Columvi U.S. Indication

Columvi (glofitamab-gxbm) is a prescription medicine to treat adults with certain types of diffuse large B-cell lymphoma (DLBCL) or large B-cell lymphoma (LBCL) that has come back (relapsed) or that did not respond to previous treatment (refractory), and who have received 2 or more prior treatments for their cancer.

It is not known if Columvi is safe and effective in children.

The conditional approval of Columvi is based on response rate and durability of response. There are ongoing studies to establish how well the drug works.

What is the most important information I should know about Columvi?

Columvi can cause Cytokine Release Syndrome (CRS), a serious side effect that is common during treatment with Columvi, and can also be serious and lead to death.

Call your healthcare provider or get emergency medical help right away if you develop any signs or symptoms of CRS, including:

  • fever of 100.4°F (38°C) or higher
  • chills or shaking
  • fast or irregular heartbeat
  • dizziness or light-headedness
  • trouble breathing
  • shortness of breath

Due to the risk of CRS, you will receive Columvi on a “step-up dosing schedule”.

  • A single dose of a medicine called obinutuzumab will be given to you on the first day of your first treatment cycle (Day 1 of Cycle 1).
  • You will start the Columvi step-up dosing schedule a week after the obinutuzumab dose. The step-up dosing schedule is when you receive smaller “step-up” doses of Columvi on Day 8 and Day 15 of Cycle 1. This is to help reduce your risk of CRS. You should be hospitalized during your infusion and for 24 hours after receiving the first step-up dose on Day 8. You should be hospitalized during your infusion and for 24 hours after receiving the second step-up dose on Day 15 if you experienced CRS during the first step-up dose.
  • You will receive your first full dose of Columvi a week after the second step-up dose (this will be Day 1 of Cycle 2).
  • If your dose of Columvi is delayed for any reason, you may need to repeat the “step-up dosing schedule”.
  • If you had more than mild CRS with your previous dose of Columvi, you should be hospitalized during and for 24 hours after receiving your next dose of Columvi.
  • Before each dose of Columvi, you will receive medicines to help reduce your risk of CRS and infusion-related reactions.

Your healthcare provider will monitor you for CRS during treatment with Columvi and may treat you in a hospital if you develop signs and symptoms of CRS. Your healthcare provider may temporarily stop or completely stop your treatment with Columvi if you have severe side effects.

Carry the Columvi Patient Wallet Card with you at all times and show it to all of your healthcare providers. The Columvi Patient Wallet Card lists the signs and symptoms of CRS you should get emergency medical help for right away.

What are the possible side effects of Columvi?

Columvi may cause serious side effects, including:

  • Cytokine Release Syndrome.
  • Neurologic problems. Columvi can cause serious neurologic problems that may lead to death. Your healthcare provider will monitor you for neurologic problems during treatment with Columvi. Your healthcare provider may also refer you to a healthcare provider who specializes in neurologic problems. Tell your healthcare provider right away if you develop any signs or symptoms of neurologic problems, including:
    • headache
    • confusion and disorientation
    • difficulty paying attention or understanding things
    • trouble speaking
    • sleepiness
    • memory problems
    • numbness, tingling, or weakness of the hands or feet
    • dizziness
    • shaking (tremors)
  • Serious Infections. Columvi can cause serious infections that may lead to death. Your healthcare provider will monitor you for signs and symptoms of infection and treat you as needed. Tell your health care provider right away if you develop any signs of an infection, including: fever, chills, weakness, cough, shortness of breath, or sore throat.
  • Growth in your tumor or worsening of tumor related problems (tumor flare). Tell your healthcare provider if you get any of these signs or symptoms of tumor flare:
    • tender or swollen lymph nodes
    • pain or swelling at the site of the tumor
    • chest pain
    • cough
    • trouble breathing

The most common side effects of Columvi include: CRS, muscle and bone pain, rash, and tiredness.

The most common severe abnormal lab test results with Columvi include: decreased white blood cells, decreased phosphate (an electrolyte), increased uric acid levels, and decreased fibrinogen (a protein that helps with blood clotting).

Your healthcare provider may temporarily stop or completely stop treatment with Columvi if you develop certain side effects.

Before receiving Columvi, tell your healthcare provider about all of your medical conditions, including if you:

  • have an infection
  • have kidney problems
  • are pregnant or plan to become pregnant. Columvi may harm your unborn baby

Females who are able to become pregnant:

  • Your healthcare provider should do a pregnancy test before you start treatment with Columvi.
  • You should use effective birth control (contraception) during treatment and for 1 month after your last dose of Columvi. Talk to your healthcare provider about what birth control method is right for you during this time.
  • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with Columvi.
  • are breastfeeding or plan to breastfeed. Columvi may pass into your breast milk. Do not breastfeed during treatment and for 1 month after your last dose of Columvi.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while receiving Columvi?

Do not drive, operate heavy machinery, or do other dangerous activities if you develop dizziness, confusion, shaking (tremors), sleepiness, or any other symptoms that impair consciousness until your signs and symptoms go away. These may be signs and symptoms of neurologic problems.

These are not all the possible side effects of Columvi. Talk to your health care provider for more information about the benefits and risks of Columvi.

You may report side effects to the FDA at (800) FDA-1088 or http://www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

Please see Important Safety Information, including Serious Side Effects, as well as the Columvi full Prescribing Information and Medication Guide or visit https://www.Columvi.com.

References

  1. American Society of Clinical Oncology. Cancer.Net. Lymphoma – Non-Hodgkin: Introduction. https://www.cancer.net/cancer-types/lymphoma-non-hodgkin/introduction. Accessed June 28, 2023.
  2. Kanas G, Ge W, Quek RGW, Keeven K, Nersesyan K, Arnason JE. Epidemiology of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) in the United States and Western Europe: population-level projections for 2020-2025. Leuk Lymphoma. 2022;63(1):54-63. https://doi.org/10.1080/10428194.2021.1975188. Epub 2021 Sep 11. PMID: 34510995. Accessed June 28, 2023.
  3. American Cancer Society. About Non-Hodgkin Lymphoma. What Is Non-Hodgkin Lymphoma? https://www.cancer.org/cancer/non-hodgkin-lymphoma/about/what-is-non-hodgkin-lymphoma.html. Accessed June 28, 2023.
  4. Sawalha Y. Relapsed/refractory diffuse large B-cell lymphoma: a look at the approved and emerging therapies. J Pers Med. 2021;11(12):1345. https://doi.org/10.3390/jpm11121345. Accessed June 28, 2023.
  5. Columvi (glofitamab-gxbm) Prescribing Information. Genentech, Inc. 2023.

Posted on

The best regions of the world for small ship exploration

2023-11-09T14:01:01

(BPT) – You’re curious about the world, love to learn and want to travel in a way that uniquely connects you to the people, culture and landscape of an area. Small ship exploration checks all these boxes, providing you a closer look at what makes a region special so you have experiences that you’ll never forget.

Viking’s voyages offer highly curated, upscale travel experiences for adults on nimble small ships that explore some of the most incredible areas of the world. There are no kids, casinos, art auctions or umbrella drinks — because the focus is on the travel experience and exploring the world, which leaves a lasting and meaningful impression.

Here are the top regions to consider for small ship voyages and what you can expect to experience:

Scandinavia

Scandinavia is Viking territory and small ship exploration is the perfect complement to the region’s rich maritime history. From colorful fishing villages and breathtaking fjords to historic cities that feature rich cultural traditions, there’s so much to appreciate. On a Scandinavian voyage with Viking you’ll learn about the Hanseatic past of Bergen and traditional glassblowing techniques in Bornholm. You’ll have opportunities to experience a Sami ceremony north of the Arctic Circle and sheep farming in a Faroese village. Of course, you’ll be in awe of Norway’s magnificent fjords and perhaps catch a dazzling display of the northern lights during special winter sailings. Above all else, you’ll learn something new every day and be amazed at the world around you.

Caribbean and Central America

The rich cultural diversity and tropical climate has attracted travelers to the Caribbean and Central America for hundreds of years. Today, you can gain an intimate understanding of these legendary regions when you opt for small ship travel. In ports from San Juan to Colón, Viking’s Caribbean and Central America voyages allow for ample access to enriching excursions on land and sea. Just a few of the sights travelers enjoy are the soaring pyramids and temples of Chichén Itzá, picturesque rainforests of Costa Rica, natural wonders inside Bridgetown’s Harrison’s Cave, the fascinating history at the Mayan ruins at Belize’s Altun Ha and St. Lucia’s famed pair of volcanic pylons, Gros and Petit Pitons.

Mediterranean

The empires of the Mediterranean left a remarkable historic legacy that continues to influence today. Do you want to learn more and explore the area, but prefer to do so more like a local than a tourist? The secret is to go during the quiet season. With fewer travelers, you’ll get easier access to landmarks and easygoing interactions with locals. A variety of quiet season Mediterranean itineraries are available from Viking, so whether you want to admire the turquoise splendor of the Greek Isles, explore Rome’s monumental Colosseum, take in Vatican City’s glorious St. Peter’s Basilica or enjoy the architectural brilliance of Antoni Gaudi in Barcelona, you have plenty of options.

Great Lakes

The largest freshwater ecosystem on earth, the Great Lakes of North America offer a wonderland of nature just waiting to be explored. From the comfort of a Viking small ship, you can explore the Great Lakes, which total over 750 miles across with 10,000 miles of coastline. As you have breakfast, take in the beautiful and diverse landscape, and keep your eyes out for birds in the Great Lakes, you may even catch a glimpse of eagles. Depart the ship and try your hand at new adventures, like kayaking in Georgian Bay — a UNESCO Biosphere Reserve — or get closer to shore with one of Viking’s expert guides during a Zodiac excursion. Discover the powerful beauty of Niagara Falls, learn about Canada’s small mining towns, view the world-class collection of the Milwaukee Art Museum and so much more.

Grand Journeys

Feeling inspired? If you’re not sure which small ship journey to choose, you’ll be excited to learn you don’t have to settle for just one itinerary. Viking Grand Journeys combine two or more itineraries into one seamless trip through countries with rich histories, fascinating cultures and striking natural beauty. These longer, epic journeys allow you to explore the world in comfort and style, while learning from world-class guest lecturers, savoring regional cuisine and experiencing some of the most iconic cultural performing art forms around the globe.

To learn more about Viking and the many wonderful options for small ship travel, visit Viking.com.

Posted on

Medicare open enrollment help at no cost

2023-11-09T08:01:00

(BPT) – Medicare open enrollment ends on December 7. State Health Insurance Assistance Programs (SHIPs) provide free, in-depth, unbiased counseling and support to Medicare-eligible individuals, their families, and caregivers. Whether you are new to Medicare, reviewing Medicare plan options, or have questions on how to use your Medicare, a local SHIP can help. A certified counselor will give you one-on-one guidance based on your unique situation and needs.

Posted on

Gift Wrapping Weekend: The Ultimate Holiday Hack From Carter’s

2023-11-09T11:01:00

(BPT) – The holidays are just around the corner, and although it’s a magical time to spend with family and friends, it’s also one of the busiest and most stressful seasons for parents. So this year, Carter’s, the most trusted brand of apparel exclusively for babies and young children, is taking one of the most dreaded holiday tasks and turning it into something for parents to enjoy.

Inspired by last year’s viral social media trend, Carter’s is introducing its first-ever “Gift Wrapping Weekend,” rallying parents nationwide to dedicate the first weekend of December to tackling holiday to-dos while also indulging in self-care — think spa treatments, binge watching, cozy pajamas and more. The result? Two silent, relaxing nights away that allow parents to knock things off their to-do list and in turn, allows them to spend more uninterrupted quality time with their family during the remainder of the holiday season.

To kick off this epic new tradition, Carter’s is calling all shoppers to take advantage of its holiday deals and snag gifts early so they can spend Dec. 1 through 3 “wrapping up” their gifting to-dos in peace, and enjoy some much-deserved indulgence. The children’s clothing company is offering some of its best deals this time of year, including major discounts on Family Matching Holiday Pajamas and Family Holiday Outfits, plus check out the retailer’s Holiday Toy Shop for must-have gifts for your little ones. Not sure what to buy someone? Not to worry. Carter’s offers a slew of gift cards for all four of its brands so you can give the perfect gift, every time.

As an added bonus, Carter’s is kicking off the launch of its first-ever Gift Wrapping Weekend with an epic giveaway. Today through Nov. 14, parents and caregivers can enter Carter’s Gift Wrapping Getaway Giveaway for a chance to score a $2,500 gift card for a hotel stay to check in and check off holiday to-dos in peace, along with a custom wrapping kit. Nine runners-up will receive a wrapping kit complete with all the trimmings to jumpstart their weekend celebrations.

To enter, visit www.carters.com/wrappinggetaway and follow Carter’s on Instagram and TikTok for more updates this season. Shop Carter’s biggest holiday deals and steals on Carters.com, ensuring your little ones are fully dressed in festive fits this season.