Fight for your sight: 5 tips to fight Age-related Macular Degeneration

2018-02-08T16:01:00

(BPT) – The ability to see is one of our most precious gifts. Like most things in life, our vision may be impacted as we age. That’s why it’s important to learn about Age-related Macular Degeneration (AMD). Prevalent among older Americans, it affects one in five adults age 65 and older, and is the leading cause of blindness for this population. While there is no cure for this condition, there are steps that you can take to help reduce the risk of progression, including:

1) Schedule routine eye exams. As early stages of AMD may not present any symptoms, you may not think to consult your eye doctor. Keeping routine eye exams that include eye dilation may help to identify the condition early, as well as help maintain overall eye health.

2) Address symptoms immediately. See your eye care professional right away if you experience sudden or gradual changes in vision quality. As AMD progresses, straight lines may appear distorted, central vision may look dark, blurry or white, or changes in color perception may become noticeable. If you have been diagnosed with AMD, you should also regularly check your eyes with an Amsler grid tool that helps track incremental vision changes.

3) Lead a healthy lifestyle. If you smoke, quit. Regular exercise can also help to maintain eye health and minimize the risk of progression. Other risk factors for AMD include obesity, high cholesterol and high blood pressure.

4) Eat right. A diet rich in green, leafy vegetables as well as healthy fatty acids may also help reduce the risk of progression. Foods that contain these nutrients include: spinach, kale, broccoli, cabbage, romaine and chard, and fatty fish such as salmon, sea bass, herring, whitefish, mackerel, anchovies and sardines.

5) Consider supplements recommended by the National Eye Institute. If you’ve been diagnosed with moderate to advanced AMD, The National Eye Institute recommends taking a specific nutrient formula based on the AREDS 2 study, that may help reduce your risk of progression. Talk with your doctor to see if an AREDS 2 formula eye vitamin is right for you.

To raise awareness of this public health issue, Bausch + Lomb, in collaboration with Prevent Blindness, the nation’s oldest volunteer eye health and safety organization dedicated to fighting blindness and saving sight, has launched the Why Eye Fight campaign.

To learn more about AMD, what steps you can take to help fight for your sight or to watch the patient stories or PSA, visit www.WhyEyeFight.com. You can also join the online conversation and share your story using #WhyEyeFight on Facebook and Twitter.


Visit Durban for an unforgettable South African experience

2018-02-08T10:32:00

(BPT) – Think of South Africa, and images of majestic savannas and roaming wildlife come to mind. A South African safari is an unforgettable experience, but no visit to the country is truly complete without a cultural immersion. The vibrant city of Durban combines the best of both worlds. Located along the Indian Ocean coast an hour from Johannesburg by air, Durban offers an eclectic array of activities where you can explore the city’s significant role in world history, the rich heritage of its Zulu people, and innumerable natural wonders — from the beach to the bush.

Experience authentic Zulu culture

Named for its dramatic surrounding landscape, the Valley of 1,000 Hills has been home to the Zulu people, South Africa’s largest ethnic group, for centuries.

Visitors can take an organized tour deep into tribal lands to experience Zulu culture with its exuberant ceremonies, traditional music and dancing. You’ll learn about Zulu beliefs and healing practices, break bread with local families and learn the hidden meanings behind their colorful beadwork. You can even arrange one-on-one sessions with the village healer or spend the night with a Zulu family in their home.

Walk in Gandhi’s and Mandela’s footsteps

Not everyone is aware that Mahatma Gandhi’s life work was inspired by his experiences in Durban. In 1893, he arrived as a young lawyer, and the discrimination he witnessed personally and against his fellow Indians drove him to start his worldwide movement of passive resistance fighting for the rights of the Indian population. At the Phoenix Settlement, you will see Gandhi’s house and the printing press he used to publish his newspaper, The Indian Opinion. Many of the more than one million Indians living in the city make the pilgrimage to this historical site alongside visitors from around the world.

Five years after his death, Nelson Mandela remains South Africa’s most revered public figure. 2018 marks a year-long celebration of his life and what would have been his 100th birthday on July 18. Honor his work when you’re in Durban by visiting the Nelson Mandela Capture Site, at the exact spot where he began his “Long Walk to Freedom” after being arrested for anti-Apartheid activism in 1952. Visit the striking monument and educational exhibition walking you through Mandela’s life and role in establishing a democratic South Africa.

Hit the beach at Umhlanga Rocks

Umhlanga Rocks, Durban’s laidback beach village, is on a picturesque stretch of the Indian Ocean. It beckons visitors with a scenic promenade passing by local landmarks including Umhlanga Lighthouse and Whale Bone Pier. A walkable downtown makes dining and nightlife easily accessible from the area’s many boutique hotels and guesthouses, and opportunities to get on the water abound — from surfing to deep sea fishing, scuba diving, whale watching and kiteboarding.

Discover an underwater wonderland

Consistently rated one of the top warm water diving and snorkeling sites in the world, Aliwal Shoal is also the spot to get up close and personal with blacktip reef sharks. Those brave enough can swim or dive alongside these mysterious creatures in the open ocean, but viewing from inside a cage is always an option.

Experience a Big Five safari

Back on land, the South African bush is less than four hours away by car. Private game reserves offer high-end safari lodge accommodations, minimal crowds and optimal chances for getting the perfect photos of the “Big Five” — elephants, rhinos, water buffalo, lions and leopards. In iSimangaliso Wetland Park, a UNESCO World Heritage Site, hippos, crocodiles, pelicans and flamingos roam Lake St. Lucia, while elephants, giraffes and leopards inhabit the adjacent grasslands.

Visit www.durbanexperience.co.za to learn more.


7 things you didn’t know about adult vaccination in the U.S.

2018-02-08T10:31:00

(BPT) – Even though vaccines are one of the greatest health innovations of the last century, a new survey shows that among some adults in America there is a lack of awareness about the immunizations they need as adults.

According to an online survey of 1,000 American adults aged 18 years and older, there is a critical gap between awareness and action when it comes to vaccination.1

Adults should talk to their healthcare providers about the Centers for Disease Control and Prevention’s list of recommended adult vaccines. The best way to protect yourself and those closest to you is to vaccinate for life. So, ask your doctor if you are up to date on all your vaccines. It’s a simple step that can help protect you, your family and your community.

1. Adults may think they know, but they have no idea

Nearly half of adults consider themselves to be “very” or “quite” knowledgeable about vaccines,2 yet fewer than three in ten Americans are aware of the vaccines recommended for adults their age.1

2. Vaccines are not just for kids

Most of us are familiar with the importance of vaccination during childhood; however, vaccination is equally important throughout adulthood, as the immune system begins to decline with age.3 Immunosenescence, also known as age-related decline in immunity, significantly contributes to the susceptibility of older adults to serious, yet preventable conditions including: influenza, pneumonia and shingles.3 Despite this, 65 percent of adults are not fully up to date on their vaccines.1

3. Vaccines may help save your life

Six million deaths are prevented globally each year as a result of vaccination. If global vaccination rates increased, even more deaths could be prevented.4

4. Vaccination may prevent unnecessary death

Vaccine-preventable diseases can cause long-term illness and even death. In fact, 99 percent of the more than 50,000 deaths from vaccine-preventable diseases that occur every year in the U.S. are in adults.5

5. Vaccination may protect against more than just vaccine-preventable diseases

Vaccination can also protect against other health problems. In fact, vaccinating against the flu can also help protect people against heart attacks and stroke.6

6. Vaccine knowledge may supersede action

Despite longstanding recommendations for the use of many vaccines, adult vaccination rates remain low. In 2015, the flu vaccination rate for adults aged 19 and older was less than 45 percent, Tdap (Tetanus/diphtheria/pertussis) vaccination rate for adults was only about 23 percent, and shingles vaccination rate for adults 60 and older was just about 31 percent.7

7. Vaccination may impact all of us in unexpected ways

Medical costs related to vaccine-preventable diseases in older adults are high and are expected to grow substantially in the coming years. One study forecasts U.S. medical costs for Americans 65 and older in the Medicare population to be $4.74 billion annually by 2030 for just one vaccine-preventable disease.8


1 Vaccinate for Life consumer survey. Exploration based on Q9. Which of the following statements best describes how up-to-date you consider yourself to be on vaccinations. I am aware of the vaccines recommended to adults of my age and have received all of these recommended vaccinations. Total base all respondents n=1000.

2 Vaccinate for Life consumer survey. Exploration based Q4A. How knowledgeable do you consider yourself to be on adult vaccinations, also referred to as immunizations? Are you … very knowledgeable, quite knowledgeable, not quite knowledgeable, not at all knowledgeable. Total base all respondents n=1000.

3 American College of Physicians et al. Aging and Immunity: The Important Role of Vaccines, 2017. Available at https://www.acponline.org/system/files/documents/clinical_information/resources/adult_immunization/aging_and_immunity_guide.pdf.

4 Ehreth J. The global value of vaccination. Vaccine. 2003;21:596-600.

5 Rice HR, Varkey P. What immunizations should I offer to my patients? A primer on adult immunizations. J Assoc Physicians India. 2011; 59:568-72.

6 Hung IFN et al. Prevention of acute myocardial infarction and stroke among elderly persons by dual pneumococcal and influenza vaccination: a prospective cohort study. Clin Infect Dis. 2010; 51:1007–1016.

7 U.S. Centers for Disease Control and Prevention. Surveillance of Vaccination Coverage Among Adult Populations — United States, 2015. MMWR Surveill Summ. 2017; 66(11):1–28.

8 Varghese L et al. The temporal impact of aging on the burden of herpes zoster. BMC Geriatrics. 2017;17:30.


Poison safety tips to keep your family safe this winter

2018-02-21T15:01:00

(BPT) – According to the Centers for Disease Control and Prevention, there are approximately 2 million poisoning incidents per year within the U.S., and more than 90 percent of these occur within the home. This winter, keep your family safe by learning more about the potential for poisoning, how to prevent it and how to get help if an incident occurs, most notably by calling the Poison Help line at 1-800-222-1222.

Follow these tips to have a healthy and safe winter season:

1) Know which winter items are poisonous. There are many household items in use during the winter that may pose a specific poison risk, including antifreeze and snow salt.

Antifreeze is a poisonous liquid used in cars. It has a sweet taste that children and animals like. If even a little is swallowed, it can be harmful and can cause kidney damage and death. Keep antifreeze, household cleaners and all chemicals in the containers they came in with a tight cap and keep away from children and pets. Before throwing away an antifreeze container, be sure to rinse it with water and replace the safety cap.

Salt used on driveways and sidewalks in winter can harm a pet or child if eaten. Store such salt out of reach and in a locked cabinet.

2) Keep your home warm — and safe. Carbon monoxide (CO) is a poisonous gas that has no color, odor or taste. The risk for CO poisoning increases in the winter, as the use of fuel-burning devices increases. Sources of CO include gas furnaces, gas water heaters, gas stoves, gas ovens, kerosene space heaters, wood and gas fireplaces, wood-burning stoves, power generators and car engines. These devices make CO, primarily when they are not working properly or are not used in a properly ventilated space.

Signs of CO poisoning are similar to flu and other cold-weather-virus symptoms, including headaches, nausea, vomiting, dizziness and confusion. To prevent CO poisoning, have at least one CO detector in your home. The best places for a CO detector are near bedrooms and close to furnaces. Have your heating system, vents and chimney checked every year by experts. Always follow product instructions for installing and repairing appliances that burn fuel, and never burn charcoal inside a house or garage. Additionally, do not use a gas oven to heat a house or apartment or use unvented fuel-burning devices indoors. Finally, never run a car in a closed garage.

3) Don’t let winter cold and flu season become more serious. Be sure that all medication, including over-the-counter cold medicine, is kept in locked cabinets, away from children and pets. Also, avoid mercury poisoning by using digital thermometers instead of glass mercury thermometers, which can break in a child’s mouth. Stay with children when taking their temperature. Spilled mercury should be cleaned up properly as it is a hazardous waste.

4) Save the number, save a life. The Poison Help line is your first line of defense against poisoning deaths and injuries. By dialing 1-800-222-1222, you will be connected to a local poison center staffed by trained, professional experts who can help you right away. Save the number in your phone today so you have it if you need it. You can also visit the Poison Help website at www.poisonhelp.hrsa.gov for more information on poison prevention.


Bipolar I Disorder – It’s More Common Than You Think

2018-02-06T09:59:01

(BPT) – Bipolar I disorder is a condition that equally affects men and women, regardless of age, race, or ethnicity.1 Approximately 1.5 million adults in America are living with this disease, yet it’s a condition that’s still chronically misunderstood and often misdiagnosed.2 In fact, people with bipolar disorder may struggle an average of 10 years before they receive an accurate diagnosis.1 That’s why knowing and understanding the symptoms is so important.

“One of the biggest difficulties with diagnosis is the wide variety of ways in which the disorder can manifest itself,” said Gary Sachs, MD, Associate Clinical Professor of Psychiatry at Harvard Medical School. “Although every person with bipolar I disorder can experience it differently, these experiences do include features that fall into specific categories of identifiable symptoms.”

Whether you’re someone who has a history of mental illness or are concerned about a loved one who is struggling with their mental health, Dr. Sachs sheds light on bipolar I disorder and answers some important questions to help you better understand this condition.

What is bipolar I disorder?

Bipolar I disorder is a brain and behavioral disorder that causes unusual changes in mood, activity levels, energy, and judgment, impacting a person’s ability to carry out day-to-day tasks.3 Everyone has typical ups and downs, but in bipolar I disorder these can be more extreme. People diagnosed with bipolar I disorder have periods called “mood episodes,” which can be either manic, hypomanic, depressive, or mixed.3 Every patient experiences episodes differently, but it’s important to note that bipolar I patients have had at least one manic or mixed episode. When managing their condition, patients should keep an open dialogue with their healthcare providers.4

Can you tell me more about what it means to experience mania?

Many people know what it means to be depressed, but fewer understand mania. Someone experiencing manic symptoms of bipolar I disorder may have periods of unusually elevated feelings like extreme happiness, energy, or irritability. Some symptoms of manic episodes may include3:

  • Feeling unusually happy, excited, or energetic
  • Feeling restless, irritable, wired, or overreactive
  • Having racing thoughts, difficulty concentrating
  • Poor judgment with risk taking, indulging in impulsive behaviors, and having a heightened sense of self-importance

What does it mean to experience a mixed episode? Is it common?

Someone with bipolar I disorder can have a mixed episode when experiencing symptoms of mania and depression at the same time. Mixed episodes are more common than you may think. In fact, 40% of people living with bipolar I disorder have experienced a mixed episode, sometimes called a “mixed state.”5 Some of these symptoms include3:

  • Feeling overly energized, while feeling very hopeless
  • Feeling agitated, while having extreme changes in appetite, and having suicidal thoughts
  • Having racing thoughts, while feeling “slowed down” or experiencing a loss of interest in something once enjoyed

Can you treat bipolar I disorder?

There is no known cure for bipolar I disorder, but symptoms may be managed through treatment. It is important for patients to partner with their healthcare providers, so that, together, they can determine an appropriate treatment plan. This may include counseling, support groups, and medicine. In fact, recently approved atypical antipsychotics have provided additional options to help people living with bipolar I disorder.

VRAYLAR® (cariprazine) is a once-a-day prescription medicine that’s FDA-approved in adults for the acute treatment of manic or mixed episodes of bipolar I disorder.6 In clinical studies, VRAYLAR® was proven to help manage manic symptoms in adults with manic or mixed episodes associated with bipolar I disorder. VRAYLAR® showed significant improvement in overall manic symptoms compared to those who took a placebo (sugar pill). VRAYLAR® was not studied to measure symptoms individually, and is not approved to treat hypomania, depression, or depressive symptoms.

Every patient experiences symptoms differently and not all patients respond to treatment in the same way. That’s why it’s important for patients suffering from bipolar I disorder to actively engage with their healthcare provider to determine which treatment path is appropriate for them.

IMPORTANT RISK INFORMATION

What is the most important information I should know about VRAYLAR?

Elderly people with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) taking antipsychotic drugs are at an increased risk of death.

VRAYLAR may cause serious side effects, including:

  • Stroke (which can be fatal) in elderly people with dementia
  • Neuroleptic malignant syndrome (NMS): Call your healthcare provider right away if you have high fever; stiff muscles; confusion; changes in pulse, heart rate, or blood pressure; or sweating. These can be symptoms of a rare but potentially fatal side effect called NMS. VRAYLAR should be stopped if you have NMS
  • Tardive dyskinesia (TD): Tell your healthcare provider if you cannot control the movements of your face, tongue, or other body parts. These could be signs of a serious and sometimes permanent side effect called TD. Risk of developing TD and the chance that it will become permanent are thought to increase the longer a person takes the medicine and the more medicine a person takes over time. TD can develop even after a person has been taking the medicine for a short time at low doses. TD may partially or completely go away if you stop taking VRAYLAR. TD may also start after you stop taking VRAYLAR
  • Late-occurring side effects: VRAYLAR stays in the body for several weeks, even after you stop taking it, which could affect the timing of when you may experience side effects. Tell your healthcare provider if you have side effects (eg, uncontrolled movements of the body and face, muscle stiffness, or feelings of restlessness) as these may occur several weeks after starting or increasing dose of VRAYLAR
  • Problems with your metabolism, such as:
    • High blood sugar and diabetes: If you have diabetes or risk factors for diabetes (eg, being overweight or family history of diabetes), your blood sugar should be tested before you start VRAYLAR and regularly during treatment. Complications of diabetes can be serious and even life threatening. Tell your healthcare provider if you have symptoms such as feeling very thirsty or very hungry, urinating more than usual, or feeling weak
    • Increased blood cholesterol or triglycerides: Your healthcare provider should check your cholesterol and triglyceride levels before and during treatment
    • Weight gain: Weight gain has been reported with VRAYLAR. Your healthcare provider should check your weight before and regularly during treatment
  • Low white blood cell count: Low white blood cell counts have been reported with antipsychotic drugs, including VRAYLAR. This may increase your risk of infection. Very low white blood cell counts, which can be fatal, have been reported with other antipsychotics
  • Decreased blood pressure: You may feel lightheaded or faint when you rise too quickly from a sitting or lying position
  • Falls: VRAYLAR may increase risk of falls, which could cause fractures or other injuries
  • Seizures
  • Impaired judgment, thinking, and motor skills: Do NOT drive or use dangerous machinery until you know how VRAYLAR affects you. VRAYLAR may make you drowsy
  • Increased body temperature: VRAYLAR may make you more sensitive to heat. You may have trouble cooling off. Be careful when exercising or when doing things likely to cause dehydration or make you warm
  • Difficulty swallowing: VRAYLAR and medicines like it have been associated with difficulty swallowing

Who should not take VRAYLAR?

Do not take VRAYLAR if you are allergic to any of its ingredients. Get emergency medical help if you are having an allergic reaction (eg, rash, itching, hives, swelling of the tongue, lip, face or throat).

What should I tell my healthcare provider before taking VRAYLAR?

Tell your healthcare provider about any medical conditions and if you have or have had:

  • Diabetes or high blood sugar in you or your family
  • High levels of total cholesterol, triglycerides, or LDL-cholesterol; or low levels of HDL-cholesterol
  • Seizures or conditions that increase your risk for seizures
  • Low or high blood pressure
  • Low white blood cell count

Tell your healthcare provider if you are pregnant, or if you plan to become pregnant. Using VRAYLAR in the third trimester may cause uncontrolled movements of the body and face, muscle stiffness, or feelings of restlessness and/or withdrawal symptoms in newborn babies. A special program (National Pregnancy Registry for Atypical Antipsychotics) collects information on the safety of antipsychotic drugs, including VRAYLAR, during pregnancy. For information, contact the program at 1-866-961-2388 or visit http://www.womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/.

Tell your healthcare provider about all medicines that you take or have recently taken, including prescriptions, over-the-counter medicines, and supplements. VRAYLAR may affect the way other medicines work, and other medicines may affect how VRAYLAR works.

What are the most common side effects of VRAYLAR?

  • The most common side effects were uncontrolled movements of the body and face, muscle stiffness, vomiting, indigestion, sleepiness, and restlessness.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all possible side effects of VRAYLAR.

Please also see full Prescribing Information, including Boxed Warning, which are also available at www.vraylar.com and https://www.allergan.com/assets/pdf/vraylar_pi.

References

  1. Depression and Bipolar Support Alliance. Bipolar Disorder Statistics. Available at: http://www.dbsalliance.org/site/PageServer?pagename=education_statistics_bipolar_disorder. Accessed January 31, 2018.
  2. National Institute of Mental Health. Bipolar Disorder Among Adults. Available at https://www.nimh.nih.gov/health/statistics/prevalence/bipolar-disorder-among-adults.shtml. Accessed January 31, 2018.
  3. National Institute of Mental Health. Bipolar Disorder. Available at: https://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtml. Accessed January 31, 2018.
  4. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.
  5. Muneer, A. Mixed States in Bipolar Disorder: Etiology, Pathogenesis and Treatment. Chonnam Medical Journal. 2017 Jan; 53(1): 1–13. doi: 10.4068/cmj.2017.53.1.1.
  6. VRAYLAR® (cariprazine) [package insert]. Irvine, CA: Allergan USA, Inc.; 2017.

Allergan® and its design are trademarks of Allergan, Inc.

VRAYLAR® and its design are registered trademarks of Forest Laboratories Holdings Ltd., an Allergan affiliate.

Licensed from Gedeon Richter Plc.

© 2018 Allergan. All rights reserved.

VRA112771_v2 02/18

Low white blood cell count: Low white blood cell counts have been reported with antipsychotic drugs, including VRAYLAR. This may increase your risk of infection. Very low white blood cell counts, which can be fatal, have been reported with other antipsychotics

Decreased blood pressure: You may feel lightheaded or faint when you rise too quickly from a sitting or lying position

Falls: VRAYLAR may increase risk of falls, which could cause fractures or other injuries

Seizures

Impaired judgment, thinking, and motor skills: Do NOT drive or use dangerous machinery until you know how VRAYLAR affects you. VRAYLAR may make you drowsy

Increased body temperature: VRAYLAR may make you more sensitive to heat. You may have trouble cooling off. Be careful when exercising or when doing things likely to cause dehydration or make you warm

Difficulty swallowing: VRAYLAR and medicines like it have been associated with difficulty swallowing

Who should not take VRAYLAR?

Do not take VRAYLAR if you are allergic to any of its ingredients. Get emergency medical help if you are having an allergic reaction (eg, rash, itching, hives, swelling of the tongue, lip, face or throat).


7 ways to stay committed to your fitness goals

2018-02-20T13:01:00

(BPT) – In January, when many people make New Year’s resolutions to get fit, they’re full of energy and excitement to start and see results.

But by the end of February, that intensity and interest start to slip. Gold’s Gym has identified this as the Fitness Cliff, or the time that gym check-ins begin to gradually decline.

To help fight against the urge to slow down or quit, Gold’s Gym has declared Feb. 22 to be Commitment Day. On that date, Gold’s Gyms across the country will offer free workouts and classes along with resources to help people stay on track. But you can take action right now to make it easier to recommit to your fitness resolutions.

1. Create a plan

Everyone’s fitness journey is different, and with a personalized plan of attack, you’re more likely to get the results you want. Work with an expert to develop a routine that’s best for your current fitness level, body type, age and health history.

“Simply planning to make your resolution part of your schedule makes a significant difference,” says Dempsey Marks, a Gold’s Gym fitness expert. “Our lives can get very busy, so writing a weekly workout plan on Sunday that includes days, times and workouts will help keep you focused, organized and accountable.”

To help you get started, anyone who recommits to their goals on Feb. 22 at Gold’s Gym will receive a free 30-day fitness plan from a certified personal trainer.

2. Eat well

Just because you kill it on the treadmill or in the weight room doesn’t mean you can eat whatever you want with no consequences. Food is fuel — learn what to put into your body that will help it perform its best.

Remember, eating three to four hours before your workout will deliver energy to your muscles and help you avoid low blood sugar levels. And eating after a workout will replenish the fluids and carbohydrates your body just burned off.

3. Find an accountability partner

Having at least one workout buddy is good motivation to keep you showing up, push you to work hard and encourage you to keep striving toward your goals. Plus, it’s great to have someone to celebrate with when you reach those fitness milestones.

Commitment Day is the perfect time for you and a pal to get started — bring a friend in to Gold’s Gym for free workouts and classes on Feb. 22.

4. Be adaptable

We get it: Life happens. If you can’t make it to the gym because your car broke down or you’re traveling, it can be tempting to take a break from your fitness routine.

With a digital personal training app like GOLD’S AMP™, you’ll always have an option for workouts at home or on the road. You can choose a coach-guided workout — including outdoor walking and running workouts, stretching and bodyweight exercises — to take anywhere and pair it with the perfect exercise playlist.

5. Just breathe

A fit lifestyle doesn’t happen overnight; don’t get frustrated if things are slow to start or if you hit a plateau. Let yourself rest, think positively and be patient. Getting stronger takes time and effort, and you’re putting in the work that will lead to results later.

6. Avoid the comfort zone

If it’s getting too easy, it’s time to reassess your routine. Don’t be afraid to try a different piece of equipment, lift that heavier weight or join a new group exercise class.

“It’s easy to get stuck in your comfort zone because it’s comfortable!” Marks says. “But with fitness, it’s especially important to avoid the comfort zone to challenge your body in new and unique ways. Plan a new workout every other week by switching up the equipment and machines or go for that personal record. It’ll help to avoid boredom and lead to greater physical gains.”

7. Set an example

Your efforts don’t go unnoticed. Whether or not you realize it, you’re inspiring someone else with his or her own fitness. Use that to give yourself a boost when you need it.

Take Gold’s Gym Challenge winner Ellie Carter, whose two young sons were moved by her efforts to get back in shape.

“Every time we’d go to Gold’s, the boys would say, ‘We’re going to the gym, and Mommy is going to get strong,’” she says. “[Kids] do what we model, so I definitely want to keep encouraging fitness.”

Read Ellie’s success story and find more inspirational stories like it.


New Study Confirms Value of a Simple Blood Test to Help Doctors Quickly Diagnose Blockages in Patients’ Heart Arteries

2018-02-06T06:01:01

(BPT) – Chest discomfort. Heartburn. Tightness or pressure in the throat, jaw, shoulder, abdomen, back or arm. These are all symptoms of a common heart disease called obstructive coronary artery disease (CAD), also known as a blockage in the heart arteries. And it can be deadly. In fact, it often is.

Given how serious a disease this is, you need to know your options for an accurate diagnosis. There’s new evidence for a simple blood test that can help your doctor determine whether your symptoms are due to heart disease or something else, like heartburn caused by a spicy meal, anxiety due to stress, or a pulled muscle in the upper chest area. An emerging field of medical research called cardiovascular genomics has given doctors a new way to discover whether their patients’ symptoms are caused by obstructive CAD just by looking at a patient’s blood sample.

A recent substudy of the Duke University-run National Heart, Lung, and Blood Institute-funded PROMISE trial[1] gave further evidence that this simple blood test can be used to help doctors determine whether obstructive CAD is the cause of patients’ symptoms as well as to provide information about the potential for future heart disease events.

The test (known as the Corus CAD® blood test) incorporates age, sex and gene expression measurements into a single score that indicates a person’s current likelihood of having a significant blockage or narrowing in their heart arteries. Unlike a genetic test, which provides information about a patient’s future risk of disease, this test provides the likelihood of plaque buildup in the arteries right when the testing is done.

Dr. Andrew Waxler of Berks Cardiologists Ltd. tells us that “Heart disease is not only the number one killer in the U.S., it is also incredibly expensive. The traditional and common tests and procedures doctors use, including heart catheterizations, are expensive, though these are very valuable tools when used with the right people. The beauty of this simple blood test is it’s not very expensive, relatively speaking, and it will direct who needs the more expensive and more risky tests, and who doesn’t. This is a good thing because fewer invasive tests mean fewer risks to the patient, including surgery complications and radiation exposure.”

“In these current health care economic times, people don’t want to pay for unneeded tests. With proper use I feel this simple blood test will help us all save money in the long run while helping doctors determine the best treatment path for each individual patient. It’s a win-win for all involved,” adds Dr. Waxler.

This simple blood test is scored on a scale of 1-40. Those with low scores, defined as ≤ 15, can be safely assessed as having symptoms not caused by CAD, whereas patients with higher scores have a higher likelihood of obstructive CAD. A low score means the patient may be spared invasive and potentially risky cardiac tests and procedures, while those with high scores may require more testing.

If you are concerned about the symptoms of obstructive CAD, talk with your doctor.

For more information about the blood test, visit coruscad.com.

Fast Facts

  • One in seven deaths among Americans is caused by CAD.[2]
  • A simple blood test called Corus CAD helps doctors identify patients who are at low risk so that unnecessary and potentially harmful cardiac tests can be avoided, as well as those at high risk so appropriate next steps can be taken.
  • This simple blood test (Corus CAD) offers potential costs savings to the patient as well as to health insurance companies as it can help reduce unnecessary tests and procedures, which are often more costly.


[1] Voora D, Coles A, Lee KL, et al. An Age- and Sex-Specific Gene Expression Score is Associated With Revascularization and Coronary Artery Disease: Insights From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Trial. Am Heart J. 2017;184:133-140.

[2] Mozaffarian D, Benjamin EJ, Go AS, et al. On Behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics – 2016 Update: A Report from the American Heart Association. Circulation. 2016;133(4):e38-e360.


New Treatment Option for People With Cystic Fibrosis

2018-02-20T12:01:00

(BPT) – For patients with cystic fibrosis (CF) 12 years and older with certain mutations

At 17 years old, Taylor Brown is a straight-A student balancing a 10-hour work week and competitive dancing. She is also one of approximately 30,000 Americans living with cystic fibrosis (CF), a progressive genetic disease that makes it difficult to breathei.

Taylor has been taking a combination of medicines to treat and manage her disease since her diagnosis when she was six days old. In the U.S., approximately 1,000 people are diagnosed with CF each yeari. CF is a disease you are born with.

“Cystic fibrosis has always been a part of my life, but I don’t let it define me,” said Taylor. “I’m still able to do the things I love, like competitive dancing and advocating for other people with cystic fibrosis.”

There is no cure for the life-shortening disease, but therapies are available for some people that target the underlying cause of CFii. CF is caused by a reduction in the quantity and/or function of cystic fibrosis transmembrane conductance regulator (CFTR) proteins resulting from gene mutations that leads to the buildup of mucus in organs, such as the lungsi.

After talking with her treatment team and family, Taylor participated in a clinical trial for SYMDEKO™ (tezacaftor/ivacaftor and ivacaftor). SYMDEKO was recently approved by the Food and Drug Administration (FDA) for the treatment of cystic fibrosis (CF) in patients aged 12 years and older who have two copies of the F508del mutation or who have at least one mutation in the CF gene that is responsive to SYMDEKO.

“SYMDEKO is a new treatment option that helps the body’s CFTR proteins work better,” said Patrick Flume, M.D., Director of the Cystic Fibrosis Program at the Medical University of South Carolina. “Scientific innovations have enabled medicines to target cystic fibrosis at its root. I encourage patients and their families to work with their doctors to understand how these developments may help them.”

SYMDEKO is made up of two medicines that work to help increase the quantity and function of CFTR protein in certain people with CF. The FDA approval of SYMDEKO was based on results from two global Phase 3 trials in approximately 750 patients, which demonstrated the safety and efficacy of SYMDEKO in people with CF ages 12 and older who had certain mutations in the CFTR gene.

“I’m excited about new discoveries and research in cystic fibrosis, because they have a very real impact on my life and the lives of others with cystic fibrosis,” said Taylor.

Indication and Important Safety Information for SYMDEKO tablets (tezacaftor 100 mg/ivacaftor 150 mg and ivacaftor 150 mg)

What is SYMDEKO (tezacaftor/ivacaftor and ivacaftor)?
  • SYMDEKO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients aged 12 years and older who have two copies of the F508del mutation, or who have at least one mutation in the CF gene that is responsive to treatment with SYMDEKO.
  • Talk to your doctor to learn if you have an indicated CF gene mutation.

It is not known if SYMDEKO is safe and effective in children under 12 years of age.

Important Safety Information

Do not take SYMDEKO if you take certain medicines or herbal supplements such as:
  • antibiotics such as rifampin (Rifamate®, Rifater®) or rifabutin (Mycobutin®)
  • seizure medicines such as phenobarbital, carbamazepine (Tegretol®, Carbatrol®, Equetro®) or phenytoin (Dilantin®, Phenytek®)
  • St. John’s wort

Talk to your doctor before taking SYMDEKO if you take any of the medicines or herbal supplements listed above.

Before taking SYMDEKO, tell your doctor about all of your medical conditions, including if you:
  • have or have had liver problems
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if SYMDEKO will harm your unborn baby. You and your doctor should decide if you will take SYMDEKO while you are pregnant
  • are breastfeeding or planning to breastfeed. It is not known if SYMDEKO passes into your breast milk. You and your doctor should decide if you will take SYMDEKO while you are breastfeeding

SYMDEKO may affect the way other medicines work, and other medicines may affect how SYMDEKO works.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, because the dose of SYMDEKO may need to be adjusted when taken with certain medicines.

Especially tell your doctor if you take:
  • antifungal medicines such as ketoconazole (e.g., Nizoral®), itraconazole (e.g., Sporanox®), posaconazole (e.g., Noxafil®), voriconazole (e.g., Vfend®), or fluconazole (e.g., Diflucan®)
  • antibiotics such as telithromycin (e.g., Ketek®), clarithromycin (e.g., Biaxin®), or erythromycin (e.g., Ery-Tab®)
What should I avoid while taking SYMDEKO?
  • SYMDEKO can cause dizziness in some people who take it. Do not drive a car, use machinery, or do anything that needs you to be alert until you know how SYMDEKO affects you.
  • Avoid food or drink that contains grapefruit or Seville oranges while you are taking SYMDEKO.
What are the possible side effects of SYMDEKO?
SYMDEKO can cause serious side effects, including:
  • High liver enzymes in the blood have been reported in people treated with SYMDEKO or treated with ivacaftor alone. Your doctor will do blood tests to check your liver:
    • before you start SYMDEKO
    • every 3 months during your first year of taking SYMDEKO
    • every year while you are taking SYMDEKO
  • Your doctor may do blood tests to check the liver more often if you have had high liver enzymes in your blood in the past.
  • Call your doctor right away if you have any of the following symptoms of liver problems:
    • pain or discomfort in the upper right stomach (abdominal) area
    • yellowing of your skin or the white part of your eyes
    • loss of appetite
    • nausea or vomiting
    • dark, amber-colored urine
  • Abnormality of the eye lens (cataract) in some children and adolescents treated with SYMDEKO or with ivacaftor alone. If you are a child or adolescent, your doctor should perform eye examinations before and during treatment with SYMDEKO to look for cataracts.
The most common side effects of SYMDEKO include headache, nausea, sinus congestion, and dizziness.

These are not all the possible side effects of SYMDEKO. Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088.

Please click here to see the full US Prescribing Information for SYMDEKO.

To learn more about SYMDEKO, visit www.SYMDEKO.com.

i Cystic Fibrosis Foundation. About Cystic Fibrosis. Available at https://www.cff.org/What-is-CF/About-Cystic-Fibrosis/. Accessed February, 2018.
ii Pettit, RS and Fellner C. CFTR Modulators for the Treatment of Cystic Fibrosis. P T. 2014 July; 39(7): 500-511. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103577/.

© 2018 Vertex Pharmaceuticals Incorporated | VXR-US-23-00149 | 02/2018


5 tips from a tea expert to brew the perfect cup

2018-02-05T08:01:00

(BPT) – For most of us, a little evening downtime is not a luxury — it’s a necessity. After a hectic day of work, commutes, kids and dinner prep, we deserve to take a moment to slow down and enjoy some hard-earned “me time.”

Instead of using this time to stream your favorite show or scroll through social media, try a gentle and relaxing activity that puts your focus on the present moment and makes this time truly enjoyable.

“For a relaxing end-of-day activity, there’s nothing quite like preparing and savoring the perfect cup of herbal tea,” says Stephen Twining, whose family founded the world-famous tea brand, Twinings of London, in 1706.

The steps we take to prepare and enjoy our perfect cup of tea can help us unwind and feel refreshed, Twining says. Tea releases pleasing scents, the warm brew makes comforting sensations as we wrap our fingers around the mug and take sips, and there’s the deep and satisfying flavors of the tea itself.

Of course, when we’re engaged in a mindful activity, it’s that much easier to let go of daily stress and transition into a more relaxed state. Follow these five tips from Twining to brew your favorite cup of herbal tea, and try making this a part of your end-of-day ritual.

1. Start fresh: The perfect cup of tea starts with a clean mug and a clean kettle of fresh, cold water. Never reuse water that’s already been boiled, because that can weaken the tea’s flavor, Twining says.

2. Don’t over-boil: As soon as the water reaches a boil, it’s time to remove the kettle from the heat source.

“I never let the water over-boil because in doing so, you will cause the oxygen in the water to be reduced, making the tea taste ‘flat,’” Twining says. For that reason, he recommends not using a microwave to boil the water.

3. Savor the moment: Set the tea bag in the mug before you add hot water, pouring it directly onto the tea bag. Just then, it starts releasing its herbal scent, so make sure you take a moment to inhale and relax while enjoying the aroma. Twinings offers a range of herbal teas each expertly blended to provide the perfect balance of taste, flavor and aroma. For example, Buttermint has a refreshing blend of peppermint leaves combined with the creamy flavor of vanilla for a smooth taste and rich aroma, perfect for helping you unwind.

4. Wait for the perfect flavor: Many people make the mistake of thinking that once the brew darkens, it’s ready to drink. However, Twining says color merely washes off the tea leaves early in the process, so don’t let the appearance mislead you. To make sure the flavors fully develop, know how much time your tea needs to brew, and keep an eye on the clock. Herbal teas should steep for a full four minutes.

5. Customize and enjoy: Hopefully, you will find your perfectly brewed cup of herbal tea needs no embellishment because the expertly blended herbs and flowers will provide all the flavor you need. But as Twining says, “The best cup of tea is the one you like the most,” so feel free to make adjustments. The recommended add-ins for herbal teas are honey, sugar or a squeeze of lemon — do not add milk or cream. For a deeper flavor, let the tea steep a minute or two longer.

After a long day, you definitely earned this moment, so make sure you take time to enjoy it. If you’re interested in exploring Twinings’ complete line of herbal teas, visit twiningsusa.com.


5 things your doctor may not have told you about heart disease

2018-02-20T07:01:00

(BPT) – Every day your heart beats an estimated 100,000 times to move 2,000 gallons of blood through your body. That equates to more than 2.5 billion beats in your lifetime! It’s no surprise heart health is a priority for many people, especially considering that heart disease is so common.

One in four deaths in the United States is caused by heart disease. More than 610,000 people die of heart disease in the U.S. every year, making it the leading cause of death for both men and women, according to the Centers for Disease Control and Prevention.

You know you need to eat a nutritious diet, exercise and avoid smoking. However, there’s a lot more you need to know to protect yourself and your family. Consider these five surprising things your doctor may not have told you about heart disease.

Heart disease can be caused by a genetic disorder

You may never heard of familial hypercholesterolemia (FH), a common, but inherited genetic disorder that causes heart disease. FH affects approximately one in 250 people worldwide, but currently 90 percent of people born with this genetic condition are not diagnosed. Individuals with FH have a high amount of low density lipoprotein (LDL) or “bad” cholesterol in their blood from birth. This lifelong burden of cholesterol is a major reason why FH leads to very early and severe heart disease. The good news is that FH is manageable if detected and treated early in life. If high cholesterol and early heart disease runs in your family, learn more at thefhfoundation.org.

Many heart attacks occur outside the hospital

About 47 percent of sudden cardiac deaths occur outside a hospital, according to the CDC. This suggests that many people with heart disease don’t recognize or act on early warning signs.

Heart attacks have several major warning signs and symptoms:

  • Chest pain or discomfort.
  • Upper body pain or discomfort in the arms, back, neck, jaw or upper stomach.
  • Shortness of breath.
  • Nausea, lightheadedness or cold sweats.

Know the signs. Trust yourself. If you have any of these symptoms or sense something is just not right, call 911.

Heart disease affects young people

Many people think heart disease occurs in old age, but it can affect people of all ages. Even if you or your family members are 30 years old or younger, you could be affected, especially if you have risk factors like high cholesterol or a family history of heart disease. Keep in mind, each child with a family member with FH has a 50 percent chance of inheriting the disorder, which is present since birth. Untreated individuals with FH have up to a 20 times increased lifetime risk of early heart disease, yet 90 percent of people with FH are undiagnosed, according to the FH Foundation.

Children (even infants) can have high cholesterol

Many adults are regularly screened for high cholesterol, but it’s not as common for children to be screened, although the American Academy of Pediatrics recommends that all children between the ages of 9 to 11 be screened for high cholesterol. These guidelines also recommend screening for FH as early as age 2 years if there is a family history of high cholesterol, early heart disease or known FH. Talk to your children’s doctor about screening. FH is characterized by an LDL-C level of over 190 mg/dL in adults, or over 160 mg/dL in children. FH may also be confirmed with a genetic test, although this is not necessary for diagnosis.

You can maintain a healthy heart at any age

Being diagnosed with high cholesterol, heart disease or even FH is not a death sentence. Every person’s health considerations are unique, but by working with your doctor, you can come up with a plan to help manage your health and maintain the strongest heart possible. This could include lifestyle changes and medications to manage the LDL cholesterol level in the blood. The key is to keep asking questions, learn about your specific health needs and stay dedicated to your heart health plan.