Category: Brandpoint

2018-04-10T07:01:00

(BPT) – By Jamie Schanbaum, GSK spokesperson, U.S. Para-athlete and meningitis survivor

Before I contracted bacterial meningitis in 2008, I had never heard of it. I didn’t know how it was transmitted, what the symptoms were or how to help prevent it. After spending seven months in the hospital and losing all my fingers and both legs below the knee, I learned as much as I could about meningococcal disease. Now I want others to know what I didn’t.

1. Meningococcal meningitis, often referred to as meningitis, is an inflammation of the protective membranes, or meninges, covering the brain and spinal cord.^[1]
2. About one in 10 people carry the bacteria, Neisseria meningitidis, that can cause meningitis. These bacteria live in the back of the nose and throat. People who have the bacteria without any signs or symptoms of the disease are called “carriers.”^[2]
3. Meningitis is uncommon but can be fatal. About one in 10 people infected with meningococcal disease will die.^[3]
4. About one in five meningitis survivors will suffer long-term disability, such as loss of limbs (like me), brain damage, deafness and nervous system problems.^[4]
5. Young adults, including college students and those living in close quarters, are at increased risk for meningitis due to close contact with each other, sharing drinks or eating utensils, kissing or even just coughing.^[5],[6] I was 20 years old and in my first semester at the University of Texas when I contracted meningitis. I didn’t know about this increased risk.
6. Early symptoms may be similar to those of a cold or the flu, but can progress quickly and can be fatal, or cause disability within 24 hours.^[7],[8] Symptoms can include fever, headache and stiff neck as well as nausea, vomiting, sensitivity to light and confusion.^[9] Everyone’s symptoms can be slightly different, however. For example, I had nausea and vomiting, but also felt exhausted. My hands and feet were extremely sensitive to touching cold objects, like the sink faucet and tile floors. In just 14 hours, I went from thinking I had the flu to being admitted to the hospital. My experience may not be the same as others, so it’s important to know all the possible signs and symptoms and to seek medical help quickly.
7. There are five different vaccine-preventable serogroups of meningitis – A, B, C, W and Y. Groups B, C and Y are the most common groups of meningitis in the U.S.^[10]
8. There are two different types of vaccines needed to help protect against the five vaccine-preventable serogroups of meningitis.^[11] It’s important to know that even if you’ve had a vaccine for serogroups A, C, W and Y, you need a different vaccine to help protect against serogroup B.^[12]
9. Despite the availability of serogroup B meningococcal vaccination since 2014, less than 10 percent of teens and young adults have been vaccinated, even though serogroup B accounts for 30 percent of all meningitis cases in the U.S.^[13],[14]
10. The CDC says all 11- to 12-year-olds should be vaccinated against meningitis A, C, W and Y and recommends a booster at age 16. Additionally, the CDC says teens and young adults (ages 16 through 23) also may be vaccinated against meningitis B, preferably at 16 through 18 years of age. Though vaccination may not protect all recipients, it’s the best way to help prevent the disease.^[15],[16]

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2018-03-28T17:15:00

(BPT) – The kidneys play an important role in maintaining our overall health. While these bean-shaped organs perform multiple functions, a primary role is filtration, critical to clearing waste such as urea and to keeping the body’s fluids and electrolytes in balance. Good kidney health is essential for everyone, yet today, more than 30 million adults in the U.S. have chronic kidney disease (CKD), and there has been little new innovation to treat kidney disease in over a decade.[1]

So how does diabetes, an all-too-common cardiovascular and metabolic (CVM) condition, impact our kidneys? The most common causes of CKD are diabetes and high blood pressure.[2] For those with diabetes, the body does not make enough insulin or use normal amounts of insulin properly. Because of the high levels of sugar in the blood, the millions of tiny filtering units within the kidney are overused and damaged, leading to chronic loss of kidney function and, eventually, diabetic kidney disease. Diabetic kidney disease can lead to end-stage renal disease, which requires dialysis or kidney transplantation, further increasing the already elevated risk in diabetes for cardiovascular-related death.[3] Even with an estimated 1 in 3 people with type 1 diabetes and half with type 2 diabetes eventually developing CKD, there have been no recent breakthrough treatments for this disease.[4]

March is National Kidney Month, and it stands as a reminder of how important it is to not only take care of our kidneys and live a healthy lifestyle, but also to continue to research new ways in preventing, treating, and ultimately curing such life-threatening and widespread disease.

“Diabetic kidney disease continues to devastate communities worldwide, driven by rising diabetes incidence,” said James F. List, M.D., Ph.D., Global Therapeutic Head, Cardiovascular & Metabolism at Janssen Research & Development, LLC. “This condition is chronic and progressive with severe impact on a patient’s overall health and well-being. To have a meaningful impact on the fight against kidney disease, we need to focus our research on addressing diabetes, the primary cause of this disease.”

CKD often goes undetected until it is at an advanced stage. According to the National Kidney Foundation, the following steps can be taken to help protect the kidneys and improve overall health:[5]

1. Get tested: Ask your doctor for an albumin-to-creatinine ratio urine test, or a glomerular filtration rate (GFR) blood test annually if you have diabetes, high blood pressure, are over age 60, or have a family history of kidney failure.
2. Monitor and limit NSAIDs use: Pain medicines, such as NSAIDs (nonsteroidal anti-inflammatory drugs), may alleviate your aches and pains, but they can harm the kidneys.
3. Cut processed foods: Processed foods can be an unhealthy source of sodium, nitrates and phosphates, and have been linked to kidney disease, among other diseases.
4. Exercise regularly: Being active for at least 30 minutes a day can also help control lower blood sugar, which is vital to kidney health.
5. Control blood pressure and diabetes: Monitoring and managing blood sugar levels can slow the progression of kidney disease.

Kidney damage caused by diabetes can occur slowly and can go undetected over many years. However, you can take these easy steps to protect your kidneys, so act now.

2018-04-09T12:01:00

(BPT) – “As a doctor, I want patients to have open conversations with me about any symptoms they may experience without feeling uncomfortable,” said Dr. Howard Franklin, MBA, vice president of medical affairs and strategy at Salix Pharmaceuticals. “But, I understand that patients may sometimes choose not to talk about symptoms they find embarrassing.”

Such is the case when it comes to discussing bowel movements. For people who experience abdominal pain and diarrhea, it is important to discuss these symptoms with your doctor as they may be signs of irritable bowel syndrome with diarrhea (IBS-D).

A report published by the American Journal of Gastroenterology found that up to 75 percent of individuals living with irritable bowel syndrome may be undiagnosed. You are not alone.

For the up to 16 million Americans living with IBS-D, it is often an uncomfortable disorder that can reduce a patient’s quality of life. IBS-D affects twice as many women as men and often occurs in people younger than 45. It can cause interference with daily activities and avoidance of certain foods.

If you’ve experienced these symptoms, Franklin offers two important steps you can take.

Understand the disorder

IBS-D is a disorder of the large intestine and though the precise cause is unknown, it is believed that there are various factors that can play a role in creating symptoms. Stronger, longer muscle contractions in the intestines and poorly coordinated signals between the brain and the intestines are all possible causes for IBS-D. Often, IBS-D is triggered by food, caffeine, stress, carbonated drinks, artificial sugars or infectious diarrhea.

Changes in bacteria in the gut have also been linked to symptoms of IBS-D. In a healthy state, the microbiome and the human host have a mutually beneficial relationship as the host intestine provides the bacteria with an environment to flourish and the bacteria provides physiological stability. A change in the number of bacteria and in their type can disrupt this relationship.

Talk to your doctor

Don’t hesitate to initiate the conversation with your doctor if you experience symptoms of IBS-D.

It’s time to talk to your doctor if:

* Your abdominal pain keeps coming back at least one day per week in the last three months

* The frequency of your bowel movements, and/or the way your stool looks has changed

Here are a few ways you can prepare for a conversation with your doctor:

1. Write down your symptoms and triggers.

2. Make a list of all your medications.

3. Plan questions in advance, such as: What are the likely causes of my symptoms? Should I make any changes to my diet or lifestyle? What treatment options do you recommend for me?

There is no need to suffer with IBS-D in silence. Speak up to your doctor and, together, find ways to manage the disorder. For more information about IBS-D, visit www.LetsTalk-2.com.

2018-03-28T13:00:00

(BPT) – Carolyn Rios and her husband Rick have adventured far and wide together. From their post-college move to the Alaskan wilderness to 20 years of humanitarian work in Russia, this couple of more than 50 years has shared experiences that have far exceeded their imaginations.

Decades of adventure together — including a forced landing in their bush plane when its engine failed over a mountain range — have helped Carolyn and Rick learn to face and effectively manage unexpected challenges. But even as the two have come to expect the unexpected, nothing could have prepared the couple for Carolyn’s diagnosis at age 69 with the rare lung disease idiopathic pulmonary fibrosis, or IPF, in 2015.

“All of my emergency training could not equip me for the day Carolyn was diagnosed,” said Rick. “My initial thought was, ‘What do I do now? Where’s the emergency plan? How do we land this plane?’”

IPF causes permanent scarring of the lungs. It affects up to 132,000 Americans and yields about 50,000 new cases every year. A proper diagnosis for IPF patients often takes years because its symptoms, including breathlessness and a dry persistent cough, are similar to — and easily confused with — other more common and recognizable lung diseases, such as chronic obstructive pulmonary disorder (COPD) or asthma.

After Carolyn’s diagnosis, she experienced a period of deep concern for taking the next best steps — spiritually, emotionally and medically. Praying brought her comfort and clarity. Sharing the news with their two sons, family members and close friends brought support and companionship. The medical information seemed so bleak, yet her energy to pursue the next best steps remained. Thankfully, she and Rick were able to identify a pulmonologist who educated the two on Ofev^® (nintedanib), a treatment option that could help slow the progression of the disease.

Armed with information about IPF and potential treatment options, Carolyn and Rick started thinking about IPF as their next adventure and charted their course. Carolyn began taking Ofev^®, and Rick became her helper, assisting her to map out her daily regimen, track her medications and doctor appointments and follow a precise exercise and nutrition plan.

Today, Carolyn’s regular checkups have indicated only a slight drop in lung function. She experiences queasiness due to the medication but works with her doctors — her “adventure guides” — to manage this by eating certain foods prior to taking the medication.

“Life leads us on many adventures. Some adventures we plan, others are unexpected, and others challenge us more than we expect! But regardless, every adventure teaches us something if we’re willing to learn,” said Carolyn. “Experiencing IPF is another one of life’s adventures for me and accepting the challenges that come with it brings me to a deeper understanding of the true essence of my life. Each day still has opportunities to love well — with or without IPF.”

Carolyn and Rick are still able to travel together and most recently planned five trips for their 50th wedding anniversary — one trip to celebrate each decade of their adventure-packed marriage. And while their new “adventure” with IPF is ongoing, they are determined to focus instead on their time together and with their sons and grandchildren.

To learn more about Ofev^® visit www.Ofev.com.

What is OFEV?

OFEV is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF). It is not known if OFEV is safe and effective in children.

Important Safety Information

What is the most important information I should know about OFEV (nintedanib)?

OFEV can cause harm, birth defects or death to an unborn baby. Women should not become pregnant while taking OFEV. Women who are able to become pregnant should have a pregnancy test before starting treatment and should use birth control during and for at least 3 months after your last dose. If you become pregnant while taking OFEV, tell your doctor right away.

What should I tell my doctor before using OFEV?

Before you take OFEV, tell your doctor if you have:

• liver problems
• heart problems
• a history of blood clots
• a bleeding problem or a family history of a bleeding problem
• had recent surgery in your stomach (abdominal) area
• any other medical conditions.

Tell your doctor if you:

• are pregnant or plan to become pregnant.
• are breastfeeding or plan to breastfeed. It is not known if OFEV passes into your breast milk. You should not breastfeed while taking OFEV.
• are a smoker. You should stop smoking prior to taking OFEV and avoid smoking during treatment.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements such as St. John’s wort.

What are the possible side effects of OFEV?

OFEV may cause serious side effects.

TELL YOUR DOCTOR RIGHT AWAY if you are experiencing any side effects, including:

• Liver problems. Unexplained symptoms may include yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests regularly to check how well your liver is working during your treatment with OFEV.
• Diarrhea, nausea, and vomiting. Your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have these symptoms, if they do not go away, or get worse and if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements.
• Heart attack. Symptoms of a heart problem may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.
• Stroke. Symptoms of a stroke may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.
• Bleeding problems. OFEV may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal and/or if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.
• Tear in your stomach or intestinal wall (perforation). OFEV may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.

The most common side effects of OFEV are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

These are not all the possible side effects of OFEV. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/Safety/MedWatch/default.htm or call 1-800-FDA-1088.

For full Prescribing Information, including Patient Information, visit OFEV.com or contact Boehringer Ingelheim Pharmaceuticals at 1-800-542-6257

2018-04-09T08:01:00

(BPT) – A Simple Blood Test Can Help Doctors Determine Your Current Likelihood of Having a Blockage in Your Heart Arteries

Obstructive coronary artery disease (CAD), also known as a blockage in the heart arteries, has many telltale signs. Chest discomfort. Heartburn. Tightness or pressure in the throat, jaw, shoulder, abdomen, back or arm. Yet all these signs can signal other issues going on inside the patient. Too much spicy food, stress, a pulled muscle. The list can grow rather long. Determining the cause of these symptoms can be tricky business. So how do you and your doctor correctly identify the cause of your specific symptoms? It can be as easy as a simple blood test.

Understanding the results of the blood test is just as easy as getting the blood test done. This simple blood test is scored on a scale of 1-40. Those with low scores, defined as ≤ 15, can be safely assessed as having symptoms unlikely to be caused by CAD, whereas patients with higher scores have a higher likelihood of CAD. Patients with low scores can be spared invasive and potentially risky cardiac tests and procedures, while those with higher scores can receive additional testing necessary to achieve their proper diagnosis and treatment.

Recently, the results of the registry study, called PRESET,¹ looked at how effective the test does what it was designed to do. This simple blood test minimized unnecessary cardiology referrals and additional cardiac testing for low-risk patients. This means reducing patient exposure to radiation from a nuclear stress test or coronary CT scan, decreased likelihood of skin rashes where electrodes are placed for echocardiograms, electrocardiograms, exercise stress tests and more, reduced risk of dye reactions or risk associated with surgical heart procedures such as possible injury to the artery, kidney damage, bleeding complications, and more. These patients can get reliable information without the risks of the traditional tests.

The test (known as the Corus^® CAD blood test) incorporates age, sex and gene expression measurements into a single score that indicates a person’s current likelihood of obstructive CAD. Unlike a genetic test, which provides information about a patient’s future risk of disease, this test provides the current likelihood of blockage in his or her heart artery. It’s much safer for the patient and has the benefit of saving the healthcare system money by reducing unnecessary tests and procedures.

Recently, the American Heart Association highlighted the Corus CAD test in a new 2017 Scientific Statement² about how precision medicine can be used to diagnose and predict cardiovascular disorders. The AHA’s statement confirms that this simple blood test has been proven valid and useful in clinical studies. If you are concerned about the symptoms of obstructive CAD, talk with your doctor.

For more information about the Corus CAD blood test, visit www.corusCAD.com.

Fast Facts

• One in seven deaths among Americans is caused by CAD³
• Traditional tests carry various risks
• A simple blood test called Corus CAD helps doctors identify patients who are at low risk so that unnecessary and potentially harmful cardiac tests can be avoided, as well as those at high risk so appropriate next steps can be taken

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¹ Ladapo JA, Budoff M, Sharp D, et al. Clinical Utility of a Precision Medicine Test Evaluating Outpatients with Suspected Obstructive Coronary Artery Disease. Am J Med. 2017;130(4):482.e11-482.e17.

² Musunuru K, Ingelsson E, Fornage M, et al. The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association. Circ Cardiovasc Genet. 2017;10(4):e1-e25.

³ Benjamin EJ, Blaha MJ, Chiuve SE, et al. On Behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics – 2017 Update: A Report from the American Heart Association. Circulation. 2017;135(10):e146-e603.

2018-04-05T08:01:00

(BPT) – Whether it’s scrubbing through grime to reveal a sparkling surface, cleaning dust bunnies from under appliances or organizing your pantry, there’s something oddly satisfying about a deep clean.

According to a recent survey conducted on behalf of Clorox, lots of people get the good vibes flowing when it’s cleaning day. Seventy-one percent say it makes them feel relaxed, while 57 percent say they feel accomplished.

Of the most oddly satisfying places to clean in the house, 34 percent say they find their bliss after cleaning the countertops, while a clean microwave lends that special feeling to another 30 percent.

To reach that spring cleaning joy, try some of these not-so-obvious cleaning jobs that will transform the look and feel of your space into a springtime sanctuary.

Grout: Over time, mold and mildew buildup can make your bathroom grout look dingy, but with the right approach, the grout stains will disappear. Start by wetting the tile with a cloth. Then, dip a sponge into a gallon bucket of water with 3/4 cup of bleach and wipe down the tile. Wait five minutes for disinfecting, rinse and viola! Your tiles will shine, offset by the clean lines of white grout.

Microwave: We don’t like to think about it, but a lot of hard-to-remove food residue accumulates in our microwaves and we rarely spend the time to give it a thorough clean. Microwave a cup of water and in five minutes the steam will help loosen the stains. A Clorox Disinfecting Wipe will take care of those extra stubborn messes.

Dust: In addition to moving aside the beds, appliances and other heavy pieces of furniture to get those dust bunnies, make sure you’re tackling the not-so-obvious places. Use the vacuum’s brush attachment to clear your HVAC register vents and don’t forget to dust the tops of fan blades!

Windows: Those panes have taken quite a beating over the months. It’s time to get a soft sponge and a bucket of warm, soapy water to defeat the smudges and layers of dirt, and then wipe them clean with a squeegee. You’ll love how sparkling clean glass transforms the room.

Outdoor surfaces: Right outside your back door is a golden opportunity for a deep clean. Rent or borrow a pressure washer, and once it’s set up, you can enjoy watching the blast of water and degreaser effortlessly turn your concrete walkways and driveway into bright clean surfaces — like a magic wand. To easily remove the mold and mildew off your deck and patio furniture, add 3/4 cup of bleach to a gallon of water and swipe away the stains from seasons past.

Try these tips and enjoy basking in the satisfaction of a deep-cleaned house. To find the tools you need for the job, visit Clorox.com/satisfyingspringclean/.

2018-04-04T07:01:00

(BPT) – As a former professional football player and national sports talk show host, Mike Golic is constantly on the go. Living with type 2 diabetes means that Mike needs to take a few extra steps to manage his diabetes throughout the day. Here are a few tips that Mike uses to stay on track and find fun ways to help ensure a balanced diet and moderate exercise are part of his busy lifestyle.

Learn more about Mike’s story by visiting ICanImagine.com.

• Make healthy eating a priority. Mike knows he needs to fuel his body for the day ahead, so he always plans a healthy breakfast to help sustain his energy on and off the air. Having nutritious breakfast recipes on hand can help start the day off right. While Mike allows for the occasional indulgence, he focuses on healthy options throughout the day, stressing that moderation is key.
• Work in your workouts. After Mike gets home from co-hosting a great show, it’s time to work out. The American Diabetes Association recommends 30 minutes of moderate-to-vigorous intensity aerobic exercise at least 5 days a week, and varying the types of exercise can help. Mike’s workout plan often includes walking his dogs and going to a fitness class with running, rowing, and strength exercises.
• Lean on your support team to stay motivated. As the sun begins to set on the day, Mike enjoys relaxing with his family. Part of his diabetes management plan includes recruiting people like his family members to be his teammates, and talking with his doctor like he’s his head coach. After a busy day, Mike and his wife, Chris, team up to cook a healthy dinner together. Chris helps Mike plan ahead and stay motivated to stick to the game plan that Mike and his doctor set.
• Feel confident in your numbers. To help Mike manage his type 2 diabetes, Mike’s doctor prescribes INVOKANA^® (canagliflozin). INVOKANA^® is taken by over 1.5 million people since launch and counting to help lower their A1C numbers. Mike sees lowering his A1C numbers as a goal and a challenge, and says when he wants to improve, “I physically put my numbers somewhere, look at them, and say ‘Next time, this is going to be better!’” INVOKANA^® helps Mike feel confident about his numbers and taking it as prescribed is an important part of the game plan he created with his doctor.

INVOKANA^® is a once-daily pill used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. In most clinical trials, the majority of people taking INVOKANA^® reached an A1C goal of less than 7.0 percent, which is recommended by the American Diabetes Association. INVOKANA^® is not for weight loss, but may help people lose weight — on average 2-3 percent. INVOKANA^® was also shown in clinical trials to reduce systolic blood pressure (on average 3-5 mmHg), though it is not indicated as a blood pressure medication. Results may vary by dose and when used alone or with certain other diabetes medications. INVOKANA^® may increase a person’s risk of lower-limb amputations. The most common side effects of INVOKANA^® include genital yeast infections, urinary tract infection, and changes in urination. These specific adverse events were generally mild to moderate in intensity in clinical studies.

If you’re looking for ways to manage your own type 2 diabetes and feel confident in your numbers, visit INVOKANA.com for planning and motivation tips. Find “secrets to staying active” and browse diabetes-friendly recipes with detailed preparation directions, ingredient tips, and nutrition facts to help ensure you’re eating well. Be sure to talk to your doctor about managing your diabetes and before starting a diet or exercise program.

WHAT IS INVOKANA^®?

INVOKANA^® is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. INVOKANA^® is not for people with type 1 diabetes or with diabetic ketoacidosis (increased ketones in blood or urine). It is not known if INVOKANA^® is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

INVOKANA^® can cause important side effects, including:

• Amputations. INVOKANA^® may increase your risk of lower-limb amputations. Amputations mainly involve removal of the toe or part of the foot; however, amputations involving the leg, below and above the knee, have also occurred. Some people had more than one amputation, some on both sides of the body. You may be at a higher risk of lower-limb amputation if you: have a history of amputation, have heart disease or are at risk for heart disease, have had blocked or narrowed blood vessels (usually in leg), have damage to the nerves (neuropathy) in the leg, or have had diabetic foot ulcers or sores. Call your doctor right away if you have new pain or tenderness, any sores, ulcers, or infections in your leg or foot. Your doctor may decide to stop your INVOKANA^® for a while if you have any of these signs or symptoms. Talk to your doctor about proper foot care
• Dehydration. INVOKANA^® can cause some people to become dehydrated (the loss of too much body water), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at higher risk of dehydration if you have low blood pressure, take medicines to lower your blood pressure (including diuretics [water pills]), are on a low sodium (salt) diet, have kidney problems, or are 65 years of age or older
• Vaginal yeast infection. Women who take INVOKANA^® may get vaginal yeast infections. Symptoms include: vaginal odor, white or yellowish vaginal discharge (discharge may be lumpy or look like cottage cheese), or vaginal itching
• Yeast infection of the penis (balanitis or balanoposthitis). Men who take INVOKANA^® may get a yeast infection of the skin around the penis. Symptoms include: redness, itching, or swelling of the penis; rash of the penis; foul-smelling discharge from the penis; or pain in the skin around penis

Talk to your doctor about what to do if you get symptoms of a yeast infection of the vagina or penis.

Do not take INVOKANA^® if you:

• are allergic to canagliflozin or any of the ingredients in INVOKANA^®. Symptoms of allergic reaction may include: rash; raised red patches on your skin (hives); or swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing
• have severe kidney problems or are on dialysis

Before you take INVOKANA^®, tell your doctor if you have a history of amputation; heart disease or are at risk for heart disease; blocked or narrowed blood vessels (usually in leg); damage to the nerves (neuropathy) of your leg; diabetic foot ulcers or sores; kidney problems; liver problems; history of urinary tract infections or problems with urination; are on a low sodium (salt) diet; are going to have surgery; are eating less due to illness, surgery, or change in diet; pancreas problems; drink alcohol very often (or drink a lot of alcohol in short-term); ever had an allergic reaction to INVOKANA^®; or have other medical conditions.

Tell your doctor if you are or plan to become pregnant, are breastfeeding, or plan to breastfeed. INVOKANA^® may harm your unborn baby. If you become pregnant while taking INVOKANA®, tell your doctor right away. INVOKANA^® may pass into your breast milk and may harm your baby. Do not breastfeed while taking INVOKANA^®.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take diuretics (water pills), rifampin (used to treat or prevent tuberculosis), phenytoin or phenobarbital (used to control seizures), ritonavir (Norvir^®, Kaletra^® – used to treat HIV infection), or digoxin (Lanoxin^® – used to treat heart problems).

Possible Side Effects of INVOKANA^®

INVOKANA^® may cause serious side effects, including:

• Ketoacidosis (increased ketones in your blood or urine). Ketoacidosis has happened in people who have type 1 or type 2 diabetes, during treatment with INVOKANA^®. Ketoacidosis is a serious condition, which may need to be treated in a hospital. Ketoacidosis may lead to death. Ketoacidosis can happen with INVOKANA^® even if your blood sugar is less than 250 mg/dL. Stop taking INVOKANA^® and call your doctor right away if you get any of the following symptoms: nausea, vomiting, stomach-area pain, tiredness, or trouble breathing
• Kidney problems. Sudden kidney injury has happened to people taking INVOKANA^®. Talk to your doctor right away if you: 1) reduce the amount of food or liquid you drink, if you are sick, or cannot eat or 2) you start to lose liquids from your body from vomiting, diarrhea, or being in the sun too long
• A high amount of potassium in your blood (hyperkalemia)
• Serious Urinary Tract Infections: may lead to hospitalization and have happened in people taking INVOKANA^®. Tell your doctor if you have signs or symptoms of a urinary tract infection such as: burning feeling while urinating, need to urinate often or right away, pain in the lower part of your stomach (pelvis), or blood in the urine. Some people may also have high fever, back pain, nausea, or vomiting
• Low blood sugar (hypoglycemia). If you take INVOKANA^® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you take INVOKANA^®

Signs and symptoms of low blood sugar may include: headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking, or feeling jittery.

Serious allergic reaction. If you have any symptoms of a serious allergic reaction, stop taking INVOKANA^® and call your doctor right away or go to the nearest hospital emergency room.

Broken Bones (fractures): Bone fractures have been seen in patients taking INVOKANA^®. Talk to your doctor about factors that may increase your risk of bone fracture.

The most common side effects of INVOKANA^® include: vaginal yeast infections and yeast infections of the penis; changes in urination, including urgent need to urinate more often, in larger amounts, or at night.

Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Janssen Scientific Affairs, LLC at 1-800-526-7736.

Please see full Product Information, including Boxed Warning, and Medication Guide for INVOKANA^®.

Canagliflozin is licensed from Mitsubishi Tanabe Pharma Corporation. Trademarks are those of their respective owners.

076190-171006

2018-04-03T15:01:00

(BPT) – It’s not just you. Losing weight is a tough thing to pull off! Forty-one percent of us are currently trying to do it, yet only approximately three in 10 are confident we’ll succeed, according to a new national online survey, “The Truth About Weight Loss”, conducted by The Harris Poll on behalf of Zaluvida, makers of I-REMOVE^®.

Problem is, the survey also suggests today’s lifestyle might be a major obstacle to reaching and maintaining our weight-loss goals. Long work hours, commutes, errands, and kids’ activities all make it hard to plan and prepare healthy dinners, let alone fit in daily high-impact cardio sessions at the gym. And those sessions may be more needed than ever — the vast majority of health care professionals who were surveyed say that screen time[i] and the use of on-demand services[ii] prevent Americans from being more active. At least 77 percent of health care professionals who participated say losing weight is more difficult today than it was for previous generations because of Americans’ busy, modern lifestyles[iii].

How do you get around the many demands of your daily life and lose weight anyway? Here are a few tips to get you on your way to shedding unwanted pounds, even with your busy lifestyle.

1. Start small, start simple.

A healthy new outlook is great, but don’t get crazy: If you’re piling on too many major changes at once, they may be less likely to stick. A successful weight loss plan is one that you can stick to long term[iv], isn’t time consuming[v], and doesn’t disrupt your daily routine[vi], according to most of the health care providers surveyed. For starters, think in terms of making small, incremental changes to trade unhealthy habits for better ones.

2. Steer clear of crash diets.

Sure, there are all kinds of diets and other gimmicky plans out there that make big promises to zap those pounds in a matter of days. In reality, anything that relies on extremely low calorie intake is not only bad for your health, it can backfire. Extreme diets that include drastic calorie reduction can lead to increased fatigue, according to health care professionals who were surveyed[vii]; they also say you may end up gaining weight in the end because your body enters “starvation mode” to protect its resources[viii].

3. Consider new options.

When it comes to weight loss, the struggle is real — especially today. Luckily, health care providers get that. The majority agrees that weight loss would be easier for their patients if there were a weight-loss product or aid that fits into their patients’ lifestyles without unpleasant side effects[ix]. One such product is I-REMOVE[x], the No. 1-selling weight-loss formula in Europe, which is now newly available in the U.S. at Walgreens and other retailers. Clinically tested to help people lose weight and maintain weight loss without undesirable side effects, it is shown to deliver up to three times more weight loss vs. dieting alone.

I-REMOVE can be easily incorporated into a busy schedule, but must be part of a healthy lifestyle, which includes eating healthier and moving more. This doesn’t mean making drastic changes or spending hours in the gym, it means making better eating decisions — even if the occasional slip-up happens — and incorporating more movement into a typical day.

How it works: Take it after a meal, and during digestion, it binds with up to 28 percent of the fat content, transforming it into fat-fiber complexes that pass gently through the body — without unpleasant side effects. It has also been shown to promote a pleasant feeling of fullness.

4. Find your weight-loss expert.

The guidance of a health care professional is invaluable when you’re trying to achieve weight loss in a safe, healthy, and sustainable way. Yet, only 32 percent of adults who are currently trying or have ever tried to shed pounds have talked to a health care provider for help with a plan. Your health care provider can tell you what’s right for your age, fitness level and health goals. Plus, by talking openly with your health care provider about your weight-loss goals and personal challenges, you may get useful tips about how to make healthy choices that can work with your particular lifestyle and situation.

5. Treat yourself!

When you do shed inches and pounds, make a point to celebrate! Buy that new outfit that shows off your new form, and post your results on social media so you can bask in the many rounds of virtual high-fives from your friends and family. These celebrations will lift your spirits and motivate you to keep you going!

For more results on ‘The Truth about Weight Loss’ survey, visit www.weightlossfindings.com. For more information about I-REMOVE, visit www.i-remove.com.

[i] 95% PCPs, 97% pharmacists

[ii] 82% PCPs, 84% pharmacists

[iii] 77% of PCPs, 81% of pharmacists

[iv] 79% of PCPs, 69% of pharmacists

[v] 56% of PCPs, 55% of pharmacists

[vi] 54% of PCPs, 53% of pharmacists

[vii] 78% of PCPs, 86% of pharmacists

[viii] 77% of PCPs, 84% of pharmacists

[ix] 63% of PCPs, 60% of pharmacists

[x] I-REMOVE has been demonstrated to effectively boost weight-loss efforts in people 18 years of age and older who are overweight or slightly obese.

Editor’s Note:

About the National Survey: ‘The Truth about Weight Loss’ survey was conducted online within the United States by The Harris Poll on behalf of Zaluvida, the makers of I-REMOVE^®, between October 13 and November 6, 2017. The consumer arm of the survey included a total of 1,005 U.S. adults ages 18+, of whom, 713 are currently trying (n=429) or have ever tried (n=284) to lose weight. The professional arm of the survey included 961 U.S. adults ages 18+ who are primary care physicians (n=458) or pharmacists (n=503). For complete research method, including weighting variables and subgroup sample sizes, please contact press@i-remove.com.

2018-04-03T14:01:00

(BPT) – If you’ve ever tried to lose weight, you probably know it can seem like an overwhelming task. In fact, a recent survey conducted by The Harris Poll indicates losing weight is harder than ever before, and that today’s busy modern lifestyle is a key reason why.

But, don’t lose hope. Results also suggest that taking a new approach to weight loss can help, and that you can increase your chances for reaching and maintaining your weight-loss goals by getting a clear picture of the factors holding you back, and establishing a plan compatible with your lifestyle.

“The Truth About Weight Loss” survey was conducted online by The Harris Poll in October/November 2017 on behalf of Zaluvida, the makers of I-REMOVE (R), and included nearly 1,000 health care professionals [458 primary care physicians (PCPs) and 503 pharmacists], and more than 1,000 U.S. adults ages 18 and over.

So, what are our roadblocks?

The survey paints a picture of U.S. adults who are discouraged when it comes to weight loss, and some of the key reasons why.

Among its findings:

* 77 percent of PCPs and 81 percent of pharmacists say losing weight is harder today than it was for previous generations because of the busy, modern lifestyle of Americans.

* Too much screen time (i.e., time spent on computers, tablets and mobile phones) has resulted in Americans leading less-active lifestyles, according to 95 percent of PCPs and 97 percent of pharmacists.

* Lack of time is taking a toll as well. 97 percent to 98 percent of PCPs and pharmacists are concerned that Americans not taking time to plan healthy meals will negatively impact their weight and their family’s weight.

The result of all this? Widespread frustration. While 41 percent of Americans are now attempting to lose weight, only 29 percent of them are confident they’ll achieve their current weight-loss goals. Fifty-nine percent of them say they’re frustrated by previous attempts to lose weight — typically, they’ve tried to slim down a substantial five times in the past five years.

What’s needed? A sustainable plan, and more weight-loss options.

At least 89 percent of health care professionals surveyed say Americans need to take a new approach to weight loss that fits with today’s modern lifestyle.

Instead of embarking blindly on a goal to lose weight, they say people should develop a plan that accounts for their potential stumbling blocks — most advise that your plan should be sustainable (79 percent of PCPs and 69 percent of pharmacists), not be time-consuming (56 percent of PCPs and 55 percent of pharmacists), and not require sudden or major shifts to your daily routine (54 percent of PCPs and 53 percent of pharmacists).

You may also want to consider new options; at least 84 percent of PCPs and pharmacists say they wish they had more weight-loss options for people who are overweight but not yet obese, and 63 percent of PCPs and 60 percent of pharmacists agree that a weight-loss product/aid that fits into one’s lifestyle without unpleasant side effects would make it easier for their patients to lose weight.

One such product that’s now available in the U.S. is I-REMOVE, a weight-loss aid aimed at helping people lose weight and achieve healthier lifestyles they can sustain long-term. As the No. 1 best-selling weight-loss formula in Europe, I-REMOVE is clinically tested and shown to help with weight loss and maintenance, and can deliver up to three times the weight loss of dieting alone. Sold in the U.S. it is available nationwide at Walgreens and other retailers.

Consult with your health care professional before embarking on any weight-loss plan.

For more survey results, visit www.weightlossfindings.com.

For more information about I-REMOVE, visit https://www.i-remove.com.

About the National Survey “The Truth about Weight Loss”

The survey was conducted online within the United States by The Harris Poll on behalf of Zaluvida between October 13 and November 6, 2017. The consumer arm of the survey included a total of 1,005 U.S. adults ages 18+, of whom, 713 are currently trying (n=429) or have ever tried (n=284) to lose weight. The professional arm of the survey included 961 U.S. adults ages 18+ who are primary care physicians (n=458) or pharmacists (n=503). For complete research method, including weighting variables and subgroup sample sizes, please contact press@i-remove.com.

2018-04-03T10:35:00

(BPT) – Major life events like childbirth, aging and menopause can cause unwanted changes to a woman’s body. These tend to include a woman’s overall vaginal health that can impact her daily life in terms of work, travel, sports and also, her sex life.

Fortunately, there is an innovative, non-surgical treatment that can restore confidence by helping women of all ages feel more like their younger, more vital and sensual selves. This non-invasive procedure reverses the changes in vaginal tissue that are often associated with aging, childbirth and menopause. With the Juliet^™ laser, women can feel and see improvement after every treatment as the vagina is restored to a more youthful state.

Bay Area medical device company, CUTERA^®, recently launched the Juliet^™ laser, an innovative system that provides women renewed confidence, quality of life and enhanced sexual function. This quick, painless treatment is performed in your provider’s office and takes approximately 15 minutes and can be performed without anesthesia, incisions or downtime. The Juliet laser works by delivering two passes of laser energy to the vaginal area. The first pass stimulates the remodeling of collagen while the second pass stimulates the damaged tissue. As a result, women experience an overall improvement in vaginal rejuvenation.

“Today’s woman strives to both look and feel good, and their sexuality is an important part of their lives,” reports Dr. James Mirabile, a Board-Certified Gynecologist in Overland Park, Kansas. “The Juliet laser is turning back the clock on feminine aging. Some women are even showing improvement in symptoms after a single treatment with best results achieved after two to three sessions. Lubrication, vaginal laxity and tone can be vastly improved. Sex becomes comfortable again as Juliet treats burning, itching, dryness and painful intercourse, with results continuing to improve in the months that follow. It is the treatment of choice for women experiencing menopause to help restore their self-confidence. Our patients tolerate the procedure very well and are extremely pleased with the results we can achieve,” he said.

According to Dr. Samuel Lederman, Co-Director of Laser Skin & Wellness in Palm Beach County, Florida, “With the Juliet laser, we have found that dramatic improvements can occur in quality of life and our patients are genuinely excited about the results. Women who have had two or three children are amazed by the changes they experience. Post-menopausal women are delighted with the reduction in the symptoms of feminine aging that can be achieved with this revolutionary in-office procedure. Because Juliet’s beneficial effects continue to improve over time, many women report further clinical benefits in three or more months after they have been treated,” he said.

The Juliet laser is a safe and effective treatment for many of the symptoms typically associated with diminished estrogen production from aging, changes after childbirth, as well as after breast cancer treatments or hysterectomy.

To find a Juliet provider near you, visit the Cutera Treatment Finder.