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6 expert tips to off-road like a pro

2021-05-18T15:01:01

(BPT) – Nothing looks more fun than the freedom of driving off-road, with the exhilaration of exploring the great outdoors and getting away on your own terms. But off-roading in real life is not like in movies and video games. Keeping that sense of fun and excitement is still possible while not endangering yourself — or damaging your vehicle or your surroundings.

To explore the world of off-roading, here are tips to help you stay safe — and have a great experience.

1. Start with the right equipment

Choosing the right tire is a crucial part of preparing your vehicle for off-roading. Don’t be fooled into thinking the tougher-looking mud-terrain tire is always the better option — the tire’s ability to perform should always outweigh its aesthetics.

Knowing both your driving style and the types of terrain you’ll likely encounter are key to making a well-informed decision. Do your research, ask questions and be realistic about what you need from your tires.

2. Know your vehicle

One of the most important ways to prepare for the rigors of recreational off-roading is to know your vehicle, inside and out. A great way to start is by attending a local off-road driving course to learn the inner workings of a 4×4 vehicle, plus get expert-guided instruction on how your vehicle performs off the pavement.

In the world of four-wheeling, knowledge is power. Another good place to find that knowledge is by actually reading your owner’s manual.

3. Understand how to read and ride the terrain

Successful and safe off-roading means being alert to your surroundings while you’re out there, and preparing for that environment before your trip. Research the location before heading out so you’ll know what conditions to expect.

Sand, snow and mud

  • Deflate your tires a bit to increase your tire footprint for better traction.
  • Use steady momentum all the way through.
  • In sand and snow, if your wheels start to spin, ease off the gas a little to let the tires slow down and regain traction.
  • In mud, maintain some wheel spin to help clear mud from the drive tire.

Rocks, logs and ditches

  • Approach obstacles at an angle so only one tire engages, leaving the other three tires on solid ground for traction.
  • To protect the fragile components on the underside of your vehicle, it’s best to drive over an obstacle by placing one tire on it, then gently driving over it.

Hills

  • Approach the hill straight on, so the weight is distributed equally, providing equal traction to all four tires.
  • Use as high a gear as the vehicle will handle comfortably on the hill. If the gear is too low, you will spin the tires. If it’s too high, you won’t have enough power.
  • Always prepare for a failed climb and have an escape plan.

4. Have a recovery plan for sticky situations

Safety is the highest priority for any recovery situation where your vehicle is immobilized. Even professional off-roaders find themselves in these positions, but with a recovery plan, you can safely avoid a potentially dangerous situation.

The Strap and Rope Recovery is a method professional off-roaders use to free their vehicle using Recovery Straps and Kinetic Recovery Rope. You’ll connect the rope to your immobilized vehicle and to another vehicle to pull it out. For reference, you’ll want to make sure both vehicles are lined up. Then, the other vehicle pulls forward to slowly free your vehicle.

Always pack these recovery tools to free your vehicle if needed:

  • Hi-lift jack
  • Recovery boards
  • Bottle jack
  • Ground anchor

5. Respect the environment

Preserving trails for other riders, wildlife and future generations is the responsibility of every off-roader. Follow the T.R.E.A.D principles to ensure you’re doing your part to protect the environment, including:

  • Staying on designated trails
  • Disposing of waste
  • Respecting wildlife
  • Educating yourself about park rules and policies

6. Maximize your off-road experience

Take your off-road experience to the next level with the new BFGoodrich OnTrail app, available for iPhone and Android. The app allows users to find, record and navigate trails, share and connect with other off-roading community members, earn recognition and rewards, plus advance skillsets with easy-to-access tips and resources.

For more information on off-roading equipment, tips and tricks, visit www.BFGoodrich.com.

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5 fun – and delicious – ways to boost your wellness routine

2021-05-18T07:53:01

(BPT) – Want to revamp your wellness routine, but don’t know where to start? You may think adopting a healthier lifestyle means only discipline and deprivation, but in fact it’s more likely you’ll maintain a new wellness regimen if you create healthy habits you actually enjoy.

Here are five simple ways to support your well-being that are tasty, fun and easy to implement, so you’ll stay on that wellness journey for years to come.

1. Harness the power of organic fruits and veggies

You probably know that fruits and vegetables are good for you, and that they taste their best when freshly picked from your backyard, farmer’s market or another organic source. A convenient and tasty way to harness the power of organic fruit is taking Garden Of Life mykind Organics Apple Cider Vinegar Gummies — available at The Vitamin Shoppe and Super Supplements stores, and on vitaminshoppe.com. Made from organic apple cider, lemon juice, strawberries, raspberries, blueberries, tart cherries, elderberries and cranberries, these tasty gummies provide energy-boosting nutrients like vitamin B12.

One big fan of these supplements is health advocate and co-creator of mykind Organics, actress Alicia Silverstone.

“I wanted to make these gummies special, the way I like to do everything with mykind Organics, in the most natural and healthy way,” said Alicia Silverstone. “From the moment you see our label, to the first taste of deliciousness, through the way you feel when you take them, you can see they are made differently, from the highest quality, most nourishing ingredients available. That is truly what makes us different and sets us apart.”

Plus, these gummies allow you to incorporate apple cider vinegar into your wellness routine without the bitter taste.

2. Take mini movement breaks to support weight loss goals

Many of us are still working from home and sitting all day can take a toll on your health and energy levels, while also sabotaging your wellness goals. Try incorporating 5- to 10-minute mini “movement breaks” every hour or so into your daily schedule to help you increase your heart rate, energize your breathing and burn some calories. You can:

  • Take a brief walk
  • Dance to upbeat music
  • Do lunges, jumping jacks or pushups

Don’t forget to always consult your healthcare practitioner before beginning an exercise program.

For more help achieving your weight loss goals, taking just three Garden Of Life mykind Organics Apple Cider Vinegar Diet Gummies a day can help make your diet and exercise routine more effective with its Organic Svetol Green Coffee Bean Extract, which is clinically shown to burn fat and help maintain healthy blood glucose levels.

3. Enjoy some sunshine

As it’s starting to get nicer out every day, try spending some of your breaks outside, even if it’s just for 15 minutes to enjoy the sunshine. Vitamin D from the sun, fresh air and movement all help to uplift your mood and relieve tension.

4. Drink enough water

Energy lagging? Don’t reach for sugary drinks or snacks for an artificial jolt of energy that will likely have you crashing later. Instead, reach for some water! When we start to feel fatigued, it’s often a sign that our bodies are lacking the proper amount of water.

Along with making sure you’re drinking enough water throughout the day, try Garden Of Life mykind Organics Apple Cider Vinegar Energy Gummies with vitamin B12, organic green tea extract and organic coffeeberry whole coffee fruit extract to boost your energy and sharpen your focus.

5. Stretch for success

Stress-busting techniques like stretching and mindfulness not only help you cope with stress, but according to the Cleveland Clinic, can help strengthen your immune system. Stretch gently while breathing deeply periodically throughout the day to help relieve tension.

To further support your immune system, Garden Of Life mykind Organics Apple Cider Vinegar Probiotic Gummies have been shown to improve digestive health and provide immune support with their two billion colony-forming units (CFU) of clinically studied probiotics.

These organic, Non-GMO Project Verified and Certified Vegan gummies are a convenient and tasty way to enjoy all the benefits you love from organic apple cider vinegar, while supporting your digestive and immune health, burning fat and boosting energy.

Find all these delicious apple cider vinegar gummies and more at your local The Vitamin Shoppe and Super Supplements stores and online at vitaminshoppe.com, the leading destination for lifelong wellness solutions.

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The dramatic impact of light on health, mood, focus and more

2021-05-17T11:25:00

(BPT) – The sun goes up; the sun goes down. When it’s too dark, you flip on a switch. When it’s time for bed, you turn it off. Most people don’t put much thought into the role that light plays in their life, thinking of it in a solely functional manner. However, research shows that the benefits of light — particularly natural light — go far beyond facilitating sight. When used correctly, it can help improve focus, productivity, sleep and health.

The profound benefits of light

Light has a significant effect on biological functions and is central to well-being. For example, exposure to daylight affects sleep quality, efficiency, alertness, mood and growth. Conversely, lack of natural light can have the opposite impact and contribute to sluggishness, sadness, irritability, fatigue and lack of focus. Some medical conditions result from limited light exposure: seasonal affective disorder (SAD) and acute myocardial infarction (AMI) are two examples, occurring more frequently during the darker months of the year.

Modern humans spend most of their time indoors, but solving these issues isn’t as easy as turning on the light in a room because not all types of lights are equal. Dynamic lighting that mimics natural light is one of the best ways to get the benefits of natural light when inside and can be helpful in a variety of spaces, from the home and the office to fitness and health centers.

Independent studies have shown that dynamic lighting has many possible applications. For example, dynamic lighting has been used to help premature babies go home faster and professional hockey teams have gained a range of performance advantages in training, game preparation and recovery. Now dynamic lighting is being used to help people in their homes and where they work.

The development of personalized lighting systems

Being inside the majority of the day and often in front of screens inhibits the body’s natural ability to synchronize with sunlight. The desire to solve this problem by harnessing the potential of dynamic lighting led illumination technology company BrainLit® to develop BioCentric Lighting™.

“Natural variation of light is essential for humans and this need hasn’t changed despite our changed behaviors of spending more time indoors,” said BrainLit CEO Niclas M. Olsson. “BioCentric Lighting is the only system currently available that can fully promote the circadian alignment by synchronizing our biological needs with solar time through personalized lighting.”

How does this personalized daylighting system work?

“BioCentric Lighting is a smart lighting system based on the latest scientific knowledge of human anatomy and our personal response to light,” explained Olsson. “It is a self-learning system that integrates LED luminaires, sensors, Internet of Things (IoT) controls, artificial intelligence and cloud computing to simulate the biological benefits of the sun.”

A specific example is the BrainLit Alven™ light that can be used at home or in commercial settings. Each luminaire has a wide range specification to be able to expose people to healthy light. These luminaires are controlled and adjusted by the light controller, which sends control signals to all luminaires based on algorithms and related data gathered from the sensors in the environment. This unique patented system uses feedback to personalize lighting for optimum benefits that include:

Improved sleep: Light is a key factor in humans’ circadian rhythm, which is the sleep/wake cycle. A disrupted circadian rhythm can cause poor sleep and even some sleep disorders. BrainLit’s BioCentric Lighting System helps balance circadian rhythms to help you sleep well and feel more rested when you wake.

Improved productivity: BrainLit’s BioCentric Lighting System contributes to the balancing level and timing and production of the activation hormone cortisol and the sleep hormone melatonin. This helps contribute to better sleep when it’s time to rest and higher alertness when it’s time to be awake.

Alertness and focus: Daylight has an alerting effect on the brain. BrainLit’s BioCentric Lighting System stimulates the natural production of the activation hormone cortisol during the day by mimicking variations of daylight indoors, improving cognition, drive and creativity.

Immune support: Mimicking daylight indoors benefits many physiological processes vital to good health, including the immune system, metabolism, blood pressure, heart rate and body temperature.

“BioCentric Lighting can be personalized based on specific needs, making it useful for so many different situations,” said Olsson. “It can be used at training centers to help athletes thrive. It can be used at manufacturing plants to help night-shift workers stay alert. It can be used in health care centers to help patients recover. The possibilities are virtually endless.”

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One woman’s story of dealing with bipolar disorder and uncontrolled movement symptoms

2021-05-17T08:01:00

(BPT) – Carol Conn’s bipolar disorder went undiagnosed for 10 years, and it wasn’t until she was in her mid-40s that she experienced a psychotic episode and was admitted into the hospital.[i] “I was imagining all sorts of crazy things,” she said. “I thought a friend of mine was watching me by satellite.” One of Carol’s sisters and a friend were able to intervene, and after a 10-day stay in the hospital, she was finally diagnosed with bipolar disorder and prescribed an antipsychotic treatment to manage her bipolar symptoms.

Six months after starting her medication, one of Carol’s friends told her that she was noticing some uncontrollable movements in Carol’s face. Carol didn’t notice at first, but soon started to experience what she described as “tension in her jaw that felt like pulling.”

Carol didn’t know it yet, but she was starting to experience symptoms of tardive dyskinesia (TD). TD is associated with certain prescription medications used to treat mental health or gastrointestinal conditions. It can appear as mild to severe twitching, shaking or jerking in the hands, feet, face or torso. One in four people taking certain mental health medications may develop TD.[ii],[iii]

Carol was embarrassed, and as much as she wanted to avoid other people because of her TD, she still had to go to work every day. There was no way to hide what was happening. Not only was she noticing her TD symptoms, but those close to her also started to point out her uncontrollable movements. “It’s hard to tell people that it’s a side effect of medication because you don’t want to reveal to everyone that you have a mental health issue,” said Carol.

Whether symptoms are mild, moderate or severe, the impact of TD can be significant, causing physical changes that may lead to functional and emotional changes. The symptoms of TD may also impact social well-being, such as avoiding social interactions because of uncontrollable movements.[iv]

Eventually, Carol began seeing a new psychiatrist. During her first visit, the doctor noticed Carol’s TD symptoms right away and was able to officially diagnose her. “It was shocking and embarrassing that my TD was so obvious,” said Carol.

Mental health disorders, such as bipolar, can be challenging to treat. Symptoms of bipolar disorder can be complex, and not everyone experiences the same symptoms in the same way. That’s why it can take years for clinicians to find the right combination of treatments.[v] Once the right combination of treatments is established, many patients choose to cope with any side effects they experience, like TD, rather than alter their treatment regimen to address them and risk relapse.[vi]

Carol’s doctor told her about a treatment that could help manage her TD symptoms, called AUSTEDO® (deutetrabenazine) tablets. AUSTEDO treats the involuntary movements of TD in adults while allowing people to continue with some of their mental health medications like antipsychotics or antidepressants.[vii]

AUSTEDO® is a prescription medicine that is used to treat:

  • movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if AUSTEDO® is safe and effective in children.

Important Safety Information

AUSTEDO can cause serious side effects in people with Huntington’s Disease, including: depression, suicidal thoughts, or suicidal actions.

Do not start taking AUSTEDO if you are depressed (have untreated depression or depression that is not well controlled by medicine) or have suicidal thoughts. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts or feelings. This is especially important when AUSTEDO is started and when the dose is changed. Call your healthcare provider right away if you become depressed, have unusual changes in mood or behavior, or have thoughts of suicide.

Please see additional Important Safety Information below and full Prescribing Information, including Boxed Warning.

Carol was thrilled to know there was a treatment for tardive dyskinesia and started taking the medicine as soon as it was available. After she began treatment for her uncontrollable movements, Carol’s friends noticed an improvement. Carol stated that she doesn’t feel the “need to be as self-conscious of her TD” anymore.

Before starting AUSTEDO, Carol’s doctor talked to her about possible serious side effects that she might experience, such as suicidal thoughts, suicidal actions and depression. Additionally, AUSTEDO is not indicated to treat emotional distress resulting from uncontrolled movements.

For Carol, the hardest part about having bipolar and TD was feeling ashamed, and like she had somehow caused it. Unfortunately, Carol’s feelings aren’t unique. Many people living with a mental health conditions feel stigmatized and delay seeking treatment due to concerns about being treated differently.[viii]

This month is Mental Health Awareness Month and Tardive Dyskinesia Awareness Week, a time dedicated to fighting stigma, providing support and educating the public on mental illness so people living with mental health conditions, like Carol, can feel more comfortable speaking out about how they’re feeling and finding treatment, when necessary.[ix] Today, Carol’s TD symptoms have improved, and she encourages anyone struggling with mental health issues or tardive dyskinesia to speak to their doctor right away to see if AUSTEDO may be appropriate for them.

If you or a loved one are struggling with TD, ask your doctor about AUSTEDO, as it may help you manage TD while you continue with your mental health medications. Visit AUSTEDO.com/tardive-dyskinesia to learn more about a potential treatment option.

IMPORTANT SAFETY INFORMATION (Continued)

Do not take AUSTEDO if you:

  • have Huntington’s disease and are depressed or have thoughts of suicide.
  • have liver problems.
  • are taking a monoamine oxidase inhibitor (MAOI) medicine. Do not take an MAOI within 14 days after you stop taking AUSTEDO. Do not start AUSTEDO® if you stopped taking an MAOI in the last 14 days. Ask your healthcare provider or pharmacist if you are not sure.
  • are taking reserpine. Do not take medicines that contain reserpine (such as Serpalan® and Renese®-R) with AUSTEDO. If your healthcare provider plans to switch you from taking reserpine to AUSTEDO, you must wait at least 20 days after your last dose of reserpine before you start taking AUSTEDO.
  • are taking tetrabenazine (Xenazine®). If your healthcare provider plans to switch you from tetrabenazine (Xenazine®) to AUSTEDO, take your first dose of AUSTEDO on the day after your last dose of tetrabenazine (Xenazine®).
  • are taking valbenazine (Ingrezza®).

Other possible serious side effects include:

  • Irregular heartbeat (QT prolongation). AUSTEDO increases your chance of having certain changes in the electrical activity in your heart. These changes can lead to a dangerous abnormal heartbeat. Taking AUSTEDO with certain medicines may increase this chance.
  • Neuroleptic Malignant Syndrome. Call your healthcare provider right away and go to the nearest emergency room if you develop these signs and symptoms that do not have another obvious cause: high fever, stiff muscles, problems thinking, very fast or uneven heartbeat, or increased sweating.
  • Restlessness. You may get a condition where you feel a strong urge to move. This is called akathisia.
  • Parkinsonism. Symptoms include: slight shaking, body stiffness, trouble moving, trouble keeping your balance, or falls.

Sleepiness (sedation) is a common side effect of AUSTEDO. While taking AUSTEDO, do not drive a car or operate dangerous machinery until you know how AUSTEDO affects you. Drinking alcohol and taking other drugs that may also cause sleepiness while you are taking AUSTEDO may increase any sleepiness caused by AUSTEDO.

The most common side effects of AUSTEDO in people with Huntington’s disease include sleepiness (sedation), diarrhea, tiredness, and dry mouth.

The most common side effects of AUSTEDO in people with tardive dyskinesia include inflammation of the nose and throat (nasopharyngitis) and problems sleeping (insomnia).

These are not all the possible side effects of AUSTEDO. Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the accompanying Medication Guide.

Please see full Prescribing Information, including Boxed Warning.

[i] Goldberg J MD. Web MD. Psychosis and Psychotic Episodes. WedMD website. Accessed March 2021. https://www.webmd.com/schizophrenia/guide/what-is-psychosis.

[ii] National Alliance on Mental Illness (NAMI). Tardive Dyskinesia. NAMI website. Accessed March 2021. https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Tardive-Dyskinesia.

[iii] Waln O, Jankovic J. An Update on Tardive Dyskinesia: From Phenomenology to Treatment. Tremor Other Hyperkinet Mov. 2013;3:1-11. Accessed March 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709416/pdf/tre-03-161-4138-1.pdf.

[iv] Strassnig M, et al. CNS Spectr. 2017:1-8. 7. Carbon M, et al. J Clin Psychiatry. 2017;78(3):e264-e278. Accessed March 2021. https://www.cambridge.org/core/journals/cns-spectrums/article/abs/tardive-dyskinesia-motor-system-impairments-cognition-and-everyday-functioning/850905EE7069B81BE469D519F90B060D.

[v] Pary R MD, PR Matuschka PharmD, Lewis S ARNP PhD, et. al. Managing Bipolar Depression. Psychiatry. 2006; 3(2): 30-41. Accessed March 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990551/pdf/PE_3_2_30.pdf

[vi] International Bipolar Foundation. Finding the Right Medication. IBF website. Accessed March 2021. https://ibpf.org/articles/finding-the-right-medication/#:~:text=Be%20patient%20as%20it%20can,you%20find%20the%20right%20balance.

[vii] AUSTEDO® (deutetrabenazine) tablets current Prescribing Information. Parsippany, NJ. Teva Neuroscience, Inc.

[viii] American Psychiatric Association. Stigma, Prejudice and Discrimination Against People with Mental Illness. APA website. Accessed March 2021. https://www.psychiatry.org/patients-families/stigma-and-discrimination.

[ix] National Alliance on Mental Illness. Mental Health Month. NAMI website. Accessed March 2021. https://www.nami.org/Get-Involved/Awareness-Events/Mental-Health-Month.

April 2021
AUS-43384

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One nurse’s message to sickle cell disease patients during COVID-19: Get the care you need and deserve

2021-05-17T08:01:00

(BPT) – As a nurse practitioner traveling the country to help fill the ongoing nursing shortage, Lakesha Dickerson has had a front-row seat to the COVID-19 pandemic. But Dickerson has viewed the pandemic through another lens, too — she is a Black woman living with sickle cell disease (SCD).

When she was diagnosed with SCD, Dickerson was told she wouldn’t live past her 30s. SCD is a devastating inherited blood disorder that occurs in one out of every 365 African American births and impacts more than 100,000 people in the United States.[1] The lifelong inherited blood disorder occurs when red blood cells change shape, becoming rigid and deformed in a sickle, or crescent, shape. The cells become stiff and sticky, causing them to block blood flow and break down inside the blood vessels. The disease requires complex, multi-disciplinary care, but unfortunately many patients face significant challenges getting the care they need and deserve. Dickerson wants to change that.

“Since I was little, my experience with sickle cell disease has opened my eyes to the positive impact healthcare professionals can have on patients. On the other hand, it has also shown me the struggles and racial biases that people of color often face to get needed medical care,” she said.

COVID-19 has magnified the health disparities faced by the Black community, from discrimination and stigma to the lack of qualified providers. People living with SCD, called “warriors” because of the significant battles they fight, especially struggle to continue their care while navigating the deadly virus. People with SCD are among the populations most vulnerable to severe illness and death from COVID-19.[2]

Finding hope

Because of the challenges she faced, Dickerson decided at age 15 to become a nurse to help others on their own health journey. Meanwhile, her SCD symptoms only became more challenging as she grew older. But none of the available treatment methods seemed to help.

After speaking with her doctor, Dickerson learned about a clinical trial for people with SCD and was able to enroll in the study. She received, Oxbryta® (voxelotor) tablets, a prescription medicine used for the treatment of sickle cell disease in adults and children 12 years of age and older. It is the first approved medicine that specifically targets the sickling of red blood cells, or hemoglobin polymerization, which is the root cause of SCD.

It is not known if Oxbryta® is safe and effective in children below 12 years of age. This indication is approved under accelerated approval based on increase in hemoglobin (Hb). Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s). Please see Important Safety Information below. For additional information, visit Oxbryta.com.

Now Dickerson wants to empower others with SCD to get the care they need. “Take control of your health and speak to your doctor about available treatment options,” she said.

Confidence in the COVID-19 vaccine

Recently, Dickerson temporarily relocated to Texas to combat the country-wide nursing shortage, caused in part by the pandemic. After seeing, first-hand, the toll of COVID-19 on her patients, she wants to encourage others, especially her fellow SCD warriors, to get the COVID-19 vaccine when available.

“As a nurse attending to up to 12 patients at a time, I was terrified of the risks associated with COVID-19, and as an SCD patient, I was extremely anxious because of the increased danger I put myself in each day going to work,” she said. “Once vaccines were available, I regained hope, though I was initially skeptical, but I did my research and listened to the science, ultimately deciding that receiving the COVID-19 vaccine was the best decision for my family and me.

Dickerson hopes her journey will encourage other SCD patients to take precautions, including getting vaccinated. Even as more of the population receives the vaccine, it’s important for SCD patients to closely follow all CDC recommendations and continue to work with their care team to manage their SCD.

The last decade of SCD research has seen more progress than in the prior 50 years, and this offers hope to those suffering from SCD and their loved ones.

INDICATION

What is OXBRYTA?

OXBRYTA is a prescription medicine used for the treatment of sickle cell disease in adults and children 12 years of age and older.

It is not known if OXBRYTA is safe and effective in children below 12 years of age.

This indication is approved under accelerated approval based on increase in hemoglobin (Hb). Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trial(s).

IMPORTANT SAFETY INFORMATION

Do not take OXBRYTA if you have had an allergic reaction to voxelotor or any of the ingredients in OXBRYTA. See the end of the patient leaflet for a list of the ingredients in OXBRYTA.

If you are receiving exchange transfusions, talk to your healthcare provider about possible difficulties with the interpretation of certain blood tests when taking OXBRYTA.

Before taking OXBRYTA, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems
  • are pregnant or plan to become pregnant. It is not known if OXBRYTA can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if OXBRYTA can pass into your breastmilk and if it can harm your baby. Do not breastfeed during treatment with OXBRYTA and for at least 2 weeks after the last dose

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines may affect how OXBRYTA works. OXBRYTA may also affect how other medicines work.

What are the possible side effects of OXBRYTA?

OXBRYTA can cause serious side effects, including:

Serious allergic reactions. Tell your healthcare provider or get emergency medical help right away if you get:

  • rash
  • hives
  • shortness of breath
  • swelling of the face

The most common side effects of OXBRYTA include:

  • headache
  • diarrhea
  • stomach (abdominal) pain
  • nausea
  • tiredness
  • rash
  • fever

These are not all the possible side effects of OXBRYTA.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Global Blood Therapeutics at 1-833-428-4968 (1-833-GBT-4YOU).

Keep OXBRYTA and all medicines out of the reach of children.

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A simple guide to finding the best grill for you

2021-05-17T12:05:00

(BPT) – The sound of the sizzle, the smell of foods cooking outdoors, the undeniable taste — it’s time to get back to the barbecue. For many people, a grill becomes a second kitchen. For others, it’s their primary way of cooking all year long.

“We need it more than ever after a year like this,” says Steven Raichlen, grilling authority, author and host of television’s “Project Fire.” “Grilling brings joy. Unleashing your inner pyromaniac is fun. Building a fire is fun. Waltzing the food from hot spots to cool spots is fun. Grilling is an interactive sport. Every grill session is different and that alone makes it joyful.”

More than just cooking good food, Raichlen says grilling is a bonding activity that focuses on a simple pleasure that everyone enjoys.

“It’s fun and uncanny how grilling brings people together. No one gathers around the stove to watch a pot of stew simmer. Light your grill, people congregate and you, the grill master, become master of ceremonies,” he says.

The appeal of grilling transcends generations, and many people are now shopping for new grills so they can enjoy cooking outdoors. The problem is there are many types of grills, different sizes and varying price points, so it’s difficult to know which is right for your needs.

Saturday, May 29, is National Back to Barbecue Day, one of the busiest shopping days of the year for new grills. If you are looking to buy a new grill, the experts at the Hearth, Patio & Barbecue Association share some important things to keep in mind:

Types of grills to consider

Gas: For people who want convenience. Just like your kitchen stove, it can be ready to cook in 10 minutes, and it’s easy to regulate cooking temps.

Charcoal: For those who love being hands-on with the nuances of outdoor grilling. Some say charcoal provides the best flavor experience. Good for low and slow cooking and high heat searing.

Pellet: For people who want the most in flavor. Wood pellet grills are among the most energy efficient and burn clean. Pellets come in varieties such as hickory, mesquite and oak, providing a truly flavorful cooking experience.

Electric: For people who love simplicity. Electric grills are designed to produce constant heat and operate without an open flame. Ideal for apartment or condo dwellers since they don’t require charcoal or propane.

Kamado: For people who love cooking all styles and seasons. Kamado grills’ excellent insulation is ideal for both grilling and smoking. They can use wood and charcoal and are ideal for roasting and baking.

Questions to ask before buying a grill

What do you love to cook? Many grills come with extra features ideal for certain foods, like rotisseries if you love a roasted chicken, side burners if you love soups and stews, or ample space for pizza stones if you frequently crave the ‘za.

How much time will you have to cook? If you’re hard pressed for free cooking time, consider the convenience of gas or electric grills. Love to pass the time cooking? A charcoal, smoker or kamado grill may be best for you.

How much space do you have? If you have a big backyard, consider a larger grill perhaps with a kitchen island to create a focal point for relaxation and entertaining. Premium portable or more compact grills are ideal for condos and apartments.

Once you have your grill at home and ready to go, it’s time to get cooking. Raichlen shares one of his favorite grill recipes below. Find more recipes, cooking tips and pledge to grill out at www.whyigrill.org.

Pamplona of Pork

Ingredients
2 pork tenderloins, each 1 to 1-1/4 pounds
Coarse salt – sea or kosher – and freshly ground black pepper
3 tablespoons Dijon mustard
1 roasted red bell pepper, stemmed, peeled, seeded and sliced into 1/4-inch strips (see note below)
3 ounces thinly sliced smoked ham, slivered
One 5.2-ounce package Boursin cheese or other soft garlic and herb cheese, crumbled
4 strips thin-cut bacon
Vegetable oil for oiling the grate
You’ll also need: Butcher’s string; 1 or 2 hardwood chunks or 1-1/2 cups hardwood smoking chips. If using the latter, soak in water to cover for 30 minutes, then drain.
Directions
1. Set up your grill for indirect grilling and heat to medium-high, about 400 degrees.
2. Meanwhile, cut a deep pocket in the side of each pork tenderloin. Season the inside of the pocket with salt and pepper and paint with mustard. Stuff the peppers, ham and cheese into the pocket. Season the outside of the tenderloins with salt and pepper.
3. Lay four 10-inch pieces of kitchen string on and parallel to your work surface. Lay a strip of bacon on and perpendicular to the strings. Top with one of the tenderloins. Lay a second strip of bacon on top of the tenderloin. Bring up the ends of the strings and tie. Trim the ends close to the knots. Repeat with the remaining tenderloin.
4. Brush or scrape the grill grate clean and oil it well with vegetable oil. If using a charcoal grill, add the wood chunks or chips to the coals. On a gas grill, place in the smoker box or under the grate directly over the burners.
5. Indirectly grill the tenderloins until nicely browned and the meat is cooked through to 145-155 degrees or as needed, about 40 minutes.
6. Let the meat rest for 5 minutes. Remove the strings, then, using a sharp knife, preferably with a serrated blade, slice the tenderloin crosswise into 1/2-inch medallions. Transfer to a platter or plates.
Note: The pepper can be prepared at a previous grill session. Heat the grill to high then roast the pepper until the skin is blackened and charred, 2 to 3 minutes per side. Alternatively, roast the pepper over an open flame on your gas stove or the side burner of your grill. Cover and refrigerate for up to a day if not using immediately.

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When Feeling Dizzy Should Raise Health Concerns

2021-05-14T08:01:00

(BPT) – While on a family vacation in Europe, Keith suddenly felt lightheaded and fell in the bathroom. At the time, he didn’t think much of it. Years later, he and his wife were renovating a bathroom in their house, and he fell down the stairs after getting lightheaded. He was lucky enough not to be injured, but it was a wakeup call to finally talk with his doctor about what he had been experiencing.

How do you know when feeling lightheaded or dizzy is part of a larger medical condition? For those living with Parkinson’s disease, multiple system atrophy (MSA), or pure autonomic failure (PAF), dizziness, blurry vision, or leg buckling can be symptoms of a separate, manageable condition called neurogenic orthostatic hypotension (nOH).

Symptomatic nOH affects approximately 20% of people diagnosed with Parkinson’s. When a person without nOH stands up, gravity naturally pulls the blood to the lower part of the body, lowering blood pressure. When this happens, the nervous system typically releases a chemical called norepinephrine, which signals the blood vessels to tighten, or constrict. This raises blood pressure and makes it easier for the body to pump blood back up to the heart and brain. For a person living with nOH the body does not release enough norepinephrine upon standing. As a result, blood vessels are unable to tighten as they should, preventing the blood from being pumped back up to the head and upper torso.

Keith had already been diagnosed with Parkinson’s, so when he opened up to his neurologist about the symptoms he had been experiencing, his doctor was able to perform tests and ultimately diagnosed him with nOH. Since nOH is a manageable condition, Keith was able to start on a treatment regimen that worked for him.

If you or a loved one is living with a neurodegenerative condition and can relate to Keith’s story, consider taking the following steps in preparation for speaking with your doctor.

  • Track Your Symptoms: Use a tracker or notebook to write down your symptoms and how often you experience them. Capturing these details can help your doctor recognize potential patterns and make an informed diagnosis. To make tracking easier, a symptom tracker is available at nOHmatters.com.
  • Make a List of Questions: Writing down questions for your doctor in advance can be helpful for many patients. Consider asking things like, “Given that I have a nervous system disorder and my symptoms occur after standing or changing positions, could I have nOH?” and “What symptom management options are available?” A list of additional questions to consider can be found in the doctor discussion guide on nOHmatters.com.
  • Talk About the Impact. Discussing the impact your symptoms are having on your daily life, such as interfering with your hobbies or limiting your activity, can provide valuable insight for your doctor and allow them to work on a symptom management plan with you.

For more information on nOH, including a symptom checker and additional stories like Keith’s, visit www.nohmatters.com.

References

  1. Metzler M, Duerr S, Granata R, Krismer F, Robertson D, Wenning GK. Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management. J Neurol. 2013;260(9):2212-2219.
  2. Freeman R. Clinical practice. Neurogenic orthostatic hypotension. N Engl J Med. 2008;358(6):615-624.
  3. Ha AD, Brown CH, York MK, Jankovic J. The prevalence of symptomatic orthostatic hypotension in patients with Parkinson’s disease and atypical parkinsonism. Parkinsonism Relat Disord. 2011;17(8):625-628.
  4. Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res. 2011;21(2):69-72.
  5. Goldstein DS, Sharabi Y. Neurogenic orthostatic hypotension: a pathophysiological approach. Circulation. 2009;119(1):139-146.
  6. Low PA. Neurogenic orthostatic hypotension: pathophysiology and diagnosis. Am J Manag Care. 2015;21(13 Suppl):s248-s257.

©2021 Lundbeck. All rights reserved. UBR-D-100893

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5 things parents should look for in a children’s mobile app

2021-05-14T15:01:01

(BPT) – With so many apps out there it can be challenging to identify which ones can help kids have fun and build new skills. Applaydu, Kinder Joy’s new app for families made with guidance from Oxford University, does both. Now free in the App Store and Google Play, Applaydu is full of games, stories and opportunities that can promote creativity and exploration for kids.

“Kinder has always been about creating special moments when parents can connect with their children and we’re finding new ways to make those moments even more memorable,” said Felipe Riera Michelotti, vice president of marketing, Kinder®, North America. “With a whole world of games and activities to explore in Applaydu, even more surprises and special moments are in store for families with each Kinder Joy egg.”

What should parents look for in mobile apps?

If you’re looking for a mobile app with activities for playing and learning, here are some of the features you should look for:

A variety of skill-building activities

When mobile games only provide players with a singular task, it’s often not challenging them enough for them to stay engaged. But a variety of experiences can allow players to expand their skills in different areas.

Applaydu comes with minigames that your child can play to enhance their motor, organizational, memory and rhythm skills. These minigames can also teach them about different subjects, including math, geography, and music.

Tasks that help your child learn new vocabulary words

No matter your child’s age, they can always benefit from learning new words. And when they hear vocabulary in a story, it can help them remember those words and apply them in real life.

Applaydu introduces words through personalized stories that aim to help build vocabulary. Once the player finishes the story, it gets stored in the player’s “personal library.”

Fun rewards for learning

Incentives and rewards systems can be effective for motivating any game player to move on to the next big adventure, and can also be used to give kids confidence to tackle the next reading or math challenge.

With new vocabulary words learned or math concepts tackled, Applaydu allows players to unlock gifts like 3D characters, avatar costumes and personalized adventure books.

Parental controls

It’s hard to manage a child’s screen time without information. With Applaydu, parents can get a pin-protected password that can allow them to track their child’s progress and see what they are learning and what they have accomplished.

If you’re looking to discover more with Applaydu, head to the App Store or Google Play to download, and pick up Kinder Joy Treat + Toy online and at stores nationwide.

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How to use less data and save money on your wireless plan

2021-05-14T11:35:20

(BPT) – Does your lifestyle require an unlimited stream of data? At first glance, there’s probably nothing wrong with this assumption: After all, think about how much of your day is spent on data-dependent activities like streaming video and music, or searching the internet.

But all of this can be done while using far less, and sometimes even none, of the data from your cellular plan. Try these simple tips to save money on your wireless plan.

1) Tame the video beast

Watching video on your smartphone is convenient, but it’s a data glutton. A full-length Netflix movie consumes about 1GB of data per hour in standard definition video, and up to 3GB per hour in high definition. At that rate, you’ll burn through even the most robust data package in no time.

Try connecting to Wi-Fi instead. It’s widely available, and lets you stream without using any cellular data at all, often with a faster connection. While connected to Wi-Fi, you can also download videos, TV shows or movies to your phone or SD card to watch at your convenience, with no data required.

In addition, when you’re streaming video on a small screen, such as a cellphone, you really don’t need high resolution. Many apps give you the ability to change video quality settings, and therefore consume less data. For Netflix, log into your account and switch to one of three settings: low (using 0.3GB per hour), medium (which uses 0.7GB per hour) or high (using up to 3GB per hour). In the YouTube app, just tap the three-dots menu and click “Quality” to lower it.

2) Manage social media and streaming music

Videos have also become a standard part of the social media experience. Adjusting your settings to prevent videos from playing automatically will prevent them from eating up your data. The steps to change this setting can vary between applications. On most platforms, like Facebook, you’ll go to your Account Settings and either disable the “Autoplay” feature or change it so that videos will only play automatically when you’re connected to Wi-Fi.

Popular audio streaming apps offer ways to listen to your music without having to use a network connection, or even Wi-Fi. Spotify lets you download your albums and playlists right to your device. If you use Apple Music, you can add songs, albums and playlists to your library.

3) Try a smaller plan for bigger savings

While an “unlimited” plan may seem like an easy answer to your data needs, they can be more enticing than practical. Read the fine print: Most actually limit your high-speed data to a certain number of gigabytes per month. Once you use up that allotment, you’ll still have unlimited access, but at much slower speeds. This makes it more difficult to load pages quickly, or to stream video, even though you’re paying a premium for “unlimited” access.

Instead, a carrier like Consumer Cellular offers a range of choices from a talk-only 250-minute plan to 3GB, 10GB, 15GB or unlimited data options each month. Plans are also flexible: You can switch up to the last day of a billing cycle with no extra fees, and you’re also automatically upgraded if you go over your data usage. That means you get the best rate for what you use, rather than having to carry an unlimited plan just to prevent an overage.

Follow these tips and you’ll enjoy streaming movies, listening to music and more while also keeping money in your pocket for things other than a data plan. You can have it all, without needing an unlimited budget to do it.

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3 tips for the best summer vacation this year

2021-05-14T10:27:00

(BPT) – Yearning to go on an adventure this summer? If you are, it’s a good idea to spend extra time planning for a successful vacation. A lot has changed over the past year, so a bit more planning, along with extra patience, will help make your family’s vacation as fun and as memorable as you want it to be.

Here are tips to help your summer vacation go smoothly — and safely — this year, so you’ll all have a blast.

1. Spend more time and effort making preparations

Even if you’re the “get there and wing it” kind of vacationer, this year you’ll be happier making as many reservations ahead as possible. With the travel season quickly heating up but many venues experiencing major staffing shortages, you’ll help lessen delays and wait times by planning ahead.

Help make everything go more smoothly by making reservations for everything from your lodgings and rental cars to dining out and tourist attractions. Check venue websites or call to ask if you can reserve (or must reserve) ahead to help avoid long waits.

2. Plan for shifting protocols

As everyone has learned this past year, things can change quickly. To prepare for changes in safety policies, check websites for airlines, hotels and venues you’ll be visiting for their current guidelines. Bring enough masks and hand sanitizer for your whole family and keep them handy when venturing out. Continue wearing masks at indoor venues and crowded outdoor venues where social distancing is not possible — and remind your family to continue washing hands frequently. When in doubt, ask employees about their current protocols and be sure to comply with their requests to keep everyone safe and comfortable — staff and visitors included.

3. Focus on outdoor fun

Summer is all about getting outdoors, and while health is still a concern, outdoor venues offer the safest opportunities to enjoy your family trip. Fortunately, you can find something for everyone in your family at The Beach — Myrtle Beach, South Carolina. Here are great options for family fun at Myrtle Beach:

  • The Beach: Beyond the 60 miles of wide-open beaches throughout the Grand Strand, check out lesser-known spots including laid-back Pawleys Island or Litchfield Beach, a quaint area with just two resorts. You can also find unspoiled beach access at Huntington Beach State Park and Myrtle Beach State Park.
  • Fishing: Myrtle Beach boasts endless opportunities to cast your line, from freshwater and inlet fishing to deep sea charters. The area’s eight piers offer day passes for fishing, and many also provide fishing rod rentals.
  • Biking and birding: Hit the trails on foot or on two wheels at Waccamaw Neck Bikeway, a 12-mile multi-purpose path between Murrells Inlet and Huntington Beach State Park. Or you can visit The Horry County Bike and Run Park (known as The Hulk) in Carolina Forest, or Vereen Memorial Historical Gardens in Little River, with 114 acres of salt marshes and woodland. Bike rental options include electric bikes at Pedego at The Market Common. For a more relaxed outdoor excursion, Huntington Beach State Park is home to one of the best birding spots on the East Coast, with over 300 species of birds on its grounds throughout the year.
  • Golf and miniature golf: Perfect your swing at one of nearly 100 championship golf courses, including the iconic Pine Lakes Country Club, the area’s oldest course. If putting is more your speed, check out one of the over 35 elaborately themed miniature golf courses depicting swashbuckling pirates, volcanoes, dinosaurs and more.
  • Historic walking tours: The charming inland town of Conway features historic buildings listed on the National Historic Register, and Georgetown is one of the state’s oldest cities on the south end of Myrtle Beach, offering an unmatched historic waterfront. You can grab a self-guided tour brochure at the visitor center or sign up for a Strollin’ on the Sampit Walking Tour led by a local guide for just $8.

Do you belong at The Beach? Visit Myrtle Beach and its partner organizations continue to maintain their Healthy Travel section on VisitMyrtleBeach.com, with the latest COVID-19 updates and mandates. To plan your next great family vacation, check out VisitMyrtleBeach.com or call (888) Myrtle-1.