Why Wyoming is topping travel itineraries this year

2021-07-30T15:11:48

(BPT) – After altering travel plans for over a year, families across the country are ready to satisfy their wanderlust again. With an eye on safety, road trips and traditional family activities are making a comeback as people are hitting the highway to visit states that offer good fun and plenty of room to roam. That’s why heading to Wyoming to experience the best of the West, like rodeo, hiking and fishing, is topping travel itineraries.

Make memories enjoying the best of Western culture

Special events like fairs and rodeos make a trip memorable, but there’s so much more your family can do to experience the Western culture that’s helped define United States history. The great outdoors await in Wyoming, with the same beauty found today as hundreds of years ago when the West was first being explored.

Some of the best ways to experience Mother Nature at her finest are fly-fishing the North Platte River, hiking Casper Mountain, visiting the National Historic Trails Interpretive Center or the Tate Geological Museum, exploring the Platte River Trails or Fremont Canyon — which can fill in the days before or after all that rodeo action.

Offering a small-town feel with big heart, carve out time in your itinerary to wander downtown Casper. Unique boutiques and a host of restaurants, breweries and a distillery are welcoming visitors, so you can kick back, sip on libations and enjoy exceptional cuisine. Finally, head over to Lou Taubert Ranch Outfitters to get your gear and feel like a cowboy (even if you haven’t ever ridden a horse). Home to nine floors and 10,000 pairs of cowboy boots, the whole family will be looking the part, plus you’ll have the perfect attire for that next family portrait or holiday card.

Kick up your heels and see the action at a rodeo

Rodeo is the state sport of Wyoming and the mountain town of Casper is host to the biggest rodeo events in the West. At the College National Finals Rodeo — commonly referred to as CNFR, top collegiate rodeo athletes compete in events that include bareback riding, tie-down roping, breakaway roping, saddle bronc riding, steer wrestling, goat tying, team roping, barrel racing and bull riding. Learn more at cnfr.com.

Learn more about all these activities and get many more ideas for family vacationing at www.visitcasper.com.

Planning your dream outdoor room? How to manage the budget

2021-07-30T10:25:50

(BPT) – As the pandemic continues, outdoor spaces have become true extensions of the home. From a calm place to escape to an area to work and focus, outdoor rooms are being designed and utilized more frequently than ever before.

“Homeowners have shifted their focus from having spaces to entertain to making their homes more functional,” says Joe Raboine, director of residential hardscapes, Belgard. “With the increased time spent at home, outdoor spaces have become a haven for both recreation and relaxation, as well as a valuable asset when it’s time to resell.”

With over 25 years as an outdoor designer, Raboine has insight into the outdoor living industry. He expects biophilic design trends to gain momentum as people continue craving a connection to nature. This design approach prioritizes customizing spaces that flow with the natural landscape, benefitting human health and environmental wellness.

Some of the most popular room additions that complement a property are outdoor dining rooms, living rooms, kitchens and offices.

Planning the right outdoor room for you

If you are considering adding a dream outdoor space to your property, it’s important to properly plan. Start by exploring designs and building plans that might be right for your needs and space.

Belgard Rooms offers a resource for planning outdoor rooms. The interactive site at Belgard.com/Rooms makes it easy to identify needs, pair designs that complement the style of your home and define your overall plan. Once you find one you like, you can download the plan for free and share it with contractors to get bids on the project.

“[The site] is segmented by room type and structured around how shape, color and texture work together to offer more options and make the design planning process easier,” says Raboine.

Beyond convenience, this is beneficial from a timing and installation perspective. The templated designs can be customized to fit homeowners’ needs and tastes. This means contractors require less time for the design and installation process, and you can enjoy your outdoor space sooner.

4 tips to manage your budget

After you find a plan you like, it’s time to consider budget and connecting with contractors. This insight from Raboine will help you in managing the budget:

1) Research typical project costs in your area

Ask neighbors if they have completed similar projects. Get multiple quotes from several contractors. Go beyond labor costs and determine product costs online to understand the big picture financially. To give yourself options, look for alternative products that are similar in price.

2) Research contractors and gather bids

Get multiple bids from contractors. Given the current circumstances, this year is busy for contractors, in terms of scheduling and inventory. Keep in mind price is only one consideration; experience, licenses, references, turnaround time and satisfaction guarantees are other important factors.

3) Determine a payment schedule

Understand payment options and if materials are included in those fees. You may want to plan the project in phases to meet your budget. Additionally, you can ask about financing options, which may allow you to take advantage of construction efficiencies and avoid a phased build.

4) More complex projects cost more

Make sure you understand specific construction or engineering requirements. Linear design requires less cutting and building, resulting in lower costs compared to circular or winding patterns. Leveling your land can be costly, so consider building down into the slope.

“Schedules for contractors nationwide are filling up, so now is the time to take action with your outdoor projects by finding designs you like, gathering bids and making your dream outdoor room a reality,” said Raboine.

Smart Tips And Tricks For Teaching Kids Good Financial Habits

2021-07-28T09:17:00

(BPT) – As kids across the country are gearing up to head back to school, parents and caregivers are looking forward to their children learning new lessons and skills, full of fun and education. While school is a primary place for students to learn, some of the most impactful lessons actually start at home — particularly about money and developing healthy financial habits early.

“A good understanding of how to be responsible with money starts with what kids see and learn at home,” says Radhika Duggal, CMO of Community & Business Development at Chase. “It’s important to bring your kids into conversations about money and include them in family financial decisions to help them understand how to budget, save and spend responsibly. What we do as parents today can help position them to understand money in the future.”

Duggal shares some simple things you can do today to help with the money talk:

Start with the basics

Have an open discussion as a family about how money is earned and spent. Discuss “needs” versus “wants” and how to balance both while also saving money for the future. Kids may realize that it costs money to buy groceries from the store, but may not understand other monthly household expenses, like water, WiFi or electricity.

Build a budget

Discuss budgeting basics in age-appropriate language and get kids involved. For younger kids, bring them into the conversation when making a grocery list and show how you plan, budget and buy ingredients for a family meal. For tweens and teens, discuss how to plan and budget for their summer activities with friends. Show them why it’s important to revisit your family’s budget as priorities or expenses may have changed.

Set goals and make a plan

Share some of your financial goals with your children, whether it’s something in the near future like saving for a new TV or a longer-term goal like saving for 529 plans. Then, help kids make a list of things they would like to save for — an item or experience — and create a plan for achieving those goals. Beyond individual goals, families can also work together to set and achieve common financial goals, like saving for a big vacation or college.

Consider kid-friendly financial tools

Consider helping your kids learn through real financial tools — like a debit card, bank account or investment account. Chase offers Chase First Banking — a debit card for kids ages 6 to 17 with no Monthly Service Fee that gives parents the control they want and kids the freedom they need to learn. Parents can set spending limits, track their child’s purchases and even help them with savings goals. Tools like First Banking offer set parameters to give parents peace of mind, while helping your child learn how to be responsible with their money. Through September 2, receive a bonus when you open a new Chase First Banking account. You just need a qualifying Chase checking account to apply. For more information go to www.chase.com/firstbanking.

Create a system for earning money

Help kids understand the relationship between work and reward by setting up a system for them to earn money. Every family is different in what works best for them, but some common approaches are weekly allowances for chores. Other ways to earn money include setting up a side job like a lemonade stand, mowing lawns or babysitting in the neighborhood. Because the child’s Chase First Banking account is connected to the adult’s checking account, transferring money earned is easy through the app.

Be a role model

Children absorb what you say and do. Kids will often mimic your financial habits, so remember you are a role model. Keep financial topics a regular part of family conversations and ensure your kids feel comfortable coming to you with any money questions they have, no matter how big or small. For example, if you are eligible for the current Child Tax Credit — which Chase and non-Chase customers can cash at Chase with no fee — consider discussing with kids where the money came from and how you wish to spend/save it.

Returning to School with a Smile: Tips & Tricks

2021-07-27T23:01:00

(BPT) – Many students and parents are preparing to head back to classrooms this fall for the first time in over a year. Amazon has compiled tips and tricks to help students — and parents! — keep back-to-school jitters at bay so they can head back to school with confidence.

1) Create a family countdown calendar. Help your children think of the first day of school as a celebratory moment worth counting down, like the holidays or a birthday. As a family, create and decorate your own calendar leading up to the first day of school. Each day, ask your child to share one thing they are looking forward to this school year. These conversations that focus on positive aspects of the new school year will help you and your child look forward to the new experiences they’ll have when school is back in session.

2) Stock up for success. With every new school year comes a checklist of supply lists and refreshed wardrobe needs. Amazon makes it easy to get all your back-to-school needs in a convenient one-stop-shop with great value and free shipping right to your doorstep. You can even shop by grade level and category so you can find everything on your school list. Include your children in the process of selecting items from fun backpacks and lunchboxes to crayons, pens and notebooks. Enlist their help in checking off their school supplies list so they can feel good about how prepared they are for the first day of school.

3) Take the stress out of shopping with Amazon Prime. Forgot an item on your school supplies list? No problem! Prime members can take advantage of unlimited Free One-Day Delivery, with no minimum purchase amount. To help you stay even more organized leading up to the first day of school, Prime members can choose when to have their orders arrive with Amazon Day delivery — simply pick a day that works for you, shop the supplies you need throughout the week, and Amazon will deliver all your orders together on the day you choose.

4) Practice your routine with a dress rehearsal. To help acclimate your children to a new schedule and feel confident in their morning routine, try having a first day of school “dress rehearsal.” Set alarms early, lay out clothing the night before, and get ready as you would on the first day of school. This way your child will know exactly what to expect. Plus, a run-through will allow parents to anticipate any last-minute needs in advance — a win-win!

5) Give back while you shop for back to school. One of the best ways to feel good, is to do good! Amazon makes it easy to support your favorite charity every time you shop, including education-related charities and PTAs, at no extra cost. Visit smile.amazon.com to find the exact same Amazon shopping experience — amazing deals, wide selection, fast and free delivery options — and AmazonSmile will donate a portion of the eligible purchase price to the charity of your choice.

Find classroom essentials, back-to-school fashion, and more and at amazon.com/backtoschool.

5 things you may not know about the power of plasma

2021-07-27T11:51:49

(BPT) – You’ve heard all the stories about the importance of donating blood, but you might not be as familiar with the other lifesaving substance flowing through your veins — plasma. While the world is focused on the important issue of a blood donor shortage, there’s an equally critical need for plasma donors as a result of the pandemic. The shortage of plasma could impact many people who rely on these lifesaving plasma-based therapies. Your help makes the difference in someone’s life by donating plasma.

Below are 5 frequently asked questions about plasma.

1) What is plasma? Plasma is the fluid component of human blood. It supports essential bodily functions, including red blood cells, white blood cells, clotting factors and other components to fight deadly diseases. Plasma is also used to treat patients with serious diseases and conditions, like burn injury survivors, people with hemophilia, people with rare diseases and people with certain types of cancer.

2) Why is it so important to donate? A lot of plasma is needed for each patient who relies on these therapies to survive. For example, it takes 1,200 plasma donations to treat 1 patient with hemophilia per year. It can take up to a whole year to make plasma-derived medicine, so a decline in plasma donations could impact patients’ ability to access their medications.

3) Do that many people really use plasma? Yes. 125,000 Americans rely on medication made from plasma. These treatments can mean the difference between life and death for patients who suffer from a variety of chronic conditions, like primary immunodeficiency diseases and hemophilia. Without regularly receiving these medicines, patients may suffer chronic fatigue, physical damage or even death.

4) Why are we talking about this now? There is a serious shortage of plasma donors in the U.S. Shutdowns during the COVID-19 pandemic contributed to the plasma supply decreasing by more than 20%. The supply has been declining for more than a year, and that trend doesn’t seem to be shifting. The need has never been greater for people to donate plasma.

5) Is it easy to donate? Yes. You can donate plasma twice a week since plasma is replaced within about 24 hours, whereas red cells need between 4-6 weeks to be replaced. In less than two hours, your plasma can make a lasting impact by providing lifesaving medicine for those who need it, when they need it most.

How you can help

“The pandemic has impacted all Americans, but its lingering effects on plasma donations are frightening for those who rely on plasma-derived therapies, including the tens of thousands of immunocompromised patients,” said John Boyle, a patient and health advocate who relies on plasma-based therapeutics to live a normal life. “We haven’t seen this type of plasma shortage before, and that’s why we’re calling on everyday heroes to step up and donate plasma now to help save lives.”

Plasma donation centers are available throughout the country, with more than 800 centers nationwide. Donation centers are staffed with medically trained professionals to help you through the donation process. A list of centers can be accessed at: https://www.donatingplasma.org/.

Natural solutions for pesky mosquitoes

2021-07-27T08:01:00

(BPT) – Gatherings with family and friends are back! Also back? Mosquitoes and other flying insects that annoy, irritate and generally make outdoor activities less enjoyable for everyone. Fortunately, there are simple and effective ways to keep bugs at bay and the outdoor adventures going strong.

“You don’t have to resort to chemical mosquito repellents if bugs are bothering you,” says Brandon Roach, executive vice president of New Product Development and Engineering at Skeeter Hawk, a brand with a full line of all-natural mosquito and flying insect defense products. “A few smart strategies and natural tools will help you and loved ones keep mosquitoes away.”

Whether you’re going on a walk, relaxing on the patio or hosting a gathering in your backyard, you want to enjoy your time outdoors. Here are seven natural solutions to solve mosquito problems:

1) Avoid standing water

Mosquitoes lay their eggs in standing water, so at home, eliminate places in your yard where water accumulates, such as buckets, pots and lids. Put containers away or turn them over so they don’t catch water. For things like pools and bird baths, remember to keep water fresh.

2) Add perimeter protection

Like an invisible forcefield, a Skeeter Hawk Mosquito Trap can be used in your favorite outdoor spaces like campsites, pools and backyard patios. These effective traps use a whisper quiet fan and long-lasting patent-pending UV LED technology to attract and trap mosquitoes and other flying insects.

3) Circulate air

When air is calm it’s easy for mosquitoes to fly around. When it’s windy, mosquitoes have a more difficult time getting where they want. Therefore, if you’re hosting a gathering at your home and air is stagnant, consider running fans if possible. You may add portable fans to patios, decks and other outdoors areas where people gather.

4) Cover up

Add a barrier between yourself and mosquitoes with your clothing. Even during warm weather you may opt for cotton clothing that breathes to keep you cool. In addition to shirts and pants that cover your skin, consider skipping the sandals and wear socks and closed-toe shoes to protect feet and ankles. Wearing a hat helps protect your head, too.

5) Wear personal repellents

When bugs are bugging you, you don’t need to resort to heavy chemical repellents. Skeeter Hawk offers personal wristbands and carabiners that are portable and easy to wear, repelling bugs with all-natural essential oils not dominated by citronella. Just wear on the wrist or ankle, or add to a belt loop or backpack. No bugs, no foul smell.

6) Wear lighter colors

Research shows that dark colors like black, navy blue and red are more attractive to mosquitoes. When deciding what to wear before heading outside, consider light colors that not only keep you cool, but also help repel these insects. Whites and pastels may be a good option.

7) Avoid perfumes

Strong smells are like a siren call for mosquitoes, so the next time you’ll be heading outdoors, skip the perfume or cologne. Don’t forget about other strongly scented products you may use including deodorant and soaps. You may not be able to limit use of these personal products, but you can opt for light or no-scent versions.

For more information about mosquitoes and natural options for keeping them at bay, visit skeeter-hawk.com. Products can be used independently or in combination for layers of customized protection so you can fully enjoy the outdoors.

How pet-friendly policies can ease the transition back to the office

2021-07-27T08:01:00

(BPT) – With many offices welcoming back employees over the next few months, employers and employees alike are wondering what their new workplace will look like, and how smoothly the transition will go. Working from home has had plenty of challenges over the past year, but also has offered many people the ability to spend more time with their beloved pets.

In a recent 2021 study, roughly 3 out of 4 (76%) pet owners said they’ve been happier working at home with their pets by their side. The survey, conducted on behalf of Purina, also found that 73% of pet owners currently working from home are worried about how their pets will react to their absence once they return to the office.

One way to address potential separation anxiety for both pets and pet owners is by cultivating a pet-friendly workplace. A pet-friendly office can help smooth this new transition, keep employees engaged, and help recruit — and retain — top talent. In the survey, 72% of pet owners working from home said they would accept a job offer from a pet-friendly employer over a non-pet-friendly employer, assuming salary and other benefits were equal. And nearly half (48%) of pet owners whose company doesn’t currently have a pet-friendly office thought that morale would improve if they did.

How can pets improve the workplace?

Studies have shown that employees who bring their pets to work tend to have a lower stress level by the end of the day and having pets by our sides can help reduce blood pressure, decrease loneliness, help to lower cholesterol levels and encourage physical activity with outdoor walks to break up the time spent sitting at a desk.

Pets can also have a beneficial impact on facilitating social interactions between employees who are looking to ease back in to reconnecting face to face with coworkers. In fact, 72% of C-suite leaders said that they believed a pet policy would either lead to — or already has led to — positive socializing in the workplace.

How do employers feel about a pet-friendly workplace?

Attitudes toward pet-friendly offices are changing, with many executives seeing the positive benefits of creating work environments more dedicated to employee happiness and well-being. In the survey, 65% of C-suite leaders whose office did not have a pet-friendly policy said that management would consider adopting one if 50% or more of their employees were in favor of it. And while some may worry about pets as a distraction, 56% of C-suite leaders said that a pet-friendly policy would lead to or has already resulted in increased productivity in the workplace.

“As a champion for pet-friendly workplaces and a pet-friendly employer for more than 20 years, Purina knows that such policies can lead to a clear increase in employee satisfaction and add a new dimension to the associate experience,” said Nina Leigh Krueger, CEO and President, Purina. “Now is the time to seriously consider the role that pets have had and will continue to have in the lives of employees. Introducing those pets into the workplace creates a cultural shift that brings people together, offers stress relief and fun, and increased productivity, all while helping the pets who have supported us throughout this time adjust to their own post-pandemic reality.”

Want to introduce a pet-friendly workplace?

For employees

Are you an employee interested in helping your office become pet-friendly? Visit Purina.com/Better-With-Pets/Pets-At-Work/Employee-Toolkit for resources and suggestions for how to bring up the topic with your employer. The toolkit includes information about how pets in the workplace reduce stress and other benefits, plus information about proper pet etiquette in your work environment.

For employers

Business owners and executives can check out the Purina.com/About-Purina/Better-With-Pets/Pets-At-Work/Employer-Toolkit for steps on how to make your workplace pet-friendly. It provides information about how to survey your employees on the topic, paperwork you may need to complete and ways to get your employees involved in the process.

For many people, pets are and will continue to be a huge part of their lives. Companies that encourage pets in the workplace show that they are committed to creating healthy work-life balances as we adjust to a new reality and continue to improve how we work and collaborate day to day.

Is it broken? What to do when a kid’s injury is more than just a bump or bruise

2021-07-27T06:01:00

(BPT) – Ouch! Kids break bones in many ways. Whether from a fall, a sports-related injury, roughhousing or just an accident, a broken bone isn’t something to take lightly. But, how do you know if it’s broken and what should you do next?

Know the signs

Broken bones are most common in the upper and lower extremities (limbs). The upper extremities include the arms, elbows, wrists and fingers and the lower extremities include the legs, knees, ankles and feet. Tendon and ligament injuries (sprains and strains) can happen in these areas as well, but don’t occur as frequently in children.

If your child has an extremity injury, there are a few ways to determine if they need to be seen immediately or if it can wait until later. Some symptoms may seem obvious; others may not. The general signs of a fracture are pain, bruising and swelling with tenderness over the area involved.

If the child or adult heard a snap or grinding sound when the injury occurred, it’s more likely to be a fracture, but not necessarily.

What should you do if you think it’s broken?

The severity of your child’s injury will determine the level of care they need. If the area isn’t deformed, extremely swollen or bruised, immediate medical attention may not be necessary. You’ll still want to make an outpatient appointment so a doctor can conduct an exam and X-rays if needed.

Your child will need immediate medical attention if:

  • There is a break in the skin and bone is showing.
  • They can’t bear weight on or use the extremity 15 minutes after the injury occurred.
  • The pain is uncontrollable with rest, elevation, ice and over-the-counter pain medicine.
  • There is a suspected neck or spine injury.

There are some things you can do at home to begin helping right away

Cut or remove clothes

If the arm or leg appears misshapen or swollen, carefully remove or cut clothing surrounding the affected area.

Try to reduce swelling

Apply a cold cloth or ice-wrapped towel to the swollen area. Avoid putting ice directly on the skin (without a cloth or towel), as it could result in frostbite.

Make a temporary splint

A makeshift splint can be used to help limit movement and prevent further injury until you can see a medical professional. You can create a makeshift splint with soft padding and something firm, like cardboard or folded-up newspapers, wrapped with an elastic bandage.

Broken bones can heal with the proper treatment

The doctor will provide specific direction, but kids usually need to wait at least three to six weeks before resuming normal activities so their broken bone can fully heal. The bigger the bone, the longer healing usually takes.

There are bone injuries that are more concerning. Fractures through the growth plate, fractures into the joint, and fractures that injured the nervous or vascular bundles can have long-term consequences. While breaking a bone can seem scary, with the proper medical attention and treatment, your child’s injury will heal, and they can go back to doing the things they love.

You know your child best. If you have concerns or are uncertain about the severity of the injury, it’s always best to seek treatment right away.

Learn more about bumps, bruises and broken bones from Children’s Hospital of Richmond at VCU at chrichmond.org/brokenbone.

Understanding When Depression May be Something More: Identifying and Managing Bipolar Depression

2021-07-26T07:01:01

(BPT) – It is common for people to experience both periods of happiness and sadness throughout their lives, but it can be hard to determine whether prolonged versions of these emotional states indicate something more serious than changing feelings. Sharp mood swings between extreme highs and extreme lows can often be a sign of a mood disorder. Bipolar disorder, also known as manic-depressive disorder, is a lifelong serious mental health condition that causes debilitating, severe mood swings and changes in energy and activity levels.[1] An estimated 5.8 million adults in the U.S. experienced bipolar disorder in the past year.[1]

Identifying Depressive and Manic Episodes

When symptomatic, most people living with bipolar disorder spend more time in the depressive phase, called bipolar depression.[2] Major depressive episodes in bipolar depression may cause depressed moods, fatigue, loss of interest in activities, or even suicidality.[2] Alternatively, a person experiencing a manic episode may express increased energy and activity, unusual talkativeness, agitation, risky behavior, distractibility, and poor decision making.[2] People living with bipolar disorder experience a 10-30 times higher rate of suicide, compared with the general population.[3]

During a manic or hypomanic episode, individuals living with bipolar disorder may have an elevated mood and an exaggerated sense of self-confidence, and they are less likely to characterize their behavior as risky or problematic.[2] Most of these individuals are likely to seek treatment during a depressive phase because depressive symptoms may be more troubling, negatively impact their quality of life, and cause functional impairment.[2],[4]

Challenges in Diagnosing Bipolar Depression

Bipolar depression can be difficult to diagnose, in part because people living with the condition are likely to experience other conditions with similar symptoms like anxiety disorder or Attention-Deficit Hyperactivity Disorder (ADHD).[5] Additionally, bipolar depression is commonly misdiagnosed as unipolar depression – or frequent depressive episodes without mania or hypomania.[5] In fact, only 20% of people with bipolar disorder who are experiencing bipolar depression are diagnosed correctly within the first year of seeking treatment.[6]

Dr. Roger S. McIntyre, M.D., FRCPC, Professor of Psychiatry and Pharmacology, University of Toronto, Canada, has been working with people with bipolar depression for 20 years and knows the importance of getting the correct diagnosis. It is imperative for healthcare providers to take the time to fully learn and understand an individual’s lived experiences, and that requires the individual to place significant trust in their care team. Once that trust is established, it allows for more productive conversations with people with bipolar depression and their caregivers about potential treatment plans.”

Getting the Proper Help

Talking to a healthcare provider about episodes of bipolar depression can be difficult, especially since people may feel embarrassed about their condition. “I always remind individuals that there is no shame in a bipolar depression diagnosis. With the right support and treatment, it is a manageable condition that is more common than many think,” says Dr. McIntyre.

Fortunately, there are treatments available to specifically treat bipolar depression that have been shown to reduce depressive symptoms. One such treatment is Latuda® (lurasidone HCl), a once-a-day prescription medicine FDA-approved to treat bipolar depression in adults, children, and teens (10 to 17 years).[7] In clinical studies, Latuda has shown efficacy in significantly reducing depressive symptoms in people with bipolar depression, with minimal side effects on weight, metabolic parameters, or prolactin.[7]

With the right caregiver support, healthcare team, and medication routine, those with bipolar depression can learn how to live a more balanced lifestyle and manage their symptoms. Before starting any treatment, people should talk to their healthcare providers to determine which treatment options may be right for them and to understand the potential benefits and risks.

For more information on bipolar depression and a discussion guide with tips on how to speak with your doctor about symptoms, visit www.latuda.com. Please see below for Important Safety Information.

IMPORTANT SAFETY INFORMATION AND INDICATIONS FOR LATUDA

INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS; and SUICIDAL THOUGHTS AND BEHAVIORS

Increased risk of death in elderly people with dementia-related psychosis. Medicines like LATUDA can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). LATUDA is not approved for the treatment of people with dementia-related psychosis.

Antidepressant medicines may increase suicidal thoughts or behaviors in some children, teenagers, and young adults within the first few months of treatment and when the dose is changed. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, especially sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. Report any change in these symptoms immediately to the doctor.

LATUDA may cause serious side effects, including:

  • Stroke (cerebrovascular problems) in elderly people with dementia-related psychosis that can lead to death
  • Neuroleptic malignant syndrome (NMS) is a serious condition that can lead to death. Call your health care provider or go to the nearest hospital emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever, increased sweating, stiff muscles, confusion, or changes in your breathing, heart rate, and blood pressure
  • Uncontrolled body movements (tardive dyskinesia). LATUDA may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop taking LATUDA. Tardive dyskinesia may also start after you stop taking LATUDA
  • Problems with your metabolism such as:
    • High blood sugar (hyperglycemia) and diabetes: Increases in blood sugar can happen in some people who take LATUDA. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes (such as being overweight or a family history of diabetes), your health care provider should check your blood sugar before you start and during treatment with LATUDA
      • Call your health care provider if you have any of these symptoms of high blood sugar (hyperglycemia) while taking LATUDA: feel very thirsty, need to urinate more than usual, feel very hungry, feel weak or tired, feel sick to your stomach, feel confused, or your breath smells fruity
    • Increased fat levels (cholesterol and triglycerides) in your blood
    • Weight gain. You and your health care provider should check your weight regularly during treatment with LATUDA
  • Increased prolactin levels in your blood (hyperprolactinemia). Your health care provider may do blood tests to check your prolactin levels during treatment with LATUDA. Tell your health care provider if you have any of the following signs and symptoms of hyperprolactinemia:
    • Females: absence of your menstrual cycle or secretion of breast milk when you are not breastfeeding
    • Males: problems getting or maintaining an erection (erectile dysfunction) or enlargement of breasts (gynecomastia)
  • Low white blood cell count. Your health care provider may do blood tests during the first few months of treatment with LATUDA
  • Decreased blood pressure (orthostatic hypotension). You may feel lightheaded or faint when you rise too quickly from a sitting or lying position
  • Falls. LATUDA may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills, which may lead to falls that can cause fractures or other injuries
  • Seizures (convulsions)
  • Problems controlling your body temperature so that you feel too warm. Do not become too hot or dehydrated during treatment with LATUDA. Do not exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. Do not wear too much clothing or heavy clothing. Drink plenty of water
  • Mania or hypomania (manic episodes) in people with a history of bipolar disorder. Symptoms may include: greatly increased energy, severe problems sleeping, racing thoughts, reckless behavior, unusually grand ideas, excessive happiness or irritability, or talking more or faster than usual
  • Difficulty swallowing

Do not drive, operate heavy machinery, or do other dangerous activities until you know how LATUDA affects you. LATUDA may make you drowsy.

Avoid eating grapefruit or drinking grapefruit juice while you take LATUDA since these can affect the amount of LATUDA in the blood.

Do not take LATUDA if you are allergic to any of the ingredients in LATUDA or take certain medications called CYP3A4 inhibitors or inducers. Ask your health care provider if you are not sure if you are taking any of these medications.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. LATUDA and other medicines may affect each other, causing possible serious side effects. LATUDA may affect the way other medicines work, and other medicines may affect how LATUDA works. Your health care provider can tell you if it is safe to take LATUDA with your other medicines. Do not start or stop any other medicines during treatment with LATUDA without talking to your health care provider first.

Before taking LATUDA, tell your health care provider about all of your medical conditions, including if you:

  • have or have had heart problems or stroke
  • have or have had low or high blood pressure
  • have or have had diabetes or high blood sugar, or have a family history of diabetes or high blood sugar
  • have or have had high levels of total cholesterol or triglycerides
  • have or have had high prolactin levels
  • have or have had low white blood cell count
  • have or have had seizures
  • have or have had kidney or liver problems
  • are pregnant or plan to become pregnant. It is not known if LATUDA will harm your unborn baby. Talk to your health care provider about the risk to your unborn baby if you take LATUDA during pregnancy
    • Tell your health care provider if you become pregnant or think you are pregnant during treatment with LATUDA
    • If you become pregnant during treatment with LATUDA, talk to your health care provider about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling 1-866-961-2388 or going to http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/
  • are breastfeeding or plan to breastfeed. It is not known if LATUDA passes into your breast milk. Talk to your health care provider about the best way to feed your baby during treatment with LATUDA

The most common side effects of LATUDA include:

  • Adults with schizophrenia: sleepiness or drowsiness; restlessness or feeling like you need to move around (akathisia); difficulty moving, slow movements, or muscle stiffness; and nausea
  • Adolescents (13 to 17 years) with schizophrenia: sleepiness or drowsiness; nausea; restlessness or feeling like you need to move around (akathisia); difficulty moving, slow movements, muscle stiffness, or tremor; runny nose/nasal inflammation; and vomiting
  • Adults with bipolar depression: restlessness or feeling like you need to move around (akathisia); difficulty moving or slow movements; and sleepiness or drowsiness
  • Children (10 to 17 years) with bipolar depression: nausea; weight gain; and problems sleeping (insomnia)

These are not all the possible side effects of LATUDA. For more information, ask your health care provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

INDICATIONS

LATUDA is a prescription medicine used:

  • To treat adults and adolescents (13 to 17 years) with schizophrenia
  • Alone to treat adults, children and teens (10 to 17 years) with depressive episodes that happen with bipolar I disorder (bipolar depression)
  • With the medicine lithium or valproate to treat adults with depressive episodes that happen with bipolar I disorder (bipolar depression)

References



[1] National Institute of Mental Health. “Bipolar Disorder Statistics.” Available from: https://www.nimh.nih.gov/health/statistics/bipolar-disorder.shtml. Accessed April 2021.

[2] Depression and Bipolar Support Alliance. Bipolar Disorder Diagnosis and Symptoms. [Internet]. Available from: https://www.dbsalliance.org/education/bipolar-disorder/diagnosis/. Accessed April 2021.

[3] Dome, P., Rihmer, Z., & Gonda, X. (2019). Suicide Risk in Bipolar Disorder: A Brief Review. Medicina (Kaunas, Lithuania), 55(8), 403. https://doi.org/10.3390/medicina55080403

[4] Sylvia, L.G., Montana, R.E., Deckersbach, T. et al. (2017). Poor quality of life and functioning in bipolar disorder. International Journal of Bipolar Disorders, 5, 10. https://doi.org/10.1186/s40345-017-0078-4

[5] Singh T, Rajput M. (2006). Misdiagnosis of bipolar disorder. Psychiatry (Edgmont), 3(10):57-63. PMID: 20877548, PMCID: PMC2945875

[6] Phillips ML, Kupfer DJ. (2013). Bipolar disorder diagnosis: challenges and future directions. The Lancet, 381(9878): 1663-1671. https://doi.org/10.1016/s0140-6736(13)60989-7

[7] Loebel, A., Cucchiaro, J., Silva, R., Kroger, H., Hsu, J., Sarma, K., & Sachs, G. (2014). Lurasidone monotherapy in the treatment of Bipolar I Depression: A randomized, double-blind, placebo-controlled study. The American Journal of Psychiatry, 171(2): 160-168. https://doi.org/10.1176/appi.ajp.2013.13070984.