Month: September 2024

2024-09-16T08:01:00

(BPT) – Do you or a loved one have non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations? We get it, that’s a mouthful. But if you know, you know.

What you might not know is there’s a new clinical trial for this specific diagnosis, part of a next-generation solution being developed to target NSCLC. To understand the significance of this trial, it’s important to grasp the underlying biology involved.

NSCLC is the most common type of lung cancer accounting for approximately 85% of lung cancer diagnoses worldwide (Source: Yale Medicine). According to WebMD, EGFR is a protein on your cells that helps them grow. When changes, commonly referred to as mutations, develop within the EGFR molecule, its normal function is altered which may allow cancer cells to grow and spread more rapidly. About 32% of NSCLC cases worldwide involve an EGFR mutation. These changes in the EGFR protein are referred to as classical, non-classical (or atypical/uncommon), or acquired mutations.

People at the highest risk of having EGFR-positive lung cancer include:

• Those who have never smoked or were a light smoker
• Those with lung adenocarcinoma
• Women
• Young adults with lung cancer
• People of Asian or East Asian heritage

Scientists are now beginning to grasp the landscape of EGFR mutations that fuel tumor growth. However, current targeted therapies may only act against a limited subset of these cancer-causing changes. Black Diamond Therapeutics (BDTX), a clinical-stage oncology company dedicated to providing people living with cancer the opportunity to live longer, healthier lives, is developing a treatment to target these mutations. The idea is to target a broad spectrum of EGFR mutations that can drive NSCLC with the goal of reaching a larger patient population.

What about its clinical trial?

BDTX-1535-101 is a Phase 2 clinical trial to evaluate one of the potential therapies Black Diamond has developed. Investigational therapy* BDTX-1535 is designed to address more than 50 EGFR mutations and is taken in pill form by mouth once a day. The trial is now enrolling patients with EGFR non-classical mutations who have not been previously treated, as well as patients who have had prior treatment with an EGFR inhibitor.

If you’re interested in learning more about the BDTX-1535-101 clinical trial (NCT05256290) including participation criteria, visit https://www.blackdiamondtherapeutics.com/patients/clinical-trials.

Before you join a study, learn about the possible risks and benefits and discuss all options with your health care professional.

*Investigational therapies have not been approved by the FDA or any other Regulatory Agency

2024-09-13T15:01:00

(BPT) – It might not feel like it now, but we know cooler temperatures are right around the corner which means now is the time to think about next season’s wardrobe. Luckily, Gerber Childrenswear’s biggest sale of the year is back — and bigger than ever. The fall Semi-Annual Sale has some of the year’s lowest prices on the things baby and toddlers need for a cozy and comfortable winter.

Whether you’re stocking up on favorites (hello footed pajamas!), bigger sizes for the entire crew or want to find a few new faves, there is a deal for every little one in your life. Get the most bang for your buck with these five picks:

The Original Onesies^® Brand Bodysuits

During Gerber’s Semi-Annual Sale, shoppers can score the original Onesies^® brand bodysuits for just $3 each — their lowest price of the year! Designed to make it easy for parents and super comfortable for babies, there’s a reason why Gerber Onesies have been the go-to outfit choice for more than four decades. With long-sleeve options available in solids and trendy prints, it’s the perfect time to stock up on bodysuits to take you through the seasons ahead.

Pajamas They’ll Want to Wear All Day

Ask any parent what their go-to outfit is for little ones and we’re willing to bet Sleep ‘N Plays top the list. They’re the ultimate leisure wear, specifically designed to keep babies comfy all day (and night) while they do the things they love. Scoop up multipacks in a variety of colors and prints during the sale as low as $5 each.

Personalized Towels and Blankets

Looking for a gift for a new baby in your life? Or getting a head start on holiday shopping? Whatever the reason, Gerber’s embroidered plush blankets and hooded towel sets are going for less than $25 — with personalization included! Grab both (and the matching security blanket!) and humbly accept your award as the family or friend group’s best gift giver.

Wearable Blankets for All Night Comfort

Launched earlier this year, wearable blankets from Gerber Childrenswear are the softest, coziest accessory to a baby’s bedtime routine. The ultra-plush microfleece options come in fun prints like florals and polar bears that will have your baby begging to go to bed (well, we can hope!). Most importantly, wearable blankets from the brand are the safest on the market, adhering to all industry safety standards so mom and dad can sleep well at night, too.

Daycare Basics Designed to Last

With the big kids back in school, now is the time to make sure your littlest learners’ closets are stocked with basics built for hands-on activities. From multi-packs of pants and dresses as low as $10, you won’t be able to go wrong when stocking up. Pro tip: grab a few multi-packs in a variety of sizes for easy transition between growth spurts.

Gerber Childrenswear is your one-stop-shop for baby and toddler essentials that won’t break the bank. Stock up on your favorite styles now through September 23.

2024-09-13T07:01:00

(BPT) – Learn more about one type of seizure children with epilepsy experience and find out about a clinical trial that may be available in your area. For more information, visit PGTCSeizureStudy.com.

2024-09-12T11:31:00

(BPT) – With a variety of powertrain options on the market, consumers who are shopping for a new vehicle have a lot to mull over these days. Buy another internal combustion engine (ICE) vehicle? Go fully electric? What about a hybrid? Regardless of vehicle type, it’s important for shoppers to understand the total cost of ownership before making a commitment, as this will help minimize unexpected expenses and headaches down the road.

“The ‘total cost of ownership’ equation includes factors like insurance premiums, fuel efficiency, repair expenses and home charging infrastructure if purchasing an electric vehicle (EV), among other aspects,” said Chong Gao, director of product management R&D at Mercury Insurance. “An EV, for example, might seem appealing for its expected fuel savings and lower maintenance costs, but insurance for them is on average 20% higher compared with an ICE vehicle, and they are typically more expensive to insure than hybrids as well. However, as more people adopt EVs and insurance companies gather more data in the future, their insurance costs will likely even out.”

When deciding between an ICE vehicle, hybrid or EV, here are some important distinctions to keep in mind:

Fueling/charging costs: Because hybrid vehicles have both a gas engine and electric motor, they are more fuel efficient than strictly ICE vehicles, as they can switch between the two motors while driving. Additionally, hybrids never need to be plugged in because the battery is recharged via the gas engine, eliminating the need to install home charging or navigate public chargers.

When it comes to charging EVs, the Department of Energy reports that about 80% of all charging is done at home, which J.D. Power notes is the ultimate convenience and most satisfying aspect of EV ownership. There are two types of EV charging solutions available for the home, both detailed at caranddriver.com. Consumers should be aware that they will need to consult an electrician to install a Level 2 charger, but some states and localities offer incentives to help cover the cost. Consumers should also be aware that satisfaction with public EV charging overall is still poor, according to many industry reports.

Maintenance: When it comes to maintenance for ICE and hybrid vehicles, there are several upkeep items that can add to the cost of ownership over time, such as air filters, oil changes and tire rotations. Both require similar maintenance schedules and incur comparable costs. One notable exception is that a hybrid’s battery will eventually need replacement, which can be costly, but U.S. law requires that all hybrids come with battery warranties of at least eight years or 100,000 miles, which should offer consumers peace of mind if they plan to keep the vehicle over the long term.

EVs, on the other hand, do not need many of these routine services as they lack an internal combustion engine, pistons, valves and moving parts. This can result in lower routine repair and maintenance costs compared with ICE and hybrid vehicles, but J.D. Power reports that EV owners replace tires more frequently than others. And like hybrids, the EV battery will also need to be replaced down the road, but all new EVs come with a generous battery warranty.

Insurance: While EVs may offer a number of advantages in terms of reduced maintenance and fueling costs, the cost of insurance might offset these potential savings. “EVs cost more to insure versus their ICE counterparts because they generally cost more to buy, and consequently more to repair or replace,” said Stephen Crewdson, senior director of insurance business intelligence at J.D. Power. “And while today’s EVs have fewer moving parts, it can be costly when they need replacement. If the battery pack is damaged, for example, the battery itself is a large expense and certain safety protocols are often necessary, which leads to a higher repair bill. Plus, there aren’t as many repair shops with technicians trained to work on EVs, which means these facilities can charge more for the specialized knowledge they provide.”

“The best vehicle type for a particular consumer will ultimately come down to budget, lifestyle factors and personal preference. Hybrids serve as a great bridge between ICE and EVs by offering fuel efficiency and a reduced carbon footprint for consumers who aren’t yet ready to make the leap to an EV,” said Gao.

2024-09-12T11:01:00

(BPT) – Are you ready for your next semester? There are plenty of school supplies you’ll need to get this summer, but there’s one that you shouldn’t overlook: Your laptop.

A laptop isn’t just another electronic device. It empowers you to complete your coursework and kick back with your own projects or downtime activities.

A new consideration to keep in mind since you bought a laptop is support for AI enhanced features. Laptops designed with AI in mind can help you take your school work (and other areas of your life) to the next level.

When looking for AI-powered laptops, choose those built with the Snapdragon X Elite Platform. Its powerful, intelligent and efficient processor offers cutting-edge responsiveness, so you can navigate demanding multi-tasking workloads across productivity, creativity, immersive entertainment and more.

Not sure where to start? Check out these five Snapdragon X Elite-powered laptops that cater to every type of student.

1. Lenovo Yoga Slim 7x

Artists of any media can unlock the freedom of creativity with the Lenovo Yoga Slim 7x. This powerhouse isn’t just smart. It’s your creative sidekick powered by AI that knows what you need before you do, streamlining creative tasks. This 14-inch laptop weighs just under 3 pounds, so you can create on the fly anywhere you go!

The Snapdragon X Elite processor allows the Yoga Slim to deliver top-tier performance while cutting power consumption by 68%. On one single charge, you can enjoy multi-day battery life allowing your creativity to flow for multiple days without a break.

2. HP OmniBook X

If you need help focusing on everyday tasks and want to increase your productivity, check out the HP OmniBook X. Utilize AI assistive technology to receive customized recommendations that adapt to your needs, habits and preferences. Enjoy multi-day battery life and HP Fast Charge, and stop worrying about interrupting your workflow. When you’re ready to relax with a movie or game, the Qualcomm Adreno GPU offers high-performance graphics and rich user experiences.

The OmniBook X is also perfect for distance learning and digital collaboration. Windows Studio Effects and Copilot+ collaboration tools (powered by Snapdragon X Elite Processor) facilitate crisp and clear conversations. Auto-adjust lighting, creative filters, eye contact enhancement, voice focus and a 5MP (16:10) camera ensure you can showcase your ideas to the classroom, collaborators and the world.

3. Samsung Galaxy Book4 Edge 16

If you’re constantly switching between phone and laptop at school and work, choose the Samsung Galaxy Book4 Edge 16. It offers users the ultimate connected experience, backed with Wi-Fi 72 readiness for quick and seamless cross-device connectivity. The hybrid approach allows you to control your Galaxy AI phone. Call, text, set reminders and more from the convenience of your PC.

Need to watch an international webinar or chat with others overseas? With Automatic Life Captions, you can get accurate subtitles in real time. With translations of 44 languages into English, you can leap over language barriers to learn and communicate worldwide.

4. Dell XPS 13

Do you need a computer for school, work, art and play? The Dell XPS 13 is the all-terrain vehicle of laptops that allows you to do it all. The Copilot+ on-device AI makes it easy to shop online, plan your next vacation and kick-start research for your class project in just a matter of minutes. Paired with 4K streaming and lossless audio, you can watch, share and create from anywhere with ease.

Thanks to the Snapdragon X Elite processor, you can enjoy cutting-edge responsiveness and unmatched speed for navigating demanding multitasking workloads with enhanced security and efficiency. It’s effortless to switch between multiple tasks, whether it’s productivity, browsers, video conferencing, collaboration or multimedia.

5. MSFT Surface Pro 11

If you want the best of both worlds, opt for the MSFT Surface Pro 11. What sets the Surface Pro apart from other 2-in-1 laptops/tablets is its flexibility.

The keyboard can be used when attached or detached, allowing you to position the device and keyboard to suit your needs. So, whether you’re taking notes in class, typing up a term paper or taking a break with a digital sketchbook, the Surface Pro adapts your life, however and wherever you use it.

This flexible and powerful 2-in-1 is built with Snapdragon X Elite. Like the other Snapdragon laptops, you can enjoy the AI-accelerated power and lightning-fast speed to keep up with you all day long.

Are you ready to buy your next laptop and level up your next semester? You can purchase any of these laptops direct from the manufacturer or online and in person at your local Best Buy.

Battery life varies significantly based on device, settings, usage, and other factors.

2024-09-12T07:15:00

(BPT) – This September is Better Breakfast Month, making it a perfect time to celebrate the meal that kicks off the day. The U.S. government encouraged citizens to eat better, well-balanced breakfasts during World War I. In 1951, the initiative gained momentum when the Cereal Institute boosted it in September as children returned to school and businesses ramped up following the slower summer months.

Research consistently shows that a healthy breakfast helps boost concentration, energy, and mood, setting a positive tone for the day. For many business and leisure travelers, breakfast may feel daunting due to the uncertainty of what their hotel offers — or doesn’t. Known for its signature made-to-order breakfast, Embassy Suites by Hilton is proving that hotel breakfast doesn’t have to be just a meal — it can be a launchpad for a day of success. Designed to energize your body, satisfy cravings, and accommodate varying dietary needs and preferences, Embassy Suites delivers a complimentary hot breakfast every morning to ensure you can start your day feeling ready to take on the world.

The brand’s signature made-to-order omelets, eggs the way you like them, and other breakfast favorites offer a deliciously personalized experience. Embassy Suites guests have enjoyed a whopping 2,431 miles of bacon in the past year, alongside more than 560,000 bagels and eight million sausages. And here’s a tasty tidbit: the chefs at each hotel crack an average of 116 eggs every single hour!

Here’s why Embassy Suites’ breakfast stands out from the rest and powers you for the day:

Be Welcomed by the Friendly Team: For many, breakfast may be the first interaction of the day. When staying at Embassy Suites, you are greeted by friendly, approachable team members, such as the chef and breakfast attendants. Embassy Suites team members aim to make a difference and build meaningful connections every day through their dedicated service — during breakfast and beyond.

Customize Your Made-To-Order Omelets: There’s nothing like made-to-order omelets or eggs the way you like them to kickstart your mornings on a flavorful and nutritious note. Perfect for those looking to add zest to their day, you can choose from a variety of fresh ingredients, including spinach, mushrooms, ham and cheese, for a personalized breakfast.

Choose from an Expansive Breakfast Selection: Travelers have various dietary needs, preferences and lifestyles, which may change day to day. Every morning, the robust breakfast spread offers something for everyone and you can choose delicious items to create a morning meal that suits your unique tastes.

Enjoy Hearty and Nourishing Options: Whether you’re looking for a well-balanced breakfast or have food allergies or dietary restrictions, you can maintain your wellness routine and dietary needs with nutritious items like fresh fruit, yogurt, oatmeal and more.

Relax and Eat in an Inviting Breakfast Area: Finding relaxing and inviting spaces to sit down, eat and prepare for the day ahead is important. With an upscale and contemporary atmosphere, you can enjoy your morning meal in comfort and ease at Embassy Suites.

Breakfast continues to be a beloved, signature part of the stay experience, which is why Embassy Suites is donating to World Central Kitchen during Better Breakfast Month to help support communities impacted by disasters worldwide.

Whether you’re traveling for leisure or business, Embassy Suites has perfected the art of breakfast by surpassing ordinary expectations.

2024-09-11T07:01:00

(BPT) – Fall is here and so is the back-to-school season. This is a busy time of year for families, and breakfast can often be forgotten in the hustle and bustle of weekday mornings.

To help you make your mornings brighter and your taste buds happier, KitchenAid, the #1 mixer brand in the world¹, offers five delightful recipes to keep your family fueled all morning long. These flavorful breakfast creations are perfect for busy mornings as well as cozy weekends.

1. 4-Ingredient Banana Pancakes

When you need a quick, no-fuss breakfast, try this four-ingredient banana pancake recipe. All you need is bananas, eggs, almond flour and sour cream.

Use the KitchenAid Go™ Cordless Hand Mixer to quickly combine the ingredients. With up to 60 minutes of continuous runtime² and no cord getting in the way, you can mix your ingredients at the counter, table or anywhere in the kitchen.

You can easily make this simple yet tasty breakfast recipe during a busy school and workweek in about 25 minutes!

Pro-tip: Use ripe bananas with lots of brown spots. They’re easier to mash and create much more flavorful pancakes.

2. Cherry Cream Cheese Breakfast Pastries

Cherry cream cheese breakfast pastries are a great breakfast item you can enjoy hot or cold. The pastries take about 40 minutes to make, so you can bake them in the morning or prep the night before and warm them in the oven before school and work.

Use the KitchenAid^® Stand Mixer, a must-have for cooking and baking, especially for busy families. This 5.5-quart bowl-lift stand mixer offers professional-style performance, 11 speeds (including 1/2 speed) and is compatible with over 10 attachments (sold separately), so you can fold, knead, mix, shred or beat whatever ingredients you need.

Serve the pastries for breakfast or Sunday brunch, or pack them for lunch as a sweet treat for your kids (or yourself!).

3. Banana Bread

Banana bread is a classic breakfast item that can be enjoyed as part of a complete breakfast, on its own or as an accompaniment to your coffee. Like banana pancakes, you’ll want to use ripe bananas for a more flavorful bread.

Combining the ingredients takes little time when using your Stand Mixer flat beater attachment. Because the banana bread takes over an hour to bake, it’s best to make them during the weekends. The recipe makes 24 servings, so you can easily make, bake and freeze the banana bread so your family can enjoy it all week long.

4. Waffles

Waffles are a timeless breakfast, and it’s easy to see why. They’re quick to make (about 20 minutes) and are infinitely customizable. Gather your family’s favorite toppings like chocolate syrup, maple syrup and whipped cream. Don’t forget to offer fresh fruit like blueberries, sliced strawberries or bananas!

Using your Stand Mixer or KitchenAid Go™ Cordless Hand Mixer, you can quickly and completely combine the ingredients before pouring the resulting batter into the waffle maker. You can save even more time by making the batter ahead of time and refrigerating it so all you have to do on a busy morning is to cook the batter in the waffle maker.

5. Pumpkin Muffins

Make the back-to-school season easier and celebrate the arrival of fall with pumpkin muffins! This is also a great recipe to try using your KitchenAid Go™ Cordless Hand Mixer and Stand Mixer to complete different tasks.

In your Stand Mixer, beat wet ingredients and sugar together. While the ingredients combine, use your KitchenAid Go™ Cordless Hand Mixer to combine dry ingredients in a separate bowl. After combining the wet and dry ingredients, toss in cranberries for a sweet and sour taste before pouring the batter into muffin tins lined with cups.

Once baked, you’ll have about 16 servings to enjoy right away or warm up the next morning.

Pro tip: Try adding cinnamon, cardamom or nutmeg to spice up muffins. Pumpkin has a sweet yet demure flavor that combines well with spices.

Let these five delicious breakfast recipes inspire you to add a creative and tasty twist to your morning routine this back-to-school season, throughout the fall and year-round. For more recipes, visit the KitchenAid page on Yummly.com.

Footnotes:

¹ Source Euromonitor International Limited; based on custom research conducted Oct. 2023 for value sales (in USD) in 2023 through all retail channels

² Maximum initial battery voltage (measured without a workload) is 12 volts. Nominal voltage is 10.8. Actual run time will vary based on recipe and/or attachments used. Battery life impacted by factors such as battery age and use.